Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Kexiang Yan"'
Autor:
Ling Han, Yixiao Gan, Juan Du, Yao Hu, Yanwen Chen, Qiong Huang, Zhenghua Zhang, Nikhil Yawalkar, Kexiang Yan, Zhicheng Wang
Publikováno v:
Journal of Dermatological Treatment, Vol 35, Iss 1 (2024)
Background Numerous studies have linked the inflammatory pathway in psoriasis and metabolic disease, while no specific marker defined it. It is worth exploring the association of β2-microglobulin (β2M) in psoriasis severity and comorbidities.Object
Externí odkaz:
https://doaj.org/article/3d26d20005334740bf3fb9e1cda60de3
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background Psoriasis is an inflammatory disease mediated by helper T (Th)17 and Th1 cells. MicroRNA-125a (miR-125a) is reduced in the lesional skin of psoriatic patients. However, the mechanism by which miR-125a participates in psoriasis rem
Externí odkaz:
https://doaj.org/article/822b620b009e4ad6a1e0ec8a0885f94e
Autor:
Hua Zhang, Miao Chen, Ran Cui, Xia Li, Kexiang Yan, Lihong Chen, Zhenghua Zhang, Ning Yu, Xinling Bi, Hui Deng, Yangfeng Ding, Qiong Huang, Sheng-Ming Dai, Lishao Guo
Publikováno v:
Chinese Medical Journal, Vol 136, Iss 12, Pp 1439-1447 (2023)
Abstract. Background:. Reports on the prevalence of psoriatic arthritis (PsA) among Chinese patients with psoriasis are very limited. This study, conducted by rheumatologists, estimated the prevalence of PsA in a large number of Chinese patients with
Externí odkaz:
https://doaj.org/article/50b11ef378ef463a901efba396ddd959
Autor:
Simon Bossart, S. Morteza Seyed Jafari, Kristine Heidemeyer, Kexiang Yan, Laurence Feldmeyer, Luca Borradori, Nikhil Yawalkar
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Interleukin-1 (IL-1)-blocking therapies are effective in reducing disease severity and inflammation in Schnitzler syndrome. Here, we present a patient with Schnitzler syndrome treated successfully using canakinumab for over 10 years. Complete clinica
Externí odkaz:
https://doaj.org/article/d59c288ad6344588b7baf94ceaca6d18
Autor:
Bing Wang, Hui Deng, Yao Hu, Ling Han, Qiong Huang, Xu Fang, Ke Yang, Siyuan Wu, Zhizhong Zheng, Nikhil Yawalkar, Zhenghua Zhang, Kexiang Yan
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-9 (2022)
Abstract Background Methotrexate (MTX) has a protective effect against cardiovascular diseases (CVD), but the mechanism is unclear. Objective To investigate the effect of MTX on lipid profiles and the difference between psoriasis without arthritis (P
Externí odkaz:
https://doaj.org/article/deea592338d74041bae74c50810d71db
Autor:
Jie Zhu, Ling Han, Ruilai Liu, Zhenghua Zhang, Qiong Huang, Xu Fang, Ke Yang, Guiqin Huang, Zhizhong Zheng, Nikhil Yawalkar, Hui Deng, Kexiang Yan
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-9 (2021)
Abstract Background Biomarkers for distinguishing psoriatic arthritis (PsA) from psoriasis without arthritis (PsO) are still lacking. Methods We applied isobaric tags for relative and absolute quantification (iTRAQ) and LC–MS/MS to analyze the prot
Externí odkaz:
https://doaj.org/article/f0097910dbef450791fae45374d704ee
Autor:
Wenghong Wong, Yike Huang, Zhuanbin Wu, Yu Kong, Jing Luan, Qiaoan Zhang, Jiewen Pan, Kexiang Yan, Zhenghua Zhang
Publikováno v:
Biological Research, Vol 54, Iss 1, Pp 1-10 (2021)
Abstract Background The MVD gene mutations are identified in porokeratosis, which is considered a skin-specific autoinflammatory keratinization disease. However, the biological function of MVD gene remains largely unknown. Therefore, we analyzed the
Externí odkaz:
https://doaj.org/article/01fecf8e92bb4a899d84f16c171d892b
Autor:
Huang Qiong, Ling Han, Nanxue Zhang, Huyan Chen, Kexiang Yan, Zhenghua Zhang, Ying Ma, Jinhua Xu
Publikováno v:
BMC Immunology, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background The anti-inflammatory effect of glycyrrhizin has been widely recognized, while the specific mechanism of glycyrrhizin in psoriasis remains poorly understood. Results In the imiquimod-induced mouse model of psoriasis (IMD), we foun
Externí odkaz:
https://doaj.org/article/06d8457a50a448b4a05dc56d351d763e
Autor:
Jie Zhu, Zhicheng Wang, Lu Tao, Ling Han, Qiong Huang, Xu Fang, Ke Yang, Guiqin Huang, Zhizhong Zheng, Nikhil Yawalkar, Zhenghua Zhang, Kexiang Yan
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
AimsTo assess whether MTHFR rs1801131 and rs1801133 SNPs are associated with concomitant psoriatic arthritis (PsA) and investigate the efficacy and hepatotoxicity of MTX in patients with psoriasis in the Han Chinese population.MethodsThis prospective
Externí odkaz:
https://doaj.org/article/f37798dda99640ed9a99cffaa1aed22d
Autor:
Jingxiu Chai, Jie Ren, Kexiang Yan, Feng Xu, Ying Ma, Xiaohua Zhu, Fang Yan, Yongsheng Yang, Chaoying Gu, Jinfeng Wu, Jinhua Xu
Publikováno v:
Traditional Medicine and Modern Medicine, Vol 2, Iss 4, Pp 179-183 (2019)
Objective: To observe the efficacy and safety of Lishi Oral Liquid (LOL), a Chinese herbs formula, combined with levocetirizine, an antihistamine drug, in patients with damp-heat atopic dermatitis (AD). Methods: A randomized double-blind placebo-cont
Externí odkaz:
https://doaj.org/article/8ed2a75894b9410ea76035cd942ea351