Zobrazeno 1 - 10
of 541
pro vyhledávání: '"Keyur P Patel"'
Autor:
Kathryn A Kundrod, Mary E Natoli, Megan M Chang, Chelsey A Smith, Sai Paul, Dereq Ogoe, Christopher Goh, Akshaya Santhanaraj, Anthony Price, Karen W Eldin, Keyur P Patel, Ellen Baker, Kathleen M Schmeler, Rebecca Richards-Kortum
Publikováno v:
PLoS ONE, Vol 17, Iss 2, p e0264130 (2022)
The global COVID-19 pandemic has highlighted the need for rapid, accurate and accessible nucleic acid tests to enable timely identification of infected individuals. We optimized a sample-to-answer nucleic acid test for SARS-CoV-2 that provides result
Externí odkaz:
https://doaj.org/article/103431d8ded940dca930d1c41aa32cea
Autor:
Santiago Montes-Moreno, Mark J Routbort, Elijah J Lohman, Bedia A Barkoh, Rashmi Kanagal-Shamanna, Carlos E Bueso-Ramos, Rajesh R Singh, L Jeffrey Medeiros, Raja Luthra, Keyur P Patel
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204218 (2018)
ASXL1 (additional sex combs like 1) is a gene that is mutated in a number of hematological neoplasms. The most common genetic alteration is c.1934dupG p.Gly646fs. Previous publications have shown that ASXL1 mutations have a negative prognostic impact
Externí odkaz:
https://doaj.org/article/211084062a8445818fd012187eafcc83
Autor:
Meenakshi Mehrotra, Dzifa Yawa Duose, Rajesh R Singh, Bedia A Barkoh, Jawad Manekia, Michael A Harmon, Keyur P Patel, Mark J Routbort, L Jeffrey Medeiros, Ignacio I Wistuba, Rajyalakshmi Luthra
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0181968 (2017)
Next generation sequencing based tumor tissue genotyping involves complex workflow and a relatively longer turnaround time. Semiconductor based next generation platforms varied from low throughput Ion PGM to high throughput Ion Proton and Ion S5XL se
Externí odkaz:
https://doaj.org/article/bb549dfe68a64ba9828eeddd3a89200d
Autor:
Amir Mehrvarz Sarshekeh, Shailesh Advani, Michael J Overman, Ganiraju Manyam, Bryan K Kee, David R Fogelman, Arvind Dasari, Kanwal Raghav, Eduardo Vilar, Shanequa Manuel, Imad Shureiqi, Robert A Wolff, Keyur P Patel, Raja Luthra, Kenna Shaw, Cathy Eng, Dipen M Maru, Mark J Routbort, Funda Meric-Bernstam, Scott Kopetz
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173345 (2017)
SMAD4 is an essential mediator in the transforming growth factor-β pathway. Sporadic mutations of SMAD4 are present in 2.1-20.0% of colorectal cancers (CRCs) but data are limited. In this study, we aimed to evaluate clinicopathologic characteristics
Externí odkaz:
https://doaj.org/article/bfd5486e32c44fa5ab5f0b9a3eb57fca
Autor:
Carol J. Nowlen, Molly Daniels, Burak Uzunparmak, Ecaterina E. Ileana Dumbrava, Ying Yuan, Keyur P. Patel, Nadine Rayes, Jacqueline Harkenrider, Chetna Wathoo, Jennifer Veazie, Krystle A. Luna, Wanlin Wang, Chacha Horombe, Milind Javle, Jordi Rodon Ahnert, Timothy A. Yap, Banu Arun, Karen H. Lu, Funda Meric-Bernstam
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Vol 7, Iss 1, Pp 7-17 (2024)
Introduction Genomic profiling is performed in patients with advanced or metastatic cancer, in order to direct cancer treatment, often sequencing tumor-only, without a matched germline comparator. However, because many of the genes analyzed on tumor
Externí odkaz:
https://doaj.org/article/1c82c80e6fbe4a119579d33a7fda0372
Autor:
J. Bryan Iorgulescu, Leah K. Shaw, Asif Rashid, Priya Rao, Sreedhar Mandayam, Keyur P. Patel, Kathleen M. Schmeler, Richard K. Yang, Pavlos Msaouel
Publikováno v:
Current Oncology, Vol 30, Iss 10, Pp 9019-9027 (2023)
Clear cell carcinomas of Müllerian origin have a strong female predominance and only extremely rarely will arise within the kidney, presumably due to ectopic Müllerian embryogenesis. Herein, we report a unique case of metastatic Müllerian type cle
Externí odkaz:
https://doaj.org/article/d574c19ba193436980ddfb595b27cbbc
Autor:
Nicholas J. Short, Muharrem Muftuoglu, Faustine Ong, Lewis Nasr, Walid Macaron, Guillermo Montalban-Bravo, Yesid Alvarado, Mahesh Basyal, Naval Daver, Courtney D. Dinardo, Gautam Borthakur, Nitin Jain, Maro Ohanian, Elias Jabbour, Ghayas C. Issa, Wei Qiao, Xuelin Huang, Rashmi Kanagal-Shamanna, Keyur P. Patel, Prithviraj Bose, Farhad Ravandi, Ricardo Delumpa, Regina Abramova, Guillermo Garcia-Manero, Michael Andreeff, Jorge Cortes, Hagop Kantarjian
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-11 (2023)
Abstract Background Pevonedistat is a first-in-class, small molecular inhibitor of NEDD8-activating enzyme that has clinical activity in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). Preclinical data suggest synergy of pevonedista
Externí odkaz:
https://doaj.org/article/ad7ca09609614d58a1b068a42eba3a40
Autor:
Hong Fang, Sa A. Wang, Joseph D. Khoury, Siba El Hussein, Do Hwan Kim, Mehrnoosh Tashakori, Zhenya Tang, Shaoying Li, Zhihong Hu, Fatima Zahra Jelloul, Keyur P. Patel, Timothy J. McDonnell, Tapan Kadia, L. Jeffrey Medeiros, Wei Wang
Publikováno v:
Haematologica, Vol 107, Iss 9 (2022)
Externí odkaz:
https://doaj.org/article/c122f83278f34519bfac6874db1dedf5
Autor:
Zhuang Zuo, L. Jeffrey Medeiros, Sofia Garces, Mark J. Routbort, Chi Young Ok, Sanam Loghavi, Rashmi Kanagal-Shamanna, Fatima Zahra Jelloul, Guillermo Garcia-Manero, Kelly S. Chien, Keyur P. Patel, Rajyalakshmi Luthra, C. Cameron Yin
Publikováno v:
Biology, Vol 12, Iss 1, p 13 (2022)
It has been reported that gene mutations in SF3B1 and PHF6 are mutually exclusive. However, this observation has never been rigorously assessed. We report the clinicopathologic and molecular genetic features of 21 cases of myeloid neoplasms with doub
Externí odkaz:
https://doaj.org/article/584dd1f056e34ae3afbdf575c030f774
Autor:
Siba El Hussein, L. Jeffrey Medeiros, Kirill A. Lyapichev, Hong Fang, Fatima Zahra Jelloul, Warren Fiskus, Jiansong Chen, Peng Wei, Ellen Schlette, Jie Xu, Shaoying Li, Rashmi Kanagal-Shamanna, Hong Yang, Zhenya Tang, Beenu Thakral, Sanam Loghavi, Nitin Jain, Philip A. Thompson, Alessandra Ferrajoli, William G. Wierda, Elias Jabbour, Keyur P. Patel, Bouthaina S. Dabaja, Kapil N. Bhalla, Joseph D. Khoury
Publikováno v:
Pathology. 55:514-524
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::399a979eb7c2fc1b1ebba02db4cd3898
https://doi.org/10.1016/j.pathol.2022.12.354
https://doi.org/10.1016/j.pathol.2022.12.354