Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Keyla S. G. de Sá"'
Autor:
Keyla S. G. de Sá, Luana A. Amaral, Tamara S. Rodrigues, Adriene Y. Ishimoto, Warrison A. C. de Andrade, Leticia de Almeida, Felipe Freitas-Castro, Sabrina S. Batah, Sergio C. Oliveira, Mônica T. Pastorello, Alexandre T. Fabro, Dario S. Zamboni
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Here, de Sá et al. show that Gasdermin-D is transiently activated in Leishmania-infected macrophages and promotes NLRP3 inflammasome activation, but not cell death. Gasdermin-D is cleaved into a noncanonical fragment, indicating that Leishmania subv
Externí odkaz:
https://doaj.org/article/1a83c20a305e4205a732e3e7fc4d594d
Autor:
Keyla S G de Sá, Luana A Amaral, Tamara S Rodrigues, Camila C S Caetano, Amanda Becerra, Sabrina S Batah, Felipe T Lopes, Isadora M de Oliveira, Letícia S Lopes, Leticia Almeida, Caroline M Mota, Samuel Oliveira, Danilo T Wada, Marcel Koenigkam-Santos, Ronaldo B Martins, Roberta R C Rosales, Eurico Arruda, Alexandre T Fabro, Dario S Zamboni
Publikováno v:
PLoS Pathogens, Vol 20, Iss 6, p e1012222 (2024)
COVID-19 has affected more than half a billion people worldwide, with more than 6.3 million deaths, but the pathophysiological mechanisms involved in lethal cases and the host determinants that determine the different clinical outcomes are still uncl
Externí odkaz:
https://doaj.org/article/eaf6eb7e94f3467683d58b1f62c481e8
Autor:
Letícia de Almeida, Alexandre L. N. da Silva, Tamara S. Rodrigues, Samuel Oliveira, Adriene Y. Ishimoto, Amanda A. Seribelli, Amanda Becerra, Warrison A. Andrade, Marco A. Ataide, Camila C. S. Caetano, Keyla S. G. de Sá, Natália Pelisson, Ronaldo B. Martins, Juliano de Paula Souza, Eurico Arruda, Sabrina S. Batah, Ricardo Castro, Fabiani G. Frantz, Fernando Q. Cunha, Thiago M. Cunha, Alexandre T. Fabro, Larissa D. Cunha, Paulo Louzada-Junior, Rene D. R. de Oliveira, Dario S. Zamboni
Publikováno v:
Science advances. 8(37)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces mild or asymptomatic COVID-19 in most cases, but some patients develop an excessive inflammatory process that can be fatal. As the NLRP3 inflammasome and additional inflammasomes ar