Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kfir Ben-Harush"'
Autor:
Maayan Khayat, Anna Dubrovsky-Gaupp, Matthias Eibauer, Ohad Medalia, Robert D. Goldman, Anne E. Goldman, Kfir Ben-Harush, Yagmur Turgay, K. Tanuj Sapra, Takeshi Shimi
Publikováno v:
Nature. 543:261-264
The nuclear lamina is a fundamental constituent of metazoan nuclei. It is composed mainly of lamins, which are intermediate filament proteins that assemble into a filamentous meshwork, bridging the nuclear envelope and chromatin. Besides providing st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eaaf1c04357f5f3e6b944f9448304c5b
https://doi.org/10.1038/nature21382
https://doi.org/10.1038/nature21382
Autor:
Yosef Gruenbaum, Irena Zingerman-Koladko, Ahmad Salman, Oded Shoseyov, Jan Harapin, Ohad Medalia, Maayan Khayat, Kfir Ben-Harush
Publikováno v:
Journal of the mechanical behavior of biomedical materials. 63
Intermediate filament (IF) proteins are known mainly by their propensity to form viscoelastic filamentous networks within cells. In addition, IF-proteins are essential parts of various biological materials, such as horn and hagfish slime threads, whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44fceee688aceaea9bcdb1a9218b303d
https://pubmed.ncbi.nlm.nih.gov/27341289
https://pubmed.ncbi.nlm.nih.gov/27341289
Publikováno v:
Journal of Structural Biology. 177:106-112
The nuclear lamina is a major structural element of the nucleus and is predominately composed of the intermediate filament lamin proteins. Missense mutations in the human lamins A/C cause a family of laminopathic diseases, with no known mechanistic l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc7a43a117fe5f91411d201c0d5e7ae
https://doi.org/10.1016/j.jsb.2011.10.009
https://doi.org/10.1016/j.jsb.2011.10.009
Autor:
Erin M. Bank, Oren Lotan, Kfir Ben-Harush, Naama Wiesel-Motiuk, Naomi Feinstein, Yosef Gruenbaum, Ohad Medalia, Rachel Barkan
Publikováno v:
Molecular Biology of the Cell
Mutations in human LMNA cause Emery-Dreifuss muscular dystrophy; however, a mechanistic link between the effect of mutations on lamin filament assembly and disease phenotype has not been established. Here we show that changes in lamin filament struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91d9e71f4727f7d847acd8011fe1d84a
http://europepmc.org/articles/PMC3145547
http://europepmc.org/articles/PMC3145547
Publikováno v:
Kinetics and Catalysis. 51:63-68
Solid alkaline metal hydroxides displayed high catalytic activity and full selectivity in the aerobic oxidation of benzylic alcohols in a non-polar medium. The activity of the solid bases, in decreasing order of reactivity, was KOH > NaOH ≫ LiOH. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9d31f6c37d180284ba888c1a63ee130
https://doi.org/10.1134/s0023158410010118
https://doi.org/10.1134/s0023158410010118
Autor:
Katrin Pfleghaar, Francis S. Collins, Robert D. Goldman, Ohad Medalia, Stephen A. Adam, Dorothee Möller, Pekka Taimen, Takeshi Shimi, Harald Herrmann, Anne E. Goldman, Michael R. Erdos, Kfir Ben-Harush
Publikováno v:
Proceedings of the National Academy of Sciences. 106:20788-20793
Numerous mutations in the human A-type lamin gene (LMNA) cause the premature aging disease, progeria. Some of these are located in the α-helical central rod domain required for the polymerization of the nuclear lamins into higher order structures. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af256ac2019603e46e5a16dc4ed65c43
https://doi.org/10.1073/pnas.0911895106
https://doi.org/10.1073/pnas.0911895106
Publikováno v:
Letters in Organic Chemistry. 3:664-667
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37ca981dd16546e83c1dbc8e55158684
https://doi.org/10.2174/157017806778699973
https://doi.org/10.2174/157017806778699973
Autor:
N. Zeytuni, Maxim Levin, Ertan Ozyamak, Kfir Ben-Harush, Tal Moyal, Ashraf Brik, Geula Davidov, Arash Komeili, Raz Zarivach, Yair Gat
Publikováno v:
Proceedings of the National Academy of Sciences. 108
The magnetosome, a biomineralizing organelle within magnetotactic bacteria, allows their navigation along geomagnetic fields. Magnetosomes are membrane-bound compartments containing magnetic nanoparticles and organized into a chain within the cell, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee8b1a3abd1322ff3e3440c346294a9a
https://doi.org/10.1073/pnas.1103367108
https://doi.org/10.1073/pnas.1103367108
Publikováno v:
Journal of cell science. 123(Pt 1)
The cellular landscape rapidly changes throughout the biological processes that transpire within a cell. For example, the cytoskeleton is remodeled within fractions of a second. Therefore, reliable structural analysis of the cell requires approaches
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c11504e109b99d993a13db419cd2719
https://pubmed.ncbi.nlm.nih.gov/20016061
https://pubmed.ncbi.nlm.nih.gov/20016061
Autor:
Ueli Aebi, Naama Wiesel, Yosef Gruenbaum, Daphna Frenkiel-Krispin, Kfir Ben-Harush, Harald Herrmann, Ohad Medalia, Eyal Soreq, Dorothee Moeller
Publikováno v:
Journal of molecular biology. 386(5)
Nuclear lamins are involved in most nuclear activities and are essential for retaining the mechano-elastic properties of the nucleus. They are nuclear intermediate filament (IF) proteins forming a distinct meshwork-like layer adhering to the inner nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71a0b2619ac5cc861491d56809fb0b7
https://pubmed.ncbi.nlm.nih.gov/19109977
https://pubmed.ncbi.nlm.nih.gov/19109977