Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Kevin Willemart"'
Autor:
Thibault Barbier, Arnaud Machelart, Amaia Zúñiga-Ripa, Hubert Plovier, Charlotte Hougardy, Elodie Lobet, Kevin Willemart, Eric Muraille, Xavier De Bolle, Emile Van Schaftingen, Ignacio Moriyón, Jean-Jacques Letesson
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Erythritol is the preferential carbon source for most brucellae, a group of facultative intracellular bacteria that cause a worldwide zoonosis. Since this polyol is abundant in genital organs of ruminants and swine, it is widely accepted that erythri
Externí odkaz:
https://doaj.org/article/575807365bd94234a9acf1ac1f3de78e
Autor:
Jean-Pierre Gorvel, Stanimir Kambarev, Suzana P. Salcedo, Kevin Willemart, Frédérique Lembo, Jean-Paul Borg, Magali Bonici, Francine C A Gérard, Jean-Baptiste Luizet, Jean Celli, Julie Raymond, Thais Lourdes Santos Lacerda, Emeline Barbieux, Eric Muraille
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (32), pp.e2105324118. ⟨10.1073/pnas.2105324118⟩
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (32), pp.e2105324118. ⟨10.1073/pnas.2105324118⟩
International audience; Perturbation of the endoplasmic reticulum (ER), a central organelle of the cell, can have critical consequences for cellular homeostasis. An elaborate surveillance system known as ER quality control ensures that cells can resp
Autor:
Charles Nicaise, Kevin Willemart, Florian Poulain, Nicolas Gillet, Noémie Avalosse, Riselane Lotfi, Jacques Gilloteaux, Noelle Ninanne, Noémie Lejeune, Kathleen De Swert, Valery Bielarz
Publikováno v:
Brain Research
Bielarz, V, WILLEMART, KEVIN, Avalosse, N, De Swert, K, Lotfi, R, Lejeune, N, Poulain, F, Ninanne, N, GILLOTEAUX, J, GILLET, NICOLAS & Nicaise, C 2021, ' Susceptibility of neuroblastoma and glioblastoma cell lines to SARS-CoV-2 infection ', Brain research, vol. 1758, 147344 . https://doi.org/10.1016/j.brainres.2021.147344
Bielarz, V, WILLEMART, KEVIN, Avalosse, N, De Swert, K, Lotfi, R, Lejeune, N, Poulain, F, Ninanne, N, GILLOTEAUX, J, GILLET, NICOLAS & Nicaise, C 2021, ' Susceptibility of neuroblastoma and glioblastoma cell lines to SARS-CoV-2 infection ', Brain research, vol. 1758, 147344 . https://doi.org/10.1016/j.brainres.2021.147344
Modelling cell infection in-a-dish can represent a useful tool to understand the susceptibility of different cell types towards severe acute respiratory coronavirus-2 (SARS-CoV-2) and to decipher its neurotropism. In this perspective, retinoic acid (
Publikováno v:
J Virol
Human adenoviruses (HAdVs) are a large family of DNA viruses that include more than 100 genotypes divided into seven species (A to G) and induce respiratory tract infections, gastroenteritis, and conjunctivitis. Genetically modified adenoviruses are
Autor:
Ignacio Moriyón, Amaia Zúñiga-Ripa, Thibault Godard, Hubert Plovier, Xavier De Bolle, Thibault Barbier, Kevin Willemart, Emile Van Schaftingen, Jean-Jacques Letesson, Arnaud Machelart, Christoph Wittmann
Publikováno v:
Machelart, A, Willemart, K, Zúñiga-Ripa, A, Godard, T, Plovier, H, Wittmann, C, Moriyón, I, De Bolle, X, Van Schaftingen, E, Letesson, J-J & Barbier, T 2020, ' Convergent evolution of zoonotic Brucella species toward the selective use of the pentose phosphate pathway ', Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 42, pp. 26374-26381 . https://doi.org/10.1073/pnas.2008939117
Mechanistic understanding of the factors that govern host tropism remains incompletely understood for most pathogens. Brucella species, which are capable of infecting a wide range of hosts, offer a useful avenue to address this question. We hypothesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d4d0123a63e1eff20756f8437ccd5a5
https://pure.unamur.be/ws/files/52044708/Machelart_et_al_2020.pdf
https://pure.unamur.be/ws/files/52044708/Machelart_et_al_2020.pdf
Autor:
Arnaud, Machelart, Kevin, Willemart, Amaia, Zúñiga-Ripa, Thibault, Godard, Hubert, Plovier, Christoph, Wittmann, Ignacio, Moriyón, Xavier, De Bolle, Emile, Van Schaftingen, Jean-Jacques, Letesson, Thibault, Barbier
Publikováno v:
Proc Natl Acad Sci U S A
Mechanistic understanding of the factors that govern host tropism remains incompletely understood for most pathogens. Brucella species, which are capable of infecting a wide range of hosts, offer a useful avenue to address this question. We hypothesi
Autor:
Benoît Muylkens, Emmanuel André, Gabrielle Trozzi, Noémie Lejeune, Lize Cuypers, Nicolas Burton, Pierre Bogaerts, Suzanne Loret, Marc Van Ranst, Srdan Pejakovic, Damien Coupeau, Laura Bonil, Florian Poulain, Kevin Willemart, Astrid Petit, Laetitia Wiggers, Lies Laenen, Nicolas Gillet
Publikováno v:
Methods and Protocols, Vol 3, Iss 59, p 59 (2020)
Methods and Protocols
Methods and protocols, Vol. 3, no. 3, p. E59 (2020)
Volume 3
Issue 3
Methods and Protocols
Methods and protocols, Vol. 3, no. 3, p. E59 (2020)
Volume 3
Issue 3
The emergence of the SARS-CoV-2 virus and the exponential growth of COVID-19 cases have created a major crisis for public health systems. The critical identification of contagious asymptomatic carriers requires the isolation of viral nucleic acids, r
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 8, p e1008718 (2020)
PLoS Pathogens, Vol 16, Iss 8, p e1008718 (2020)
APOBEC3 enzymes are innate immune effectors that introduce mutations into viral genomes. These enzymes are cytidine deaminases which transform cytosine into uracil. They preferentially mutate cytidine preceded by thymidine making the 5’TC motif the
Autor:
Xavier De Bolle, Arnaud Machelart, Katy Poncin, Eric Muraille, Emanuele G. Biondi, Nayla Francis, Agnès Roba, Kevin Willemart, Nicolas Zeippen, Georges Potemberg, Antonella Fioravanti, Stéphane P. Vincent, Ravikumar Jimmidi
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), ⟨10.1038/s41467-019-12516-8⟩
Nature Communications, 2019, 10 (1), ⟨10.1038/s41467-019-12516-8⟩
Poncin, K, Roba, A, Jimmidi, R, Potemberg, G, Fioravanti, A, Francis, N, Willemart, K, Zeippen, N, Machelart, A, Biondi, E G, Muraille, E, Vincent, S P & De Bolle, X 2019, ' Occurrence and repair of alkylating stress in the intracellular pathogen Brucella abortus ', Nature Communications, vol. 10, no. 1, 4847, pp. 4847 . https://doi.org/10.1038/s41467-019-12516-8
Nature communications, 10 (1
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications, Nature Publishing Group, 2019, 10 (1), ⟨10.1038/s41467-019-12516-8⟩
Nature Communications, 2019, 10 (1), ⟨10.1038/s41467-019-12516-8⟩
Poncin, K, Roba, A, Jimmidi, R, Potemberg, G, Fioravanti, A, Francis, N, Willemart, K, Zeippen, N, Machelart, A, Biondi, E G, Muraille, E, Vincent, S P & De Bolle, X 2019, ' Occurrence and repair of alkylating stress in the intracellular pathogen Brucella abortus ', Nature Communications, vol. 10, no. 1, 4847, pp. 4847 . https://doi.org/10.1038/s41467-019-12516-8
Nature communications, 10 (1
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
It is assumed that intracellular pathogenic bacteria have to cope with DNA alkylating stress within host cells. Here we use single-cell reporter systems to show that the pathogen Brucella abortus does encounter alkylating stress during the first hour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb1d24f7e59a59df9acf427e3b9dd9bd
https://biblio.vub.ac.be/vubir/occurrence-and-repair-of-alkylating-stress-in-the-intracellular-pathogen-brucella-abortus(32eb28a2-69fe-4808-870b-f7c0710f221e).html
https://biblio.vub.ac.be/vubir/occurrence-and-repair-of-alkylating-stress-in-the-intracellular-pathogen-brucella-abortus(32eb28a2-69fe-4808-870b-f7c0710f221e).html
Autor:
Katy Poncin, Jean-Jacques Letesson, Nayla Francis, Victoria Vassen, Kevin Willemart, Emanuele G. Biondi, Thi Anh Phuong Ong, Luca Rappez, Xavier De Bolle, Antonella Fioravanti
Publikováno v:
Molecular Microbiology. 103:780-797
Brucella abortus is a pathogen infecting cattle, able to survive, traffic, and proliferate inside host cells. It belongs to the Alphaproteobacteria, a phylogenetic group comprising bacteria with free living, symbiotic, and pathogenic lifestyles. An e