Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Kevork Khadarian"'
Autor:
Richard L. Lubman, Ching-Fei Chang, Layla Shojaie, Ling Shao, Julian H. McLain, Brett Lindgren, Kevork Khadarian
Publikováno v:
ACG Case Reports Journal
A 35-year-old woman presented to the hospital with a 4-week history of large-volume chylous ascites refractory to paracentesis and new-onset dyspnea. Thoracic computed tomography revealed diffuse pulmonary cystic lesions with pleural effusions, and a
Publikováno v:
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 18(4)
Autor:
Sarah M. Dry, Greg LaChaud, Swati Shrestha, Aaron W. James, Xinli Zhang, Jia Shen, Chia Soo, Kevork Khadarian, Kang Ting
Publikováno v:
Biochemical and Biophysical Research Communications. 460:368-374
NELL-1 (NEL-like Protein 1) is an osteoinductive protein with increasing usage as a bone graft substitute in preclinical animal models. NELL-1 was first identified to have bone-forming properties by its overexpression in fusing cranial sutures. Since
Autor:
Mark Ajalat, Chia Soo, Xinli Zhang, Alan Hwang, Tyler Pritchard, Chirag Chawan, Omar Velasco, Kevork Khadarian, Kambiz Khalilinejad, Greg Asatrian, Jinny Kwak, Aaron W. James, Yulong Zhang, Jia Shen
Publikováno v:
International Journal of Orthopaedics. 2:468-475
NELL-1 induces Sca-1+ mesenchymal progenitor cell expansion in models of bone maintenance and repair
Autor:
Chia Soo, Carolyn A. Meyers, Jin H. Kwak, Aaron W. James, Alan Nguyen, Greg Asatrian, Jia Shen, Kevork Khadarian, Xinli Zhang, Rebecca Tsuei, Cymbeline T. Culiat, Min Lee, Weiming Li, Hsin Chuan Pan, Kang Ting
Publikováno v:
JCI Insight. 2
NELL-1 is a secreted, osteogenic protein first discovered to control ossification of the cranial skeleton. Recently, NELL-1 has been implicated in bone maintenance. However, the cellular determinants of NELL-1's bone-forming effects are still unknown
Autor:
Kevork Khadarian, Shen Pang, Greg Asatrian, Jia Shen, Jung Kim, Raghav Goyal, Omar Velasco, Xinli Zhang, Chia Soo, Greg Chung, Kang Ting, Aaron W. James
Publikováno v:
Tissue Engineering Part A. 20:2699-2710
Introduction: Skeletal aging is associated not only with alterations in osteoblast (OB) and osteoclast (OC) number and activity within the basic metabolic unit, but also with increased marrow adiposity. Peroxisome proliferator-activated receptor gamm
Autor:
Kevork Khadarian, Greg Asatrian, James B. Zhang, Aaron W. James, Kang Ting, Jia Shen, Stephanie Ho, Chia Soo, Janette N. Zara, Hyun Ju Kim
Publikováno v:
Tissue Engineering Part A. 19:2390-2401
Bone-morphogenetic protein 2 (BMP2) is currently the only Food and Drug Administration-approved osteoinductive growth factor used in clinical settings for bone regeneration and repair. However, the use of BMP2 is encumbered by numerous clinical compl
Autor:
Janette N. Zara, Kevin S. Lee, Chia Soo, Kevork Khadarian, Sotirios Tetradis, Aaron W. James, Ronald K. Siu, Kang Ting, Jia Shen, Michael F. Chiang, Alan Nguyen, Shen Pang, Min Lee, Xinli Zhang, Greg Asatrian
Publikováno v:
The American journal of pathology. 186(2)
The differentiation factor NEL-like molecule-1 (NELL-1) has been reported as osteoinductive in multiple in vivo preclinical models. Bone morphogenetic protein (BMP)-2 is used clinically for skeletal repair, but in vivo administration can induce abnor
Autor:
Minwei Zhu, Jia Shen, Jiahang Sun, Zhenfeng Jiang, Hong Shen, Yongri Zheng, Guangzhi Wang, Mian Guo, Kelvin Xi Zhang, Yan Zhao, Shan Yu, Kevork Khadarian, Chuncheng Xie, Xiaoming Zhang, Zhiguo Lin, Chuanlu Jiang
Publikováno v:
Cancer letters. 360(1)
Gliomas are the most common and deadly type of brain tumor. In spite of progressive treatments, patient prognosis has not improved significantly. MicroRNAs are considered promising candidates for glioma therapy. MiR-603 was found overexpressed in bot
Autor:
Albert Duy Ha, Jia Shen, Xiaoming Zhang, Zhiguo Lin, Kevork Khadarian, Wenzhong Du, Li Hu, Zhichao Wu, Mian Guo, Dunyue Lu, Zhenfeng Jiang, Jiahang Sun
Publikováno v:
Carcinogenesis. 35(8)
Bone morphogenetic protein-2 (BMP-2), a member of the transforming growth factor-β family, plays critical roles in cell differentiation, modeling and regeneration processes in several tissues. BMP-2 is also closely associated with various malignant