Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Itaconate stabilizes CPT1a to enhance lipid utilization during inflammation.

Autor: Mainali R; Department of Pathology, Section on Comparative Medicine, Wake Forest School of Medicine, Winston Salem, United States., Buechler N; Department of Pathology, Section on Comparative Medicine, Wake Forest School of Medicine, Winston Salem, United States., Otero C; Department of Pathology, Section on Comparative Medicine, Wake Forest School of Medicine, Winston Salem, United States., Edwards L; Department of Pathology, Section on Comparative Medicine, Wake Forest School of Medicine, Winston Salem, United States., Key CC; Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston Salem, United States., Furdui C; Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston Salem, United States., Quinn MA; Department of Pathology, Section on Comparative Medicine, Wake Forest School of Medicine, Winston Salem, United States.; Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston Salem, United States.

Publikováno v: ELife [Elife] 2024 Feb 02; Vol. 12. Date of Electronic Publication: 2024 Feb 02.

Redox integration of signaling and metabolism in a head and neck cancer model of radiation resistance using COSM ^RO .

Autor: Ji Z; Division of Radiologic Sciences - Center for Bioinformatics and Systems Biology, Wake Forest School of Medicine, Winston-Salem, NC, United States., Moore J; Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, United States., Devarie-Baez NO; Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, United States., Lewis J; The Parker H. Petit Institute of Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA, United States.; Department of Internal Medicine, Section on Hematology and Oncology, Wake Forest School of Medicine, Winston-Salem, NC, United States., Wu H; Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, United States., Shukla K; Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, United States., Lopez EIS; Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, United States., Vitvitsky V; The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Emory School of Medicine, Atlanta, GA, United States., Key CC; Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, United States., Porosnicu M; Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI, United States., Kemp ML; The Parker H. Petit Institute of Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA, United States.; Department of Internal Medicine, Section on Hematology and Oncology, Wake Forest School of Medicine, Winston-Salem, NC, United States., Banerjee R; The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Emory School of Medicine, Atlanta, GA, United States., Parks JS; Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, United States., Tsang AW; Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, United States., Zhou X; Division of Radiologic Sciences - Center for Bioinformatics and Systems Biology, Wake Forest School of Medicine, Winston-Salem, NC, United States., Furdui CM; Department of Internal Medicine, Section on Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, United States.

Publikováno v: Frontiers in oncology [Front Oncol] 2023 Jan 04; Vol. 12, pp. 946320. Date of Electronic Publication: 2023 Jan 04 (Print Publication: 2022).

Keratinocyte-associated protein 3 plays a role in body weight and adiposity with differential effects in males and females.

Autor: Szalanczy AM; Department of Internal Medicine, School of Medicine, Wake Forest University, Winston Salem, NC, United States., Goff E; Department of Internal Medicine, School of Medicine, Wake Forest University, Winston Salem, NC, United States., Seshie O; Department of Internal Medicine, School of Medicine, Wake Forest University, Winston Salem, NC, United States., Deal A; Department of Internal Medicine, School of Medicine, Wake Forest University, Winston Salem, NC, United States., Grzybowski M; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, United States., Klotz J; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, United States., Chuang Key CC; Department of Internal Medicine, School of Medicine, Wake Forest University, Winston Salem, NC, United States., Geurts AM; Department of Physiology, Medical College of Wisconsin, Milwaukee, WI, United States., Solberg Woods LC; Department of Internal Medicine, School of Medicine, Wake Forest University, Winston Salem, NC, United States.

Publikováno v: Frontiers in genetics [Front Genet] 2022 Sep 21; Vol. 13, pp. 942574. Date of Electronic Publication: 2022 Sep 21 (Print Publication: 2022).

Exploiting three-dimensional human hepatic constructs to investigate the impact of rs174537 on fatty acid metabolism.

Autor: Kirk LM; Department of Biomedical Engineering, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.; Virginia Tech - Wake Forest University, School of Biomedical Engineering and Sciences, Blacksburg, Virginia, United States of America., Waits CMK; Department of Biomedical Engineering, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.; Virginia Tech - Wake Forest University, School of Biomedical Engineering and Sciences, Blacksburg, Virginia, United States of America., Bashore AC; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York, United States of America.; Department of Internal Medicine, Section of Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America., Dosso B; Department of Integrative Physiology & Pharmacology, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America., Meyers AK; Department of Internal Medicine, Section of Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.; Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America., Renaldo AC; Department of Biomedical Engineering, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.; Virginia Tech - Wake Forest University, School of Biomedical Engineering and Sciences, Blacksburg, Virginia, United States of America., DePalma TJ; Department of Biomedical Engineering, The Ohio State University, Columbus, Ohio, United States of America., Simms KN; Department of Biomedical Engineering, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.; Virginia Tech - Wake Forest University, School of Biomedical Engineering and Sciences, Blacksburg, Virginia, United States of America., Hauser N; Department of Biomedical Engineering, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.; Virginia Tech - Wake Forest University, School of Biomedical Engineering and Sciences, Blacksburg, Virginia, United States of America., Chuang Key CC; Department of Internal Medicine, Section of Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America., McCall CE; Department of Internal Medicine, Section of Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America., Parks JS; Department of Internal Medicine, Section of Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America., Sergeant S; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America., Langefeld CD; Department of Biostatistics and Data Science, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.; Center for Precision Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America., Skardal A; Department of Biomedical Engineering, The Ohio State University, Columbus, Ohio, United States of America., Rahbar E; Department of Biomedical Engineering, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.; Virginia Tech - Wake Forest University, School of Biomedical Engineering and Sciences, Blacksburg, Virginia, United States of America.; Center for Precision Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.

Publikováno v: PloS one [PLoS One] 2022 Jan 20; Vol. 17 (1), pp. e0262173. Date of Electronic Publication: 2022 Jan 20 (Print Publication: 2022).