Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kewa Mou"'
Autor:
Li Li, Sashi Nadanaciva, Zdenek Berger, Wei Shen, Katrina Paumier, Joel Schwartz, Kewa Mou, Paula Loos, Anthony J Milici, John Dunlop, Warren D Hirst
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e85815 (2013)
Parkinson's disease (PD) is the second most common neurodegenerative disease. A key pathological feature of PD is Lewy bodies, of which the major protein component is α-synuclein (α-syn). Human genetic studies have shown that mutations (A53T, A30P,
Externí odkaz:
https://doaj.org/article/d66a11a109554bf685a5e666188f4884
Autor:
John Dunlop, Wei Shen, Zdenek Berger, Kewa Mou, Katrina L. Paumier, Li Li, Warren D. Hirst, Anastasia G. Henry
Publikováno v:
Journal of Neurochemistry. 129:884-894
Aggregate-prone mutant proteins, such as α-synuclein and huntingtin, play a prominent role in the pathogenesis of various neurodegenerative disorders; thus, it has been hypothesized that reducing the aggregate-prone proteins may be a beneficial ther
Autor:
Kewa Mou, Anastasia G. Henry, Harry Samaroo, Yi Chen, Soheil Aghamohammadzadeh, Warren D. Hirst, Elie Needle
Publikováno v:
Human molecular genetics. 24(21)
Lysosomal dysfunction plays a central role in the pathogenesis of several neurodegenerative disorders, including Parkinson's disease (PD). Several genes linked to genetic forms of PD, including leucine-rich repeat kinase 2 (LRRK2), functionally conve
Publikováno v:
The Journal of Comparative Neurology. 402:129-139
The neurotrophins brain-derived neurotrophin (BDNF) and neurotrophin-3 (NT-3) synergistically enhance survival of spiral ganglion neurons such that simultaneous exposure to both compounds produces a larger response than would be expected from their i
Publikováno v:
The Journal of Comparative Neurology. 386:529-539
Neurotrophins have profound effects on the development and maintenance of neurons that compose the VIIIth cranial nerve. In the auditory division of the nerve, brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3) have been localized to
Autor:
Michael Aaron Brodney, Kevin Atchison, Yao Zhang, Cheng Chang, Leslie R. Pustilnik, Yasong Lu, Sandra J. Engle, Stephen Noell, Kewa Mou, Ashley Robshaw, David Riddell, Charles E. Nolan, Christine E. Oborski
Publikováno v:
Alzheimer's & Dementia. 9
Autor:
Warren D. Hirst, Katrina L. Paumier, John Dunlop, Kewa Mou, Joel W. Schwartz, Wei Shen, Anthony J. Milici, Paula Loos, Sashi Nadanaciva, Zdenek Berger, Li Li
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e85815 (2013)
PLoS ONE
PLoS ONE
Parkinson’s disease (PD) is the second most common neurodegenerative disease. A key pathological feature of PD is Lewy bodies, of which the major protein component is α-synuclein (α-syn). Human genetic studies have shown that mutations (A53T, A30
Publikováno v:
Annals of the New York Academy of Sciences. 760:279-295
Autor:
Robin L. Davis, David T. Denhardt, Kewa Mou, Cecilia A. Lopez, Joe C. Adams, Elizabeth S. Olson
Publikováno v:
Hearing Research. 85:210-222
Localization of protein epitopes and mRNA expression showed that there was a wide-spread distribution of osteopontin (OPN) within the membranous labyrinth of the adult mammalian cochleae. Immunoreaction product and mRNA were found within the stria va
Publikováno v:
Annals of the New York Academy of Sciences. 760:324-326