Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kevin Y. Cao"'
Autor:
Kevin Y. Cao, Katsuya Nagaoka, Grace Hildebrand, Chiung-Kuei Huang, Joud Mulla, Shaolei Lu, Zhixiang Cheng, Amalia Bay, William Mueller, Dan Liu
Publikováno v:
Liver Research, Vol 4, Iss 2, Pp 94-100 (2020)
Background Non-alcoholic liver disease is of increased concern and contributing to economic burdens not only in developing countries but in developed countries as well. Identifying the biomarker of early diagnosis and early intervention approaches fo
Autor:
Grace Hildebrand, William Mueller, Dan Liu, Bei Sun, Joselynn Wallace, Jialin Meng, Chiung‐Kueihiung‐Kuei Huang, Hongyu Zhang, Shaolei Lu, Kevin Y. Cao, Yamei Zhou, Katsuya Nagaoka, Amalia Bay, Joud Mulla, Zhixiang Cheng, Xuewei Bai, Xiang-Hui Dong, Chengcheng Ji, Jack R. Wands
Publikováno v:
Hepatology
BACKGROUND AND AIMS Cholangiocarcinoma (CCA) is a highly lethal disease without effective therapeutic approaches. The whole-genome sequencing data indicate that about 20% of patients with CCA have isocitrate dehydrogenase 1 (IDH1) mutations, which ha
Autor:
Chengcheng Ji, Miran Kim, Kevin Y. Cao, Hongyu Zhang, Yoshifumi Iwagami, Jing Zou, Chiung-Kuei Huang
Publikováno v:
Journal of Cellular and Molecular Medicine
MicroRNAs (miRs) have been recently shown to be heavily involved in the development of alcoholic liver disease (ALD) and suggested as a potential therapeutic target in ALD. The miR‐34a was consistently reported to be significantly elevated in sever
Autor:
Katsuya Nagaoka, Chengcheng Ji, Yoshifumi Iwagami, Jack R. Wands, Jonathan Lawrence, Jing Zou, Hongyu Zhang, Sarah Casulli, Keri Brooks, Kevin Y. Cao, Rolf Carlson, William Mueller, Shaolei Lu, Chiung-Kuei Huang
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33(2)
The 5-hydroxymethylcytosine (5hmc) is a newly identified epigenetic modification thought to be regulated by the TET family of proteins. Little information is available about how ethanol consumption may modulate 5hmC formation and alcoholic liver dise
Aspartate beta-hydroxylase promotes cholangiocarcinoma progression by modulating RB1 phosphorylation
Autor:
Kousuke Ogawa, Chiung-Kuei Huang, Yoshifumi Iwagami, Shaolei Lu, Kevin Y. Cao, Sarah Casulli, Jing Zou, Chengcheng Ji, Jack R. Wands, Rolf I. Carlson, Jin-Song Gao, Katsuya Nagaoka
Publikováno v:
Cancer letters. 429
Cholangiocarcinoma (CCA) is a highly lethal and aggressive disease. Recently, IDH1/2 mutations have been identified in approximately 20% of CCAs which suggests an involvement of 2-oxoglutarate (2-OG) -dependent dioxygenases in oncogenesis. We investi