Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kfir Molakandov"'
Autor:
Marc Gotkine, Yoseph Caraco, Yossef Lerner, Simcha Blotnick, Maor Wanounou, Shalom Guy Slutsky, Judith Chebath, Graciela Kuperstein, Elena Estrin, Tamir Ben-Hur, Arik Hasson, Kfir Molakandov, Tehila Sonnenfeld, Yafit Stark, Ariel Revel, Michel Revel, Michal Izrael
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background Malfunction of astrocytes is implicated as one of the pathological factors of ALS. Thus, intrathecal injection of healthy astrocytes in ALS can potentially compensate for the diseased astrocytes. AstroRx® is an allogeneic cell-ba
Externí odkaz:
https://doaj.org/article/3ddbc58896384d3a9d1071138a07d1a3
Autor:
Michal Izrael, Kfir Molakandov, Ariel Revel, Shalom Guy Slutsky, Tehila Sonnenfeld, Julia Miriam Weiss, Michel Revel
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Background: An acute respiratory distress syndrome (ARDS) is caused by the increased amounts of pro-inflammatory cytokines and neutrophil-mediated tissue injury. To date, there is no effective treatment for the ARDS available, while the need for one
Externí odkaz:
https://doaj.org/article/4e669f64b52142248ccc4e18b56f57ea
Autor:
Dana Berneman-Zeitouni, Kfir Molakandov, Marina Elgart, Eytan Mor, Alessia Fornoni, Miriam Ramírez Domínguez, Julie Kerr-Conte, Michael Ott, Irit Meivar-Levy, Sarah Ferber
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87812 (2014)
Lineage-specific transcription factors (TFs) display instructive roles in directly reprogramming adult cells into alternate developmental fates, in a process known as transdifferentiation. The present study analyses the hypothesis that despite being
Externí odkaz:
https://doaj.org/article/9d50661e749b45b18a35516f9a7ce121
Autor:
Marc Gotkine, Yoseph Caraco, Yossef Lerner, Simcha Blotnick, Maor Wanounou, Shalom Guy Guy Slutsky, Judith Chebath, Graciela Kuperstein, elena estrin, Tamir Ben-Hur, Arik Hasson, Kfir Molakandov, Tehila Sonnenfeld, Yafit Stark, Ariel Revel, Michel Revel, Michal Izrael
Background: AstroRx is an allogeneic cell-based product, composed of healthy and functional human astrocytes derived from embryonic stem cells. We previously showed that AstroRx protects neurons in ALS animal models by multiple mechanisms, including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c367fbb256e70677d5f503149589df3f
https://doi.org/10.21203/rs.3.rs-2275247/v1
https://doi.org/10.21203/rs.3.rs-2275247/v1
Autor:
Kfir Molakandov, Denise A. Berti, Avital Beck, Ofer Elhanani, Michael D. Walker, Yoav Soen, Karina Yavriyants, Michal Zimerman, Ella Volman, Itzik Toledo, Anna Erukhimovich, Alon M. Levy, Arik Hasson, Joseph Itskovitz-Eldor, Judith Chebath, Michel Revel
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Frontiers in Endocrinology
Frontiers in Endocrinology
BackgroundCell therapy of diabetes aims at restoring the physiological control of blood glucose by transplantation of functional pancreatic islet cells. A potentially unlimited source of cells for such transplantations would be islet cells derived fr
Autor:
Kfir Molakandov, Ella Volman, Michael D. Walker, Yoav Soen, Anna Eruhimovich, Alon Levy, Arik Hasson, Karina Yavriyants, Yitzhak Toledo, Avital Beck, Michal Zimerman, Judith Chebath, Joseph Itskovitz-Eldor, Denise Aparecida Berti, Michel Revel, Ofer Elhanani
BackgroundCell therapy of diabetes aims at restoring the physiological control of blood glucose by transplantation of functional pancreatic islet cells. Human islets from post-mortem donations have shown efficiency but the demand for islets vastly ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16e48f84b218c9e14b65872e37d4fe84
https://doi.org/10.21203/rs.3.rs-23915/v1
https://doi.org/10.21203/rs.3.rs-23915/v1
Autor:
Irit Meivar-Levy, Marina Ben-Shimon, Sarah Ferber, Hila Barash, Kfir Molakandov, Rolf Gebhardt, Fatima Zoabi, Michael Gurevich, Shoshana Greenberger, Adi Har-Zahav, Frank Gaunitz, Eytan Mor, Helit Cohen, Philippe Ravassard
Publikováno v:
Hepatology
Hepatology, Wiley-Blackwell, 2018, 68 (4), pp.1589-1603. ⟨10.1002/hep.29827⟩
Hepatology, Wiley-Blackwell, 2018, 68 (4), pp.1589-1603. ⟨10.1002/hep.29827⟩
Transdifferentiation (TD) is the direct reprogramming of adult cells into cells of alternate fate and function. We have previously shown that liver cells can be transdifferentiated into beta-like, insulin-producing cells through ectopic expression of
Autor:
Eytan Mor, Sarah Ferber, Dana Berneman, Shiraz Gefen-Halevi, Irit Meivar-Levy, Itzhak H. Rachmut, Kfir Molakandov
Publikováno v:
Cellular Reprogramming. 12:655-664
Reprogramming adult mammalian cells is an attractive approach for generating cell-based therapies for degenerative diseases, such as diabetes. Adult human liver cells exhibit a high level of developmental plasticity and have been suggested as a poten
Autor:
Kfir Molakandov, Alessia Fornoni, Dana Berneman-Zeitouni, Irit Meivar-Levy, Eytan Mor, Michael Ott, Miriam Ramírez Domínguez, Julie Kerr-Conte, Sarah Ferber, Marina Elgart
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87812 (2014)
PLoS ONE
PLoS ONE
Lineage-specific transcription factors (TFs) display instructive roles in directly reprogramming adult cells into alternate developmental fates, in a process known as transdifferentiation. The present study analyses the hypothesis that despite being
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55135d27b35713f554cc2b82a6f8a29e
https://hdl.handle.net/10033/317311
https://hdl.handle.net/10033/317311
Autor:
Kfir Molakandov, Mert Icyuz, Henry K. Fortinberry, Juan L. Contreras, Stacie M.J. Bryant, Gene P. Siegal, Hongju Wu
Publikováno v:
Transplantation. 87(6)
Background : Accumulated evidence has shown that insulin producing beta-cells in pancreatic islets have the limited potential to regenerate. Adenoviruses have been widely employed to deliver genes of interest into pancreatic islets. This study was ai