Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Kgagudi P"'
Publikováno v:
Journal of Medical Case Reports, Vol 18, Iss 1, Pp 1-3 (2024)
Abstract Background Telangiectatic osteosarcoma is rare and it rarely affects flat bones, especially the bones of the pelvis. It is uncommon for telangiectatic osteosarcoma to be considered as a differential diagnosis when assessing a large intrabdom
Externí odkaz:
https://doaj.org/article/f5b2c3b6f18e408b8fa47095a6feb716
Publikováno v:
Journal of Medical Case Reports, Vol 17, Iss 1, Pp 1-4 (2023)
Abstract Background Infective arthritis is an orthopaedic surgical emergency. Staphylococcus aureus remains the commonest causative bacteria across all age groups. Prevotella spp. as a cause of infective arthritis is extremely rare. Case report We pr
Externí odkaz:
https://doaj.org/article/402ba041158f4f39865bcbe03cbd331f
Autor:
Catherine Riou, Jinal N Bhiman, Yashica Ganga, Shobna Sawry, Frances Ayres, Richard Baguma, Sashkia R Balla, Ntombi Benede, Mallory Bernstein, Asiphe S Besethi, Sandile Cele, Carol Crowther, Mrinmayee Dhar, Sohair Geyer, Katherine Gill, Alba Grifoni, Tandile Hermanus, Haajira Kaldine, Roanne S Keeton, Prudence Kgagudi, Khadija Khan, Erica Lazarus, Jean Le Roux, Gila Lustig, Mashudu Madzivhandila, Siyabulela F J Magugu, Zanele Makhado, Nelia P Manamela, Qiniso Mkhize, Paballo Mosala, Thopisang P Motlou, Hygon Mutavhatsindi, Nonkululeko B Mzindle, Anusha Nana, Rofhiwa Nesamari, Amkele Ngomti, Anathi A Nkayi, Thandeka P Nkosi, Millicent A Omondi, Ravindre Panchia, Faeezah Patel, Alessandro Sette, Upasna Singh, Strauss van Graan, Elizabeth M Venter, Avril Walters, Thandeka Moyo-Gwete, Simone I Richardson, Nigel Garrett, Helen Rees, Linda-Gail Bekker, Glenda Gray, Wendy A Burgers, Alex Sigal, Penny L Moore, Lee Fairlie
Publikováno v:
PLOS Global Public Health, Vol 4, Iss 4, p e0002703 (2024)
We report the safety and immunogenicity of fractional and full dose Ad26.COV2.S and BNT162b2 in an open label phase 2 trial of participants previously vaccinated with a single dose of Ad26.COV2.S, with 91.4% showing evidence of previous SARS-CoV-2 in
Externí odkaz:
https://doaj.org/article/ffaf584224f64bc08915eb129bbe87ff
Autor:
Jinal N. Bhiman, Simone I. Richardson, Bronwen E. Lambson, Prudence Kgagudi, Nonkululeko Mzindle, Haajira Kaldine, Carol Crowther, Glenda Gray, Linda-Gail Bekker, Novavax trial clinical lead author group, Vivek Shinde, Chijioke Bennett, Gregory M. Glenn, Shabir A. Madhi, Penny L. Moore
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-5 (2023)
Abstract The SARS-CoV-2 Omicron (B.1.1.529) Variant of Concern (VOC) and its sub-lineages (including BA.2, BA.4, BA.5, BA.2.12.1) contain spike mutations that confer high level resistance to neutralizing antibodies induced by vaccination with ancestr
Externí odkaz:
https://doaj.org/article/6e50f56803a24a00a13ebf541e441d6d
Autor:
Thandeka Moyo-Gwete, Cathrine Scheepers, Zanele Makhado, Prudence Kgagudi, Nonkululeko B. Mzindle, Rutendo Ziki, Sharon Madzorera, Nelia P. Manamela, Frances Ayres, Bronwen E. Lambson, Simone I. Richardson, Lynn Morris, Penny L. Moore
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Antibodies with the same variable region can exist as multiple isotypes with varying neutralization potencies, though the mechanism for this is not fully defined. We previously isolated an HIV-directed IgA1 monoclonal antibody (mAb), CAP88-C
Externí odkaz:
https://doaj.org/article/c2c5fc6c15e34f56b2798fa353ccefee
Autor:
Boitumelo M. Motsoeneng, Nelia P. Manamela, Haajira Kaldine, Prudence Kgagudi, Tandile Hermanus, Frances Ayres, Zanele Makhado, Thandeka Moyo-Gwete, Mieke A. van der Mescht, Fareed Abdullah, Michael T. Boswell, Veronica Ueckermann, Theresa M. Rossouw, Shabir A. Madhi, Penny L. Moore, Simone I. Richardson
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
The kinetics of Fc-mediated functions following SARS-CoV-2 infection or vaccination in people living with HIV (PLWH) are not known. We compared SARS-CoV-2 spike-specific Fc functions, binding, and neutralization in PLWH and people without HIV (PWOH)
Externí odkaz:
https://doaj.org/article/c33845a85ecd48a4a196b848e6494360
Autor:
Nonhlanhla N Mkhize, Anna E J Yssel, Haajira Kaldine, Rebecca T van Dorsten, Amanda S Woodward Davis, Nicolas Beaume, David Matten, Bronwen Lambson, Tandile Modise, Prudence Kgagudi, Talita York, Dylan H Westfall, Elena E Giorgi, Bette Korber, Colin Anthony, Rutendo E Mapengo, Valerie Bekker, Elizabeth Domin, Amanda Eaton, Wenjie Deng, Allan DeCamp, Yunda Huang, Peter B Gilbert, Asanda Gwashu-Nyangiwe, Ruwayhida Thebus, Nonkululeko Ndabambi, Dieter Mielke, Nyaradzo Mgodi, Shelly Karuna, Srilatha Edupuganti, Michael S Seaman, Lawrence Corey, Myron S Cohen, John Hural, M Juliana McElrath, James I Mullins, David Montefiori, Penny L Moore, Carolyn Williamson, Lynn Morris
Publikováno v:
PLoS Pathogens, Vol 19, Iss 6, p e1011469 (2023)
The VRC01 Antibody Mediated Prevention (AMP) efficacy trials conducted between 2016 and 2020 showed for the first time that passively administered broadly neutralizing antibodies (bnAbs) could prevent HIV-1 acquisition against bnAb-sensitive viruses.
Externí odkaz:
https://doaj.org/article/1a870a5047ec41f0af5508300c65082a
Autor:
Cathrine Scheepers, Josie Everatt, Daniel G. Amoako, Houriiyah Tegally, Constantinos Kurt Wibmer, Anele Mnguni, Arshad Ismail, Boitshoko Mahlangu, Bronwen E. Lambson, Darren P. Martin, Eduan Wilkinson, James Emmanuel San, Jennifer Giandhari, Nelia Manamela, Noxolo Ntuli, Prudence Kgagudi, Sandile Cele, Simone I. Richardson, Sureshnee Pillay, Thabo Mohale, Upasana Ramphal, Yeshnee Naidoo, Zamantungwa T. Khumalo, Gaurav Kwatra, Glenda Gray, Linda-Gail Bekker, Shabir A. Madhi, Vicky Baillie, Wesley C. Van Voorhis, Florette K. Treurnicht, Marietjie Venter, Koleka Mlisana, Nicole Wolter, Alex Sigal, Carolyn Williamson, Nei-yuan Hsiao, Nokukhanya Msomi, Tongai Maponga, Wolfgang Preiser, Zinhle Makatini, Richard Lessells, Penny L. Moore, Tulio de Oliveira, Anne von Gottberg, Jinal N. Bhiman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
The SARS-CoV-2 PANGO lineage C.1.2 has been under monitoring by global health authorities as it has spread worldwide. Here, Bhiman and colleagues characterise the emergence of the lineage, and its neutralisation sensitivity using data from vaccinees
Externí odkaz:
https://doaj.org/article/e365317a28774fd29c4b6a0f6a77a17a
Autor:
Cathrine Scheepers, Prudence Kgagudi, Nonkululeko Mzindle, Elin S Gray, Thandeka Moyo-Gwete, Bronwen E Lambson, Brent Oosthuysen, Batsirai Mabvakure, Nigel J Garrett, Salim S Abdool Karim, Lynn Morris, Penny L Moore
Publikováno v:
PLoS Pathogens, Vol 18, Iss 9, p e1010450 (2022)
Broadly neutralizing antibodies (bNAbs) that target the membrane-proximal external region (MPER) of HIV gp41 envelope, such as 4E10, VRC42.01 and PGZL1, can neutralize >80% of viruses. These three MPER-directed monoclonal antibodies share germline an
Externí odkaz:
https://doaj.org/article/fbf5268d0dd44dbbb5f2f8afb6a19d60
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