Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Kexi Yi"'
Autor:
Xing Duan, Yizeng Li, Kexi Yi, Fengli Guo, HaiYang Wang, Pei-Hsun Wu, Jing Yang, Devin B. Mair, Edwin Angelo Morales, Petr Kalab, Denis Wirtz, Sean X. Sun, Rong Li
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Mammalian oocytes divide asymmetrically during meiotic maturation. Here, the authors show that spindle movement away from oocyte center depends on actin filaments nucleated from the spindle periphery pushing against surrounding mitochondria, which po
Externí odkaz:
https://doaj.org/article/6a3dff5293d84b4c8302fd9120483af3
Autor:
Nicole L Nuckolls, Anthony C Mok, Jeffrey J Lange, Kexi Yi, Tejbir S Kandola, Andrew M Hunn, Scott McCroskey, Julia L Snyder, María Angélica Bravo Núñez, Melainia McClain, Sean A McKinney, Christopher Wood, Randal Halfmann, Sarah E Zanders
Publikováno v:
eLife, Vol 9 (2020)
Meiotic drivers are parasitic loci that force their own transmission into greater than half of the offspring of a heterozygote. Many drivers have been identified, but their molecular mechanisms are largely unknown. The wtf4 gene is a meiotic driver i
Externí odkaz:
https://doaj.org/article/1560ca6d7fc8488d95b7f94f13bf5508
Publikováno v:
PLoS Genetics, Vol 15, Iss 5, p e1008161 (2019)
During early meiotic prophase, homologous chromosomes are connected along their entire lengths by a proteinaceous tripartite structure known as the synaptonemal complex (SC). Although the components that comprise the SC are predominantly studied in t
Externí odkaz:
https://doaj.org/article/506eb29bc2d94b8ca89224c89a8d63bf
Publikováno v:
Developmental Biology. 482:17-27
Spermatogenesis is a dynamic process of cellular differentiation that generates the mature spermatozoa required for reproduction. Errors that arise during this process can lead to sterility due to low sperm counts and malformed or immotile sperm. Whi
Autor:
Luke Olsen, Michaella Levy, J. Kyle Medley, Huzaifa Hassan, Brandon Miller, Richard Alexander, Emma Wilcock, Kexi Yi, Laurence Florens, Kyle Weaver, Sean A. McKinney, Robert Peuß, Jenna Persons, Alexander Kenzior, Ernesto Maldonado, Kym Delventhal, Andrew Gluesenkamp, Edward Mager, David Coughlin, Nicolas Rohner
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Physical inactivity is a scourge to human health, promoting metabolic disease and muscle wasting. Interestingly, multiple ecological niches have relaxed investment into physical activity, providing an evolutionary perspective into the effect of adapt
Autor:
Luke Olsen, Michaella Levy, J Kyle Medley, Huzaifa Hassan, Richard Alexander, Emma Wilcock, Kexi Yi, Laurence Florens, Sean McKinney, Robert Peuß, Jenna Persons, Alexander Kenzior, Ernesto Maldonado, Andrew Gluesenkamp, Edward Mager, David Coughlin, Nicolas Rohner
Physical inactivity – specifically the lack of moderate-to-vigorous activity – is a scourge to human health, promoting metabolic disease and muscle wasting. Interestingly, multiple ecological niches have relaxed investment into physical activity,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::763e2bedf5a90804bdd8d64489246865
https://doi.org/10.1101/2022.03.12.484091
https://doi.org/10.1101/2022.03.12.484091
Publikováno v:
Dev Biol
In cilia and flagella, dyneins form complexes which give rise to the inner and outer axonemal arms. Defects in the dynein arms are the leading cause of primary ciliary dyskinesia (PCD), which is characterized by chronic respiratory infections, situs
Autor:
Pei Hsun Wu, Sean X. Sun, Rong Li, Devin B. Mair, Petr Kalab, Kexi Yi, Xing Duan, Hai Yang Wang, Fengli Guo, Yizeng Li, Edwin Angelo Morales, Jing Yang, Denis Wirtz
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications
Migration of meiosis-I (MI) spindle from the cell center to a sub-cortical location is a critical step for mouse oocytes to undergo asymmetric meiotic cell division. In this study, we investigate the mechanism by which formin-2 (FMN2) orchestrates th
Autor:
HaiYang, Wang, Jinrong, Hu, Kexi, Yi, Zhiming, Ma, XinJie, Song, Yaelim, Lee, Petr, Kalab, Alexander D, Bershadsky, Yansong, Miao, Rong, Li
Publikováno v:
SSRN Electronic Journal.
The first asymmetric meiotic cell divisions in mouse oocytes are driven by formin 2 (FMN2)-nucleated actin polymerization around the spindle. In this study, we investigated how FMN2 is recruited to the spindle peripheral ER and how its activity is re
Autor:
Fengli Guo, Alejandro Sánchez Alvarado, Tari Parmely, Leonid Kruglyak, Xia Zhao, Kexi Yi, Melainia McClain, Jay R. Unruh, Longhua Guo, Brian D. Slaughter
Publikováno v:
Journal of Visualized Experiments.
Accessibility to germ cells allows the study of germ cell development, meiosis, and recombination. The sexual biotype of the freshwater planarian, Schmidtea mediterranea, is a powerful invertebrate model to study the epigenetic specification of germ