Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Kevin Yao"'
Publikováno v:
Cancer Medicine, Vol 12, Iss 5, Pp 5590-5602 (2023)
Abstract Background Immune checkpoint proteins play critical functions during the immune response to cancer and have been targeted by immune checkpoint blockade therapy. V‐domain Ig suppressor of T cell activation (VSIR) is one of these immune chec
Externí odkaz:
https://doaj.org/article/74d457760b224b3c9bc02d39280ff9f7
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract To improve cancer precision medicine, prognostic and predictive biomarkers are critically needed to aid physicians in deciding treatment strategies in a personalized fashion. Due to the heterogeneous nature of cancer, most biomarkers are exp
Externí odkaz:
https://doaj.org/article/10cf8326c1a94e2a8b50470ddc5e9639
Publikováno v:
Cancer Medicine, Vol 11, Iss 4, Pp 1232-1243 (2022)
Abstract Background B‐Raf V600E mutations account for about half of all skin cutaneous melanoma cases, and patients with this mutation are sensitive to BRAF inhibitors. However, aberrations in other genes in the MAPK/ERK pathway may cascade a simil
Externí odkaz:
https://doaj.org/article/11f04b05a5984b4f9ec40cd7835b8049
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-16 (2022)
Abstract Chromatin accessibility is essential for transcriptional activation of genomic regions. It is well established that transcription factors (TFs) and histone modifications (HMs) play critical roles in chromatin accessibility regulation. Howeve
Externí odkaz:
https://doaj.org/article/71beec6330d24f74bced0c7a522b5bdb
Publikováno v:
Translational Oncology, Vol 17, Iss , Pp 101327- (2022)
Compared to Caucasians (CAs), African Americans (AAs) have a higher rate of incidence and mortality in prostate cancer and are prone to be diagnosed at later stages. To understand this racial disparity, molecular features of different types, includin
Externí odkaz:
https://doaj.org/article/6b299c2930b7409db395a2e5db679648
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 3, p e1009495 (2022)
Although estrogen-receptor-positive (ER+) breast cancer is generally associated with favorable prognosis, clinical outcome varies substantially among patients. Genomic assays have been developed and applied to predict patient prognosis for personaliz
Externí odkaz:
https://doaj.org/article/b94f92f0ea4d4b6a83a1d9b205797ec5
Publikováno v:
Clinical and Translational Discovery, Vol 2, Iss 1, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/3c5f35bf3a584fe79898c1aa97a205c7
Table S1. Colon adenocarcinoma and rectum adenocarcinoma microarray datasets used for prognosis analysis in this study. For each dataset, its GEO ID, platform, author, PMID, survival information type, number of samples, number of MSS-A and MSS-N, age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199137e0062fb8037a12bcf3e8b79fb2
https://doi.org/10.1158/0008-5472.22430602
https://doi.org/10.1158/0008-5472.22430602
Supplementary Material. Legends for supplementary tables and figures are included
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b08b87391c04f3ab07cc4a1d7f8f2de
https://doi.org/10.1158/0008-5472.22430605.v1
https://doi.org/10.1158/0008-5472.22430605.v1
Colorectal cancer is the third leading cause of cancer-related death in the United States. About 15% of colorectal cancers are associated with microsatellite instability (MSI) due to loss of function in the DNA mismatch repair pathway. This subgroup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2543774156b5d3ef731ddfd1b7a68f71
https://doi.org/10.1158/0008-5472.c.6513655
https://doi.org/10.1158/0008-5472.c.6513655