Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Khadija Essafi-Benkhadir"'
Autor:
Marwa Kraiem, Sonia Ben Hamouda, Malek Eleroui, Marwa Ajala, Amal Feki, Amel Dghim, Zakaria Boujhoud, Marwa Bouhamed, Riadh Badraoui, Jean Marc Pujo, Khadija Essafi-Benkhadir, Hatem Kallel, Ibtissem Ben Amara
Publikováno v:
Marine Drugs, Vol 22, Iss 2, p 85 (2024)
In this study, we investigated for the first time the anti-inflammatory and immunomodulatory properties of crude polysaccharide (PSHT) extracted from green marine algae Halimeda tuna. PSHT exhibited anti-oxidant activity in vitro through scavenging 1
Externí odkaz:
https://doaj.org/article/bf56404534bc4758a056c96575f245c6
Autor:
Saoussen Mlayah-Bellalouna, Dorra Aissaoui-Zid, Aurelie Chantome, Jed Jebali, Soumaya Souid, Emna Ayedi, Hafedh Mejdoub, Maya Belghazi, Naziha Marrakchi, Khadija Essafi-Benkhadir, Christophe Vandier, Najet Srairi-Abid
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
The emerging concept of small conductance Ca2+-activated potassium channels (SKCa) as pharmacological target for cancer treatment has significantly increased in recent years. In this study, we isolated the P01 toxin from Androctonus australis (Aa) sc
Externí odkaz:
https://doaj.org/article/d4c991e53bfe45dea0b59b56dd54827c
Autor:
Maram Morjen, Ons Zakraoui, Zaineb Abdelkafi-Koubaa, Najet Srairi-Abid, Naziha Marrakchi, Khadija Essafi-Benkhadir, Jed Jebali
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12427 (2023)
Inflammation is associated with many pathology disorders and the malignant progression of most cancers. Therefore, targeting inflammatory pathways could provide a promising strategy for disease prevention and treatment. In this study, we experimental
Externí odkaz:
https://doaj.org/article/b55fb23ac74b44588be9035b22fc0826
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5600 (2023)
The study of the tumor microenvironment (TME) has become an important part of colorectal cancer (CRC) research. Indeed, it is now accepted that the invasive character of a primary CRC is determined not only by the genotype of the tumor cells, but als
Externí odkaz:
https://doaj.org/article/3bf44d6814924976a0afdbd8d7334d6d
Autor:
Amal Thebti, Ahmed Meddeb, Issam Ben Salem, Coulibaly Bakary, Sami Ayari, Farhat Rezgui, Khadija Essafi-Benkhadir, Abdellatif Boudabous, Hadda-Imene Ouzari
Publikováno v:
Antibiotics, Vol 12, Iss 2, p 225 (2023)
The emergence of antibiotics-resistant bacteria has been a serious concern for medical professionals over the last decade. Therefore, developing new and effective antimicrobials with modified or different modes of action is a continuing imperative. I
Externí odkaz:
https://doaj.org/article/b3c16d3e99f84b7693bb08868ab31b9b
Autor:
Yosser Zina Abdelkrim, Emna Harigua-Souiai, Imen Bassoumi-Jamoussi, Mourad Barhoumi, Josette Banroques, Khadija Essafi-Benkhadir, Michael Nilges, Arnaud Blondel, N. Kyle Tanner, Ikram Guizani
Publikováno v:
Molecules, Vol 27, Iss 18, p 5890 (2022)
Previous investigations of the Leishmania infantum eIF4A-like protein (LieIF4A) as a potential drug target delivered cholestanol derivatives inhibitors. Here, we investigated the mode of action of cholesterol derivatives as a novel scaffold structure
Externí odkaz:
https://doaj.org/article/dd3b2dc394d34a8a8f9fc27de5aab333
Autor:
Dorra Aissaoui-Zid, Mohamed-Chiheb Saada, Wassim Moslah, Marie Potier-Cartereau, Aude Lemettre, Houcemeddine Othman, Marc Gaysinski, Zaineb Abdelkafi-Koubaa, Soumaya Souid, Naziha Marrakchi, Christophe Vandier, Khadija Essafi-Benkhadir, Najet Srairi-Abid
Publikováno v:
Molecules, Vol 26, Iss 24, p 7610 (2021)
Glioblastoma is an aggressive cancer, against which medical professionals are still quite helpless, due to its resistance to current treatments. Scorpion toxins have been proposed as a promising alternative for the development of effective targeted g
Externí odkaz:
https://doaj.org/article/317e861db8ee4ed1b26e26030a3f934e
Pharmacological Investigation of CC-LAAO, an L-Amino Acid Oxidase from Cerastes cerastes Snake Venom
Autor:
Zaineb Abdelkafi-Koubaa, Ines ELBini-Dhouib, Soumaya Souid, Jed Jebali, Raoudha Doghri, Najet Srairi-Abid, Khadija Essafi-Benkhadir, Olivier Micheau, Naziha Marrakchi
Publikováno v:
Toxins, Vol 13, Iss 12, p 904 (2021)
Snake venom proteins, which are responsible for deadly snakebite envenomation, induce severe injuries including neurotoxicity, myotoxicity, cardiotoxicity, hemorrhage, and the disruption of blood homeostasis. Yet, many snake-venom proteins have been
Externí odkaz:
https://doaj.org/article/ebd0cac0864e4df6aabeae052fe72719
Autor:
Emna Harigua-Souiai, Yosser Zina Abdelkrim, Imen Bassoumi-Jamoussi, Ons Zakraoui, Guillaume Bouvier, Khadija Essafi-Benkhadir, Josette Banroques, Nathan Desdouits, Hélène Munier-Lehmann, Mourad Barhoumi, N Kyle Tanner, Michael Nilges, Arnaud Blondel, Ikram Guizani
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 1, p e0006160 (2018)
Leishmaniases are neglected parasitic diseases in spite of the major burden they inflict on public health. The identification of novel drugs and targets constitutes a research priority. For that purpose we used Leishmania infantum initiation factor 4
Externí odkaz:
https://doaj.org/article/ebb7e2223ed14d3b805b46d2c9ede416
Autor:
Safa Tarhouni-Jabberi, Ons Zakraoui, Efstathia Ioannou, Ichrak Riahi-Chebbi, Meriam Haoues, Vassilios Roussis, Riadh Kharrat, Khadija Essafi-Benkhadir
Publikováno v:
Marine Drugs, Vol 15, Iss 7, p 221 (2017)
Conventional treatment of advanced colorectal cancer is associated with tumor resistance and toxicity towards normal tissues. Therefore, development of effective anticancer therapeutic alternatives is still urgently required. Nowadays, marine seconda
Externí odkaz:
https://doaj.org/article/be737c4a0df84520841f15d93398fa12