Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Kevin Welsher"'
Autor:
Wei-You Li, Shuhui Yin, Szu-Wei Huang, Ming-Hui Yang, Patricia MT. Chen, Shang-Rung Wu, Kevin Welsher, Haw Yang, Yi-Ming Arthur Chen
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 56, Iss 2, Pp 257-266 (2023)
Background: The exploration of virology knowledge was limited by the optical technology for the observation of virus. Previously, a three-dimensional multi-resolution real-time microscope system (3D-MRM) was developed to observe the uptake of HIV-1-t
Externí odkaz:
https://doaj.org/article/eb2d4cf9f066454f94f51d520f2fdc6a
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Single molecule observation has been limited to tethered molecules to ensure that the target remains in the field of view (FOV). Here, the authors develop a real-time tracking method that locks onto rapidly diffusing targets and tracks them in a 3D v
Externí odkaz:
https://doaj.org/article/e5b9c20cbff141eab604d5fdecdb9b17
Autor:
Siddharth Patel, N. Ashwanikumar, Ema Robinson, Yan Xia, Cosmin Mihai, Joseph P. Griffith, Shangguo Hou, Adam A. Esposito, Tatiana Ketova, Kevin Welsher, John L. Joyal, Örn Almarsson, Gaurav Sahay
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Endosomal sequestration of lipid-based nanoparticles is a barrier to delivery of nucleic acids. Here the authors test an array of cholesterol variants and perform in-depth investigation of nanoparticle shape, internal structure and intracellular traf
Externí odkaz:
https://doaj.org/article/9657095ce49a4c28856fa65a8bc45d65
Autor:
Chen Zhang, Kevin Welsher
Publikováno v:
Entropy, Vol 23, Iss 5, p 498 (2021)
In this work, we present a 3D single-particle tracking system that can apply tailored sampling patterns to selectively extract photons that yield the most information for particle localization. We demonstrate that off-center sampling at locations pre
Externí odkaz:
https://doaj.org/article/335da72d2ff54703bf7e8fe12d975f1c
Autor:
Siddharth Patel, N. Ashwanikumar, Ema Robinson, Yan Xia, Cosmin Mihai, Joseph P. Griffith, Shangguo Hou, Adam A. Esposito, Tatiana Ketova, Kevin Welsher, John L. Joyal, Örn Almarsson, Gaurav Sahay
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/128cc779536244378fda8c2ba44fd836
Publikováno v:
Molecules, Vol 24, Iss 15, p 2826 (2019)
Single molecule fluorescence spectroscopy has been largely implemented using methods which require tethering of molecules to a substrate in order to make high temporal resolution measurements. However, the act of tethering a molecule requires that th
Externí odkaz:
https://doaj.org/article/7192a2cf81c9435a841d400360bc75a4
Autor:
Xiaochen Tan, Kevin Welsher
Publikováno v:
Angew Chem Int Ed Engl
Nanoparticles (NPs) adsorb proteins when exposed to biological fluids, forming a dynamic protein corona that affects their fate in biological environments. A comprehensive understanding of the protein corona is lacking due to the inability of current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04497f80bd261000c4c655a4d48d9a72
https://doi.org/10.1002/ange.202105741
https://doi.org/10.1002/ange.202105741
Autor:
Kevin Welsher, Anastasia Niver
Despite successes in tracking single molecules in vitro, the extension of active-feedback single-particle methods to tracking rapidly diffusing and unconfined proteins in live cells has not been realized. Since existing active-feedback localization m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b205c059c35df386e4b3fa25e7485f97
https://doi.org/10.1101/2022.08.05.502973
https://doi.org/10.1101/2022.08.05.502973
3D single-particle tracking has the potential to resolve the molecular level forces which dictate particle motion in biological systems. However, the information gleaned from 3D single-particle tracking often cannot resolve underlying nanoscale poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd7e6b24c2f7329831b24a317fef5aff
https://doi.org/10.1101/2022.06.27.497788
https://doi.org/10.1101/2022.06.27.497788
Publikováno v:
Multiscale Imaging and Spectroscopy III.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c97b33b710efd5105826bfd49324f76
https://doi.org/10.1117/12.2607151
https://doi.org/10.1117/12.2607151