Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Kh. Kh. Semenov"'
1
A New Diagnostic Approach to Assessing Tissue Changes in Type 2 Diabetes Mellitus in Mice Using 'LASMA ST' Device
Autor: O. I. Stepanova, R. A. Klesov, Kh. Kh. Semenov, I. A. Pomytkin, V. N. Karkischenko
Publikováno v: Journal Biomed. 18:37-44
For the first time, LASMA ST, a device for laser diagnostic, was adapted for preclinical studies on laboratory db/db mouse genetic models of type 2 diabetes. The proposed method for studying of tissue changes during diabetes mellitus consists in a si
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dcb12e92e839d729fabf08a3baa10d07
https://doi.org/10.33647/2074-5982-18-3-37-44
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2
[An electron microscopic study of retinal development and pathogenesis in mutant CBA/J mice with hereditary retinal degeneration]
Autor: V A, Poplinskaia, O G, Stroeva, Kh Kh, Semenov
Publikováno v: Izvestiia Akademii nauk. Seriia biologicheskaia. (6)
Electron microscopic study of the neural retina pathogenesis was carried out on mice CBA/J in comparison with corresponding process in substrain CBA/Ki (Caley et al., 1972). A difference in terms of the pathology development was found between substra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::408f4561d55c7ede5252e6eb451bf673
https://pubmed.ncbi.nlm.nih.gov/1292809
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4
Assessment of the contribution of thiophosphamide-induced chromosomal aberrations to preimplantation embryonic mortality in mice
Autor: Kh. Kh. Semenov, A. M. Malashenko
Publikováno v: Bulletin of Experimental Biology and Medicine. 88:1074-1076
Thiotepa-induced perimplantation mortality in mice was analysed cytologically. The contribution of induced chromosomal aberrations to preimplantation embryonic death was studied. Under the influence of 1.25 mg/kg of thiotepa on late spermatids the st
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e583b9ab9a6bfb0af9631b225b4d39c8
https://doi.org/10.1007/bf00799287
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5
Cytological study of early embryonic mortality in laboratory mice
Autor: Kh. Kh. Semenov, A. M. Malashenko
Publikováno v: Bulletin of Experimental Biology and Medicine. 80:1249-1251
Early embryogenesis was studied cytologicaly in laboratory mice. Preimplantation embryonic mortality among DBA/2JY, C57BL/6JY, and 101/HY mice and among CBWA females crossed with B6 males did not exceed 4–6%. An exception was the AKR/JY mice, with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e71025d734c5539cd4d3b1f10cc805a
https://doi.org/10.1007/bf00833176
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6
[Demonstration of dominant lethal mutations in early mouse embryogenesis]
Autor: Kh Kh, Semenov, A M, Malashenko
Publikováno v: Genetika. 17(3)
Male mice of C57Bl/6Y strain were injected intraperitoneally with 2.5 and 5 mg/kg doses of thioTEPA. Males were mated to tetrahybrid CBWA females during the second week after the treatment. Embryonic mortality was studied by two methods: by standard
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9596e5f7f66f607380665f4f267b1f64
https://pubmed.ncbi.nlm.nih.gov/6788647
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7
[Cytological study of early embryonic mortality in laboratory mice]
Autor: Kh Kh, Semenov, A M, Malashenko
Publikováno v: Biulleten' eksperimental'noi biologii i meditsiny. 80(10)
Early embryogenesis of laboratory mice was studied cytologically. Preimplantation embryonic mortality in mice of the strains DBA/21Y, C57BL/61Y, 101/HY and in the CBWA females crossed with the B6 males did not exceed 4--6%. Mice of the strain AKRIY s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::763463a236097bb454089c773949e2ca
https://pubmed.ncbi.nlm.nih.gov/819058
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8
[Mutagenic effect of chemical compounds on laboratory mice]
Autor: A M, Malashenko, Kh Kh, Semenov, G P, Selezneva, N I, Surkova
Publikováno v: Genetika. 14(1)
Mutagenic effect of thioTEPA applied at a dose of 1.25 mg/kg was studied in late spermatids of C57BL/L male mice. The mutagen induced dominant lethal mutations in germ cells (39%) and symmetric translocations in 33.5% of F1 male offspring. The common
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::de2c6623cf8cdfd032dc2963f59047a7
https://pubmed.ncbi.nlm.nih.gov/414963
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9
[Estimation of the contribution of thiophosphamide-induced chromosomal aberrations to perimplantation embryonic mortality in mice]
Autor: Kh Kh, Semenov, A M, Malashenko
Publikováno v: Biulleten' eksperimental'noi biologii i meditsiny. 88(9)
Thiotepa-induced perimplantation mortality in mice was analysed cytologically. The contribution of induced chromosomal aberrations to preimplantation embryonic death was studied. Under the influence of 1.25 mg/kg of thiotepa on late spermatids the st
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::78c098e284dee4ae95afddad9ababaa4
https://pubmed.ncbi.nlm.nih.gov/117855
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10
[Role of female genotype in manifestation of dominant lethal mutations induced by thiophosphamide in the spermatids of male rats]
Autor: A M, Malashenko, Kh Kh, Semenov
Publikováno v: Genetika. 16(11)
Hybrid male mice FICD2 were injected intraperitoneally with thioTEPA at a dose of 1.5 mg/kg or 2.0 mg/kg. During the second week after the treatment males were mated with females of 101/HY, C57BL/6JY and CBA/LacY strains, and embryoic mortality was s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1d6d473d6bf2c9f7f2821978acb5b35a
https://pubmed.ncbi.nlm.nih.gov/6780410
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