Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Keying Che"'
Autor:
Yue Wang, Hanbing Wang, Tao Shi, Xueru Song, Xin Zhang, Yue Zhang, Xuan Wang, Keying Che, Yuting Luo, Lixia Yu, Baorui Liu, Jia Wei
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 9, Pp 2170-2187 (2024)
Abstract The CLDN18-ARHGAP fusion gene is an oncogenic driver newly discovered in gastric cancer. It was detected in 9% (8/87) of gastric cancer patients in our center. An immunogenic peptide specifically targeting CLDN18-ARHGAP fusion gene was gener
Externí odkaz:
https://doaj.org/article/0f5c4a33287149c9a3c9e1183b00e088
Macrophages reprogramming improves immunotherapy of IL-33 in peritoneal metastasis of gastric cancer
Autor:
Keying Che, Yuting Luo, Xueru Song, Zhe Yang, Hanbing Wang, Tao Shi, Yue Wang, Xuan Wang, Hongyan Wu, Lixia Yu, Baorui Liu, Jia Wei
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 2, Pp 251-266 (2024)
Abstract Peritoneal metastasis (PM) has a suppressive tumor immune microenvironment (TIME) that limits the effects of immunotherapy. This study aimed to investigate the immunomodulatory effects of intraperitoneal administration of IL-33, a cytokine t
Externí odkaz:
https://doaj.org/article/5d8eb88aaa0a4ecda569de885caf27d7
Publikováno v:
Cancer Medicine, Vol 9, Iss 19, Pp 7137-7150 (2020)
Abstract Background The survival benefits of perioperative chemoradiotherapy (PCRT) and perioperative chemotherapy (PCT) for resectable gastric cancer (GC) patients remain unclear. This study aimed to compare the effects of PCRT and PCT in patients w
Externí odkaz:
https://doaj.org/article/1d0a9ec36c014b0f8f033c5aeef988cd
Autor:
Yue Wang, Xuan Wang, Qin Liu, Baorui Liu, Jia Wei, Tao Shi, Yipeng Zhang, Yunfeng Pan, Hanbing Wang, Yuting Luo, Kaijie Liang, Fangcen Liu, Keying Che, Lixia Yu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/bd4bc07953cb41c4b65b733a61583ff2
Autor:
Fangcen Liu, Fangfang Zhong, Huan Wu, Keying Che, Jiaochun Shi, Nandie Wu, Yao Fu, Yue Wang, Jing Hu, Xiaoping Qian, Xiangshan Fan, Weifeng Wang, Jia Wei
Publikováno v:
The Oncologist. 28:e136-e144
Microsatellite instability (MSI) has emerged as an important predictor of sensitivity for immunotherapy-based strategies. β-2-Microglobulin (B2M) contains microsatellites within the coding regions and is prone to somatic changes in MSI/mismatch repa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c82ae9c362562de03f3c541c5ca2410a
https://doi.org/10.1093/oncolo/oyac268
https://doi.org/10.1093/oncolo/oyac268
Autor:
Jia Wei, Baorui Liu, Lixia Yu, Qin Liu, Ju Yang, Fangcen Liu, Yunfeng Pan, Xuan Wang, Keying Che, Yuting Luo, Kaijie Liang, Xiaoyu Zhou, Hanbing Wang, Xueru Song, Yue Wang, Yipeng Zhang, Tao Shi
Supplementary Data from DKK1 Promotes Tumor Immune Evasion and Impedes Anti–PD-1 Treatment by Inducing Immunosuppressive Macrophages in Gastric Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f3d5cbc94863dcf5b825bd902141ecf
https://doi.org/10.1158/2326-6066.22545938
https://doi.org/10.1158/2326-6066.22545938
Autor:
Jia Wei, Baorui Liu, Lixia Yu, Qin Liu, Ju Yang, Fangcen Liu, Yunfeng Pan, Xuan Wang, Keying Che, Yuting Luo, Kaijie Liang, Xiaoyu Zhou, Hanbing Wang, Xueru Song, Yue Wang, Yipeng Zhang, Tao Shi
Tumor-associated macrophages (TAM) have key functions in promoting a suppressive tumor immune microenvironment (TIME) and immune evasion, which largely limit treatment effects of immune-checkpoint inhibitors (ICI) in different cancers, including gast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a3afb6eb16540a6d490ae15c4e1208
https://doi.org/10.1158/2326-6066.c.6551060
https://doi.org/10.1158/2326-6066.c.6551060
Publikováno v:
Cancer Research. 83:2878-2878
Immunosuppressive neutrophils are identified as a specialized heterogeneous population in cancer patients that accelerate tumor progression. However, the developmental stage and the source of this population remain elusive. To address this issue, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc6d2d5f70b1269b3c07100bad4e34b0
https://doi.org/10.1158/1538-7445.am2023-2878
https://doi.org/10.1158/1538-7445.am2023-2878
Autor:
Bo Xu, Fangjun Chen, Xin Zhang, Zhongda Wang, Keying Che, Nandie Wu, Lixia Yu, Xiangshan Fan, Baorui Liu, Jia Wei
Publikováno v:
Cancers; Volume 14; Issue 11; Pages: 2758
T cell-based immunotherapy has led to many breakthroughs in the treatment of solid tumors. In this study, we found that membrane protein Claudin18.2 was a promising antigen in T cell-based immunotherapy for gastric cancer (GC). Firstly, we identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fffa4a987a2230556164439805b257e5
Publikováno v:
Cancer Medicine
Cancer Medicine, Vol 9, Iss 19, Pp 7137-7150 (2020)
Cancer Medicine, Vol 9, Iss 19, Pp 7137-7150 (2020)
Background The survival benefits of perioperative chemoradiotherapy (PCRT) and perioperative chemotherapy (PCT) for resectable gastric cancer (GC) patients remain unclear. This study aimed to compare the effects of PCRT and PCT in patients with resec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40230544c19028d407593250ecc427ee
http://europepmc.org/articles/PMC7541150
http://europepmc.org/articles/PMC7541150