Výsledky vyhledávání - "Kevin W. Waddell"

15N Hyperpolarization by Reversible Exchange Using SABRE-SHEATH

Autor: Aaron M. Coffey, Fan Shi, Eduard Y. Chekmenev, Warren S. Warren, Kevin W. Waddell, Milton L. Truong, Thomas Theis, Roman V. Shchepin, Boyd M. Goodson

Publikováno v: The Journal of Physical Chemistry. C, Nanomaterials and Interfaces

NMR signal amplification by reversible exchange (SABRE) is a NMR hyperpolarization technique that enables nuclear spin polarization enhancement of molecules via concurrent chemical exchange of a target substrate and parahydrogen (the source of spin o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::182b1bbbf2aff634bbf02e2457b05709
https://doi.org/10.1021/acs.jpcc.5b01799

Zobrazit plný text záznamu

Nanoscale Catalysts for NMR Signal Enhancement by Reversible Exchange

Autor: Aaron M. Coffey, Eduard Y. Chekmenev, Fan Shi, Kevin W. Waddell, Boyd M. Goodson

Publikováno v: The Journal of Physical Chemistry. C, Nanomaterials and Interfaces

Two types of nanoscale catalysts were created to explore NMR signal enhancement via reversible exchange (SABRE) at the interface between heterogeneous and homogeneous conditions. Nanoparticle and polymer comb variants were synthesized by covalently t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b8069d120025ab29c8390d8b7e35fa8
http://europepmc.org/articles/PMC4501382

Zobrazit plný text záznamu

Microtesla SABRE Enables 10% Nitrogen-15 Nuclear Spin Polarization

Autor: Eduard Y. Chekmenev, Fan Shi, Thomas Theis, Kevin W. Waddell, Milton L. Truong, Warren S. Warren, Aaron M. Coffey, Roman V. Shchepin, Boyd M. Goodson

Publikováno v: Journal of the American Chemical Society

Parahydrogen is demonstrated to efficiently transfer its nuclear spin hyperpolarization to nitrogen-15 in pyridine and nicotinamide (vitamin B(3) amide) by conducting "signal amplification by reversible exchange" (SABRE) at microtesla fields within a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dda151a37d221d413032f647dac2a323
http://europepmc.org/articles/PMC4333583

Zobrazit plný text záznamu

In Situ and Ex Situ Low-Field NMR Spectroscopy and MRI Endowed by SABRE Hyperpolarization

Autor: Kevin W. Waddell, Eduard Y. Chekmenev, Roman V. Shchepin, Kirill V. Kovtunov, Milton L. Truong, Danila A. Barskiy, Boyd M. Goodson, Kirsten A. Groome, Aaron M. Coffey, Ping He, Fan Shi, Quinn A. Best, Igor V. Koptyug

Publikováno v: ChemPhysChem. 15:4100-4107

By using 5.75 and 47.5 mT nuclear magnetic resonance (NMR) spectroscopy, up to 10(5)-fold sensitivity enhancement through signal amplification by reversible exchange (SABRE) was enabled, and subsecond temporal resolution was used to monitor an exchan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d8d8483c1f578e061a6aa4efd04057
https://doi.org/10.1002/cphc.201402607

Zobrazit plný text záznamu

High-Resolution Low-Field Molecular Magnetic Resonance Imaging of Hyperpolarized Liquids

Autor: Danila A. Barskiy, Igor V. Koptyug, Kevin W. Waddell, Eduard Y. Chekmenev, Boyd M. Goodson, Fan Shi, Kirsten A. Groome, Ping He, Quinn A. Best, Kirill V. Kovtunov, Roman V. Shchepin, Aaron M. Coffey

Publikováno v: Analytical Chemistry

We demonstrate the feasibility of microscale molecular imaging using hyperpolarized proton and carbon-13 MRI contrast media and low-field (47.5 mT) preclinical scale (38 mm i.d.) 2D magnetic resonance imaging (MRI). Hyperpolarized proton images with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56968390979cf3585f0363fae24a3f36
https://doi.org/10.1021/ac501638p

Zobrazit plný text záznamu

Heteronuclear refocusing by nonlinear phase and amplitude modulation on a single transmitter channel

Autor: Kevin W. Waddell, Raul D. Colon, Jay Moore, Sasidhar Tadanki

Publikováno v: Journal of Magnetic Resonance. 245:58-62

The application of low magnetic fields to heteronuclear NMR has expanded recently alongside the emergence of methods for achieving near unity polarization of spin ensembles, independent of magnetic field strength. The parahydrogen induced hyperpolari

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e4fc9fb4082c7fa3872d266286ef8b
https://doi.org/10.1016/j.jmr.2014.05.010

Zobrazit plný text záznamu

Demonstration of Heterogeneous Parahydrogen Induced Polarization Using Hyperpolarized Agent Migration from Dissolved Rh(I) Complex to Gas Phase

Autor: Danila A. Barskiy, Kevin W. Waddell, Igor V. Koptyug, Eduard Y. Chekmenev, Aaron M. Coffey, Roman V. Shchepin, Kirill V. Kovtunov

Publikováno v: Analytical Chemistry

Parahydrogen-induced polarization (PHIP) was used to demonstrate the concept that highly polarized, catalyst-free fluids can be obtained in a catalysis-free regime using a chemical reaction with molecular addition of parahydrogen to a water-soluble R

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d46e5d445c79b1e8c200c1cdf2bb399
http://europepmc.org/articles/PMC4079322

Zobrazit plný text záznamu

Sub-second proton imaging of13C hyperpolarized contrast agents in water

Autor: Kevin W. Waddell, Eduard Y. Chekmenev, Roman V. Shchepin, Milton L. Truong, Aaron M. Coffey

Publikováno v: Contrast Media & Molecular Imaging. 9:333-341

Indirect proton detection of 13C hyperpolarized contrast agents potentially enables greater sensitivity. Presented here is a study of sub-second projection imaging of hyperpolarized 13C contrast agent addressing the obstacle posed by water suppressio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::55a9e1609d76a037df60049728d3171a
https://doi.org/10.1002/cmmi.1579

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání