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pro vyhledávání: '"Khadija Debri"'
Autor:
Shinichi Kobayashi, Donald S. Davies, Khadija Debri, Hironori Nakura, Patrick J Brassil, Robert Edwards
Publikováno v:
Biochemical Pharmacology. 56:253-257
A strain of hyperlipidaemic Sprague-Dawley (HSD) rat was compared with normal Sprague-Dawley (SD) rats for expression of cholesterol 7alpha-hydroxylase activity (CYP7A1) and other cytochrome P450 (P450) enzymes in liver. Hepatic microsomal CYP7A1 act
Publikováno v:
Biochemical Pharmacology. 50:2047-2056
Previously, we have shown that highly specific antibodies against cytochrome P450 enzymes can be produced by targeting a 5-amino acid sequence at the C-terminus. Although rat CYP3A1 and CYP3A2 share 89% amino acid sequence similarity, they differ by