Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Kh. Reeta"'
Publikováno v:
Biomarkers in Medicine. 16:821-832
Lp-PLA2 is an enzyme encoded by the PLA2G7 gene located at chromosome 6p12-21, which is included in different signal transduction pathways. The potential of serum levels of Lp-PLA2 as a marker of inflammation quantifying cardio-metabolic risk, renal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ab7741270f3ec9193adb2f41ba5d000
https://doi.org/10.2217/bmm-2021-1129
https://doi.org/10.2217/bmm-2021-1129
Publikováno v:
Cellular and Molecular Neurobiology. 42:2003-2017
Despite achieving remarkable success in understanding the cellular, molecular and pathophysiological aspects of stroke, translation from preclinical research has always remained an area of debate. Although thousands of experimental compounds have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f607173fb35d47b3ec0d342acdb0c050
https://doi.org/10.1007/s10571-021-01083-6
https://doi.org/10.1007/s10571-021-01083-6
Publikováno v:
Brain Research Bulletin. 168:165-177
The discovery and development of safinamide, an alpha-aminoamide, has been a valuable addition to the existing clinical management of Parkinson’s disease (PD). The journey of safinamide dates back to the year 1983, when an alpha-aminoamide called m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d83d8143ab139d06a793245cb4869509
https://doi.org/10.1016/j.brainresbull.2020.12.018
https://doi.org/10.1016/j.brainresbull.2020.12.018
Publikováno v:
Journal of clinical pharmacologyReferences. 62(6)
Serotonin-dopamine activity modulators (SDAMs) have been approved as an adjunctive treatment to antidepressants in patients with inadequate response. These drugs have been proposed to have a beneficial effect on cognition, sleep-related problems, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96feff0be04a0dcb45474237a316bd0d
https://pubmed.ncbi.nlm.nih.gov/34967946
https://pubmed.ncbi.nlm.nih.gov/34967946
Publikováno v:
Indian Journal of Pharmacology
Treatment of cancer is a major challenge even though the pathophysiology is becoming clearer with time. A number of new chemical entities are developed to target cancer growth inhibition, but the targeted delivery of these products still needs novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b08dc55d5e523afa813e634e3d47560
https://pubmed.ncbi.nlm.nih.gov/33283772
https://pubmed.ncbi.nlm.nih.gov/33283772
Publikováno v:
Free Radical Biology and Medicine
Free Radical Biology & Medicine
Free Radical Biology & Medicine
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to infect hundred thousands of people every day worldwide. Since it is a novel virus, research continues to update the possible thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::776c609bf4f2dc839c9ab2638e0ae460
Publikováno v:
European journal of clinical pharmacology. 76(9)
The aim of this article is to understand the pros and cons of various methods involved in first-in-human (FIH) dose calculation and act decisively in dose escalations when calculating the maximum tolerated dose. We reviewed early phase clinical trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55fd221933f3fe3ec8fa402ecec33a03
https://pubmed.ncbi.nlm.nih.gov/32488334
https://pubmed.ncbi.nlm.nih.gov/32488334
Publikováno v:
Journal of Stroke and Cerebrovascular Diseases. 31:106349
Glycogen synthase kinase-3β (GSK-3β), a serine/threonine protein kinase, gets activated and worsen stroke outcome after ischemia/reperfusion (I/R) injury by inducing inflammation and apoptosis. In this study, tideglusib, a selective irreversible an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::630074f79ac7a1fb9bcb9c695804452c
https://doi.org/10.1016/j.jstrokecerebrovasdis.2022.106349
https://doi.org/10.1016/j.jstrokecerebrovasdis.2022.106349
Autor:
Soheb Anwar Mohammed, Sandeep Seth, Himanshu Meghwani, Pankaj Prabhakar, Palak Galhotra, Subir Kumar Maulik, Kh. Reeta, Ruma Ray, Milind Padmakar Hote, Sanjay K. Banerjee
Publikováno v:
Molecular and Cellular Biochemistry. 449:185-194
Pulmonary hypertension (PH) is a morbid complication of cardiopulmonary as well as several systemic diseases in humans. It is rapidly progressive and fatal if left untreated. In the present study, we investigated the effect of PPARα agonist fenofibr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71af0a87598266eb491b15adae447c7
https://doi.org/10.1007/s11010-018-3355-3
https://doi.org/10.1007/s11010-018-3355-3
Publikováno v:
Neurochemistry International. 108:146-156
The present study investigated the neuroprotective effects of taurine, an essential amino acid for growth and development of central nervous system. Intracerebroventricular streptozotocin (ICV-STZ) model of cognitive impairment was used in male Wista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f96cac9221f8d83f90b2d9f04d57ad
https://doi.org/10.1016/j.neuint.2017.03.006
https://doi.org/10.1016/j.neuint.2017.03.006