Zobrazeno 1 - 10
of 284
pro vyhledávání: '"Keyue Ding"'
Autor:
Zhou Zhou, Xia Tang, Wen Chen, Qianlong Chen, Bo Ye, Angad S. Johar, Iftikhar J. Kullo, Keyue Ding
Publikováno v:
HGG Advances, Vol 5, Iss 1, Pp 100258- (2024)
Summary: Ebstein’s anomaly, a rare congenital heart disease, is distinguished by the failure of embryological delamination of the tricuspid valve leaflets from the underlying primitive right ventricle myocardium. Gaining insight into the genetic ba
Externí odkaz:
https://doaj.org/article/f1cd320f51a440a9b19942ce3542d159
Autor:
Zhou Zhou, Xumei Huang, Xia Tang, Wen Chen, Qianlong Chen, Chaohui Zhang, Yuxin Li, Dachun Zhao, Zhe Zheng, Shengshou Hu, Jikui Wang, Iftikhar J. Kullo, Keyue Ding
Publikováno v:
HGG Advances, Vol 4, Iss 4, Pp 100227- (2023)
Summary: Ebstein’s anomaly is a rare congenital heart disease characterized by tricuspid valve downward displacement and is associated with additional cardiac phenotypes such as left ventricle non-compaction. The genetic basis of Ebstein’s anomal
Externí odkaz:
https://doaj.org/article/36284c9c22af49329b800ae08b44da6f
Autor:
Kaleem Atchia, France-Hélène Joncas, Lily Summers Trasiewicz, Wei Phin Tan, Keyue Ding, Brant A. Inman, Paul Toren
Publikováno v:
Société Internationale d’Urologie Journal, Vol 3, Iss 2, Pp 56-61 (2022)
BackgroundFollicle-stimulating hormone (FSH) dysregulation plays a potential role in prostate cancer progression. The objective of this study was to evaluate whether higher FSH levels during androgen deprivation therapy (ADT) for recurrent prostate c
Externí odkaz:
https://doaj.org/article/c6d5d6a3d9a147708ed505ea15760e66
Publikováno v:
Genes and Diseases, Vol 8, Iss 2, Pp 232-240 (2021)
Vesicle Protein Sorting 35 (VPS35) is a novel oncogene that promotes tumor growth through the PI3K/AKT signaling in hepatocellular carcinoma (HCC). However, the role of VPS35 in HCC metastasis and the underlying mechanisms remain largely unclear. In
Externí odkaz:
https://doaj.org/article/b4809dca3f8247d1984d72def20894f7
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 10, Iss 5, Pp n/a-n/a (2022)
Abstract Background Neurodevelopmental disorders, a group of early‐onset neurological disorders with significant clinical and genetic heterogeneity, remain a diagnostic challenge for clinical genetic evaluation. Therefore, we assessed the diagnosti
Externí odkaz:
https://doaj.org/article/0b1fffc84b004570ac46c671517799f3
Autor:
Chaohui Zhang, Yuxin Li, Jiaheng Cao, Beibei Yu, Kaiyue Zhang, Ke Li, Xinhui Xu, Zhikun Guo, Yinming Liang, Xiao Yang, Zhongzhou Yang, Yunfu Sun, Vesa Kaartinen, Keyue Ding, Jikui Wang
Publikováno v:
Open Biology, Vol 11, Iss 6 (2021)
Smoothened is a key receptor of the hedgehog pathway, but the roles of Smoothened in cardiac development remain incompletely understood. In this study, we found that the conditional knockout of Smoothened from the mesoderm impaired the development of
Externí odkaz:
https://doaj.org/article/30c993ac5e5e41f98bfff65a7bfbed54
Autor:
Shengran Wang, Xia Tang, Litao Qin, Weili Shi, Shasha Bian, Zhaokun Wang, Qingqing Wang, Xin Wang, Jianqin Gu, Bingtao Hao, Keyue Ding, Shixiu Liao
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Accumulating evidence suggests that circular RNAs (circRNAs)—miRNA–mRNA ceRNA regulatory network—may play an important role in neurological disorders, such as Alzheimer’s disease (AD). Interestingly, neuropathological changes that closely res
Externí odkaz:
https://doaj.org/article/b231609f9fd34f4a8b3b160434770987
Comparison of error correction algorithms for Ion Torrent PGM data: application to hepatitis B virus
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Ion Torrent Personal Genome Machine (PGM) technology is a mid-length read, low-cost and high-speed next-generation sequencing platform with a relatively high insertion and deletion (indel) error rate. A full systematic assessment of the effe
Externí odkaz:
https://doaj.org/article/3ea364f13c72441ca774d4bcc1642163
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150465 (2016)
RNA editing is one of the post- or co-transcriptional processes that can lead to amino acid substitutions in protein sequences, alternative pre-mRNA splicing, and changes in gene expression levels. Although several methods have been suggested to iden
Externí odkaz:
https://doaj.org/article/4e79e4e5151d4f08bee229971bfcfb41
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 7, Pp 1457-1462 (2006)
Genomic regions that influence LDL particle size in African Americans are not known. We performed family-based linkage analyses to identify genomic regions that influence LDL particle size and also exert pleiotropic effects on two closely related lip
Externí odkaz:
https://doaj.org/article/3288a69c8536478aa5066e02514d97ea