Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Kevinkumar Kansagra"'
Autor:
Anuja Pandit, Nirav Bhalani, B.L. Shashi Bhushan, Parshottam Koradia, Shweta Gargiya, Vinay Bhomia, Kevinkumar Kansagra
Publikováno v:
International Journal of Infectious Diseases, Vol 105, Iss , Pp 516-521 (2021)
Objective: To evaluate the efficacy and safety of pegylated interferon alfa-2b (PEG IFN-α2b) along with the standard of care (SOC) in subjects with moderate COVID-19. Methods: In this phase 2, randomized, open-label study, adult subjects aged ≥18
Externí odkaz:
https://doaj.org/article/db1045fd9fbc4939a9d4129a5d9bf40c
Autor:
Anuja Pandit, Nirav Bhalani, B.L. Shashi Bhushan, Parshottam Koradia, Shweta Gargiya, Vinay Bhomia, Kevinkumar Kansagra
Publikováno v:
International Journal of Infectious Diseases, Vol 109, Iss , Pp 322- (2021)
Externí odkaz:
https://doaj.org/article/a241828a658d44b9a2af2cd2625831a8
Autor:
Taufik Momin, Kevinkumar Kansagra, Hardik Patel, Sunil Sharma, Bhumika Sharma, Jatin Patel, Ravindra Mittal, Jayesh Sanmukhani, Kapil Maithal, Ayan Dey, Harish Chandra, Chozhavel TM Rajanathan, Hari PR Pericherla, Pawan Kumar, Anjali Narkhede, Deven Parmar
Publikováno v:
EClinicalMedicine, Vol 38, Iss , Pp 101020- (2021)
Background: ZyCoV-D is a DNA vaccine candidate, which comprises a plasmid DNA carrying spike-S gene of SARS-CoV-2 virus along with gene coding for signal peptide. The spike(S) region includes the receptor-binding domain (RBD), which binds to the huma
Externí odkaz:
https://doaj.org/article/a45a671cdc6948cab37598bd0f28efc4
Autor:
Bridget E Barber, Melissa Fernandez, Hardik Babubhai Patel, Catalina Barcelo, Stephen D Woolley, Harilal Patel, Stacey Llewellyn, Azrin N Abd-Rahman, Sunil Sharma, Mukul Jain, Ashok Ghoghari, Ilaria Di Resta, Aline Fuchs, Ioanna Deni, Tomas Yeo, Sachel Mok, David A Fidock, Stephan Chalon, Jörg J Möhrle, Deven Parmar, James S McCarthy, Kevinkumar Kansagra
Publikováno v:
The Lancet Infectious Diseases. 22:879-890
Background\ud \ud New antimalarials with novel mechanisms of action are needed to combat the emergence of drug resistance. Triaminopyrimidines comprise a novel antimalarial class identified in a high-throughput screen against asexual blood-stage Plas
Autor:
Akash, Khobragade, Suresh, Bhate, Vijendra, Ramaiah, Shrikant, Deshpande, Krishna, Giri, Himanshu, Phophle, Pravin, Supe, Inderjeet, Godara, Ramesh, Revanna, Rajnish, Nagarkar, Jayesh, Sanmukhani, Ayan, Dey, T M Chozhavel, Rajanathan, Kevinkumar, Kansagra, Parshottam, Koradia
Publikováno v:
The Lancet. 399:1313-1321
ZyCoV-D, a DNA-based vaccine, showed promising safety and immunogenicity in a phase 1/2 trial. We now report the interim efficacy results of phase 3 clinical trial with ZyCoV-D vaccine in India.We conducted an interim analysis of a multicentre, doubl
Autor:
Hardik Patel, Taufik Momin, Kevinkumar Kansagra, Harilal Patel, Chintan Shah, Ajaykumar Barot, Jay Bhavsar, Kuldipsinh Zala, Deven Parmar
Publikováno v:
Clinical pharmacology in drug developmentReferences.
This randomized, single-treatment, 2-sequence study evaluated the food effect on oral bioavailability of desidustat. Healthy adult male and female subjects were enrolled and randomly assigned to receive desidustat 50 mg orally in a fasting state in o
Autor:
Georges F R Radohery, Jeremy Gower, Bridget E Barber, Kevinkumar Kansagra, Jörg J Möhrle, Miles P Davenport, James S McCarthy, David S Khoury, Maria Rebelo
Publikováno v:
The Lancet. Infectious diseases. 22(6)
Autor:
Sishir, Gang, Prakash, Khetan, Deepak, Varade, Venkata Ramakrishna, Chinta, Siddharth, Mavani, Umesh, Gupta, S Venkata Krishna, Reddy, Sunil, Rajanna, Tarun, Jeloka, Vivek, Ruhela, Kevinkumar, Kansagra, Pooja, Kanani, Jayesh, Bhatt, Kuldipsinh, Zala
Publikováno v:
American journal of nephrology. 53(5)
A phase 3 study to assess the efficacy and safety of the desidustat, an oral hypoxia-inducible factor prolyl hydroxylase inhibitor, against the epoetin alfa for the treatment of anemia in patients with chronic kidney disease (CKD) with dialysis depen
Autor:
Deven Parmar, Sanjeev Kumar Mendiratta, RajendraKumar Verma, Anurag Parihar, Abhishek Gupta, Renuka Munshi, HiraLal Bhalla, Jatin Patel, Ruchir Shah, Prakash Kurmi, Dinesh C. Agarwal, Nitin Sharma, Shuchi Joshi, Shrikant Sharma, Swapnil Bhoge, Avinash Gawande, Pankaj Kalita, Gaurav Chhaya, Kevinkumar Kansagra, Harish Bekkalele, Harilal Patel
Publikováno v:
Clinical Infectious Diseases. 73:e2722-e2728
BackgroundLimited supply, cost and potential for severe adverse effects observed with the blood derived rabies immunoglobulin products has led to search for alternative therapies. This issue has been addressed by developing an anti-rabies monoclonal
Autor:
Dhananjai, Agrawal, Deepak, Varade, Hardik, Shah, Alm, Nazar, Jayakumar, Krishnan, Vineet, Shukla, Chinta, Ramakrishna, Mahel Chinthana, Bandara Galahitiyawa, Sidhharth B, Mavani, Sunil, Rajanna, Petkar, Jikki, Shamila, De Silva, Vivek, Ruhela, Parshottam, Koradia, Kevinkumar, Kansagra, Pooja, Kanani, Nitin, Sharma, Kuldipsinh, Zala, Deven, Parmar
Publikováno v:
American journal of nephrology. 53(5)
Desidustat, an oral hypoxia-inducible factor prolyl hydroxylase inhibitor, is being developed to treat anemia in patients with chronic kidney disease (CKD) without dialysis dependency.In total, 588 patients with a clinical diagnosis of anemia due to