Novel GSK-3β Inhibitor Neopetroside A Protects Against Murine Myocardial Ischemia/Reperfusion Injury

Autor: Kim, Hyoung Kyu, Kim, Min, Marquez, Jubert C., Jeong, Seung Hun, Ko, Tae Hee, Noh, Yeon Hee, Kha, Pham Trong, Choi, Ha Min, Kim, Dong Hyun, Kim, Jong Tae, Yang, Young Il, Ko, Kyung Soo, Rhee, Byoung Doo, Shubina, Larisa K., Makarieva, Tatyana N., Yashunsky, Dmitry Y., Gerbst, Alexey G., Nifantiev, Nikolay E., Stonik, Valentin A., Han, Jin

Publikováno v: In JACC: Basic to Translational Science November 2022 7(11):1102-1116

BH4 activates CaMKK2 and rescues the cardiomyopathic phenotype in rodent models of diabetes.

Autor: Kim HK; Department of Physiology, BK21 Plus Project Team, College of Medicine, Smart Marine Therapeutics Center, Cardiovascular and Metabolic Disease Center, Inje University, Busan, Republic of Korea., Ko TH; Department of Physiology, BK21 Plus Project Team, College of Medicine, Smart Marine Therapeutics Center, Cardiovascular and Metabolic Disease Center, Inje University, Busan, Republic of Korea., Song IS; Department of Physiology, BK21 Plus Project Team, College of Medicine, Smart Marine Therapeutics Center, Cardiovascular and Metabolic Disease Center, Inje University, Busan, Republic of Korea., Jeong YJ; Department of Physiology, BK21 Plus Project Team, College of Medicine, Smart Marine Therapeutics Center, Cardiovascular and Metabolic Disease Center, Inje University, Busan, Republic of Korea., Heo HJ; Department of Physiology, BK21 Plus Project Team, College of Medicine, Smart Marine Therapeutics Center, Cardiovascular and Metabolic Disease Center, Inje University, Busan, Republic of Korea., Jeong SH; Department of Physiology, BK21 Plus Project Team, College of Medicine, Smart Marine Therapeutics Center, Cardiovascular and Metabolic Disease Center, Inje University, Busan, Republic of Korea., Kim M; Department of Physiology, BK21 Plus Project Team, College of Medicine, Smart Marine Therapeutics Center, Cardiovascular and Metabolic Disease Center, Inje University, Busan, Republic of Korea., Park NM; Department of Physiology, BK21 Plus Project Team, College of Medicine, Smart Marine Therapeutics Center, Cardiovascular and Metabolic Disease Center, Inje University, Busan, Republic of Korea., Seo DY; Department of Physiology, BK21 Plus Project Team, College of Medicine, Smart Marine Therapeutics Center, Cardiovascular and Metabolic Disease Center, Inje University, Busan, Republic of Korea., Kha PT; Department of Physiology, BK21 Plus Project Team, College of Medicine, Smart Marine Therapeutics Center, Cardiovascular and Metabolic Disease Center, Inje University, Busan, Republic of Korea., Kim SW; Department of Physiology, BK21 Plus Project Team, College of Medicine, Smart Marine Therapeutics Center, Cardiovascular and Metabolic Disease Center, Inje University, Busan, Republic of Korea., Lee SR; Department of Physiology, BK21 Plus Project Team, College of Medicine, Smart Marine Therapeutics Center, Cardiovascular and Metabolic Disease Center, Inje University, Busan, Republic of Korea., Cho SW; Department of Physiology, BK21 Plus Project Team, College of Medicine, Smart Marine Therapeutics Center, Cardiovascular and Metabolic Disease Center, Inje University, Busan, Republic of Korea.; Division of Cardiology, Department of Internal Medicine, Inje University College of Medicine, Ilsan Paik Hospital, Goyang, Korea., Won JC; Department of Physiology, BK21 Plus Project Team, College of Medicine, Smart Marine Therapeutics Center, Cardiovascular and Metabolic Disease Center, Inje University, Busan, Republic of Korea., Youm JB; Department of Physiology, BK21 Plus Project Team, College of Medicine, Smart Marine Therapeutics Center, Cardiovascular and Metabolic Disease Center, Inje University, Busan, Republic of Korea., Ko KS; Department of Physiology, BK21 Plus Project Team, College of Medicine, Smart Marine Therapeutics Center, Cardiovascular and Metabolic Disease Center, Inje University, Busan, Republic of Korea., Rhee BD; Department of Physiology, BK21 Plus Project Team, College of Medicine, Smart Marine Therapeutics Center, Cardiovascular and Metabolic Disease Center, Inje University, Busan, Republic of Korea., Kim N; Department of Physiology, BK21 Plus Project Team, College of Medicine, Smart Marine Therapeutics Center, Cardiovascular and Metabolic Disease Center, Inje University, Busan, Republic of Korea., Cho KI; Division of Cardiology, Department of Internal Medicine, College of Medicine, Kosin University, Busan, Republic of Korea., Shimizu I; Department of Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan., Minamino T; Department of Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan., Ha NC; Department of Agricultural Biotechnology, Seoul National University, Seoul, Republic of Korea., Park YS; School of Biotechnology and Biomedical Science, Inje University, Kimhae, Republic of Korea., Nilius B; Katholieke Universiteit Leuven, Department of Cellular and Molecular Medicine, Leuven, Belgium., Han J; Department of Physiology, BK21 Plus Project Team, College of Medicine, Smart Marine Therapeutics Center, Cardiovascular and Metabolic Disease Center, Inje University, Busan, Republic of Korea phyhanj@inje.ac.kr.

Publikováno v: Life science alliance [Life Sci Alliance] 2020 Jul 22; Vol. 3 (9). Date of Electronic Publication: 2020 Jul 22 (Print Publication: 2020).