The Role of Regulatory T Cell in Nontypeable Haemophilus influenzae-Induced Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Autor: Xuewa Guan, Yanjiao Lu, Guoqiang Wang, Peter Gibson, Fang Chen, Keyong Fang, Ziyan Wang, Zhiqiang Pang, Yingqiao Guo, Junying Lu, Yuze Yuan, Nan Ran, Fang Wang

Publikováno v: Mediators of Inflammation, Vol 2018 (2018)

Chronic obstructive pulmonary disease (COPD) is associated with irreversible persistent airflow limitation and enhanced inflammation. The episodes of acute exacerbation (AECOPD) largely depend on the colonized pathogens such as nontypeable Haemophilu

Externí odkaz: https://doaj.org/article/e6bac90a15b9482cb8d51f8157b50886

Advanced Role of Neutrophils in Common Respiratory Diseases

Autor: Jinping Liu, Zhiqiang Pang, Guoqiang Wang, Xuewa Guan, Keyong Fang, Ziyan Wang, Fang Wang

Publikováno v: Journal of Immunology Research, Vol 2017 (2017)

Respiratory diseases, always being a threat towards the health of people all over the world, are most tightly associated with immune system. Neutrophils serve as an important component of immune defense barrier linking innate and adaptive immunity. T

Externí odkaz: https://doaj.org/article/5204eb51d4a348079121f7793d3b99ae

Anti-Inflammatory Effect of Columbianetin on Lipopolysaccharide-Stimulated Human Peripheral Blood Mononuclear Cells

Autor: Jingtong Zheng, Fang Wang, Ruipeng Zheng, Xuewa Guan, Keyong Fang, Shiji Wang, Zhongmin Liu, Lingxin Xiong, Chao Zhang, Guoqiang Wang, Junying Lu

Publikováno v: Mediators of Inflammation, Vol 2018 (2018)
Mediators of Inflammation

Dysregulated inflammation is increasingly considered as the main cause of many diseases on which NOD1/NF-κB pathway plays an important role. Columbianetin (CBT) is derived from the root of the Chinese herb Radix Angelicae Pubescentis for treating in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48c02c1dcb1b87536122640ce11749cb
https://doi.org/10.1155/2018/9191743

Inhibitory Effect of Methotrexate on Rheumatoid Arthritis Inflammation and Comprehensive Metabolomics Analysis Using Ultra-Performance Liquid Chromatography-Quadrupole Time of Flight-Mass Spectrometry (UPLC-Q/TOF-MS)

Autor: Guoqiang Wang, Zhiqiang Pang, Ziyan Wang, Hongqiang Lin, Nan Ran, Yuze Yuan, Jinping Liu, Xuewa Guan, Fang Wang, Keyong Fang

Publikováno v: International Journal of Molecular Sciences
Volume 19
Issue 10
International Journal of Molecular Sciences, Vol 19, Iss 10, p 2894 (2018)

Rheumatoid arthritis (RA) is a common autoimmune disease. The inflammation in joint tissue and system endanger the human health seriously. Methotrexate have exhibited a satisfactory therapeutic effect in clinical practice. The aim of this research wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::345898270915fd5e85e63bd1b3545eae
https://pubmed.ncbi.nlm.nih.gov/30249062

Obesity-Related Asthma: Immune Regulation and Potential Targeted Therapies

Autor: Xuewa Guan, Guoqiang Wang, Junying Lu, Lingxin Xiong, Ziyan Wang, Nan Ran, Jie Ma, Ruipeng Zheng, Yuze Yuan, Chao Zhang, Yingqiao Guo, Keyong Fang, Fang Wang, Jingtong Zheng, Zhiqiang Pang

Publikováno v: Journal of Immunology Research, Vol 2018 (2018)
Journal of Immunology Research

Obesity, one of the most severe public health problems of the 21st century, is a common metabolic syndrome due to excess body fat. The incidence and severity of obesity-related asthma have undergone a dramatic increase. Because obesity-related asthma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afb214a72150b40d3b6b9884a4275b2a
https://pubmed.ncbi.nlm.nih.gov/30050954