Zobrazeno 1 - 10 of 25 pro vyhledávání: '"Kevin W. Morin"'
1
Akademický článek
Optimized Clinical Strategies for Treatment-Resistant Depression: Integrating Ketamine Protocols with Trauma- and Attachment-Informed Psychotherapy
Autor: Sherry-Anne Muscat, Glenn Hartelius, Courtenay Richards Crouch, Kevin W. Morin
Publikováno v: Psych, Vol 4, Iss 1, Pp 119-141 (2022)
Strategically timed trauma- and attachment-informed psychotherapy to address underlying emotional wounds, paired with ketamine administered in precision-calibrated doses to ensure high-entropy brain states, may be key to improving the quality and dur
Externí odkaz: https://doaj.org/article/35431b99743c42219adcb07d84e31b82
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2
Akademický článek
An Integrative Approach to Ketamine Therapy May Enhance Multiple Dimensions of Efficacy: Improving Therapeutic Outcomes With Treatment Resistant Depression
Autor: Sherry-Anne Muscat, Glenn Hartelius, Courtenay Richards Crouch, Kevin W. Morin
Publikováno v: Frontiers in Psychiatry, Vol 12 (2021)
Research over the last two decades has established ketamine as a safe, effective, fast-acting, and sustained antidepressant that significantly reduces adverse symptoms associated with depression, even in patients who are treatment resistant. Much of
Externí odkaz: https://doaj.org/article/a499c78a4b10447d8cf867dd4fa082f1
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3
Akademický článek
Ketamine-Assisted and Culturally Attuned Trauma Informed Psychotherapy as Adjunct to Traditional Indigenous Healing: Effecting Cultural Collaboration in Canadian Mental Health Care
Autor: Sherry-Anne Muscat, Geralyn Dorothy Wright, Kristy Bergeron, Kevin W. Morin, Courtenay Richards Crouch, Glenn Hartelius
Publikováno v: Behavioral Sciences, Vol 11, Iss 9, p 118 (2021)
Ketamine therapy with culturally attuned trauma-informed psychotherapy in a collaborative cross-cultural partnership may provide a critical step in the operationalization and optimization of treatment effectiveness in diverse populations and may prov
Externí odkaz: https://doaj.org/article/4ba0f19d24c7487799eb3c45a9688657
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4
An Integrative Approach to Ketamine Therapy May Enhance Multiple Dimensions of Efficacy: Improving Therapeutic Outcomes With Treatment Resistant Depression
Autor: Courtenay Richards Crouch, Sherry-Anne Muscat, Glenn Hartelius, Kevin W. Morin
Publikováno v: Frontiers in Psychiatry, Vol 12 (2021)
Frontiers in Psychiatry
Research over the last two decades has established ketamine as a safe, effective, fast-acting, and sustained antidepressant that significantly reduces adverse symptoms associated with depression, even in patients who are treatment resistant. Much of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b5d3db2a8aca210fadd99eebb0b8adf
https://doi.org/10.3389/fpsyt.2021.710338
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5
Retrospective Observational Study of Daytime Add-On Administration of Zopiclone to Difficult-to-Treat Psychiatric Inpatients With Unpredictable Aggressive Behavior, With or Without EEG Dysrhythmia
Autor: Manhaz Salsali, Maryam Alikouzehgaran, Ubaid Abdullah, Wanda Westwood, Alfonso Ceccherini-Nelli, Zahid Latif, Lisa Burback, Kevin W. Morin, Karthikeyan Ganapathy, Elena Bucuci, Patrick J. White, Janice Orris, Daniel Li
Publikováno v: Frontiers in Psychiatry
Frontiers in Psychiatry, Vol 12 (2021)
Managing violent behavior is a particularly challenging aspect of hospital psychiatric care. Available pharmacological interventions are often unsatisfactory.Aim: To assess the effectiveness and safety of daytime zopiclone add-on administration in vi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52853e3b7a9b5268a8f1253ef4927af6
http://europepmc.org/articles/PMC8415882
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6
Ketamine-Assisted and Culturally Attuned Trauma Informed Psychotherapy as Adjunct to Traditional Indigenous Healing: Effecting Cultural Collaboration in Canadian Mental Health Care
Autor: Glenn Hartelius, Geralyn Dorothy Wright, Kevin W. Morin, Sherry-Anne Muscat, Kristy Bergeron, Courtenay Richards Crouch
Publikováno v: Behavioral Sciences
Behavioral Sciences, Vol 11, Iss 118, p 118 (2021)
Ketamine therapy with culturally attuned trauma-informed psychotherapy in a collaborative cross-cultural partnership may provide a critical step in the operationalization and optimization of treatment effectiveness in diverse populations and may prov
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ef744ea7d8a527c54a0102e94b066d4
https://pubmed.ncbi.nlm.nih.gov/34562957
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7
A human osteosarcoma cell line expressing herpes simplex type-1 thymidine kinase: studies with radiolabeled (E)-5-(2-iodovinyl)-2′-fluoro-2′-deoxyuridine
Autor: Weili Duan, Kevin W. Morin, Alexander J.B. McEwan, Leonard I. Wiebe, Edward E. Knaus
Publikováno v: Nuclear Medicine and Biology. 32:459-464
Introduction ( E )-5-(2-Iodovinyl)-2′-fluoro-2′-deoxyuridine (IVFRU) is a pyrimidine nucleoside analogue that accumulates selectively in murine cells expressing herpes simplex type-1 thymidine kinase (HSV-1 TK). The uptake of [ 125 I]IVFRU in hum
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad473a9ec5d2543d37dace51634fb322
https://doi.org/10.1016/j.nucmedbio.2005.03.006
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8
Imaging expression of adenoviral HSV1-tk suicide gene transfer using the nucleoside analogue FIRU
Autor: Edward E. Knaus, Peter H. Cox, Leonard I. Wiebe, Ebrahim Naimi, Cees C J Avezaat, Peter A. E. Sillevis Smitt, M.J. Driesse, Magda Bijster, Kevin W. Morin, Ronald Vogels, Marion de Jong, Dharmin Nanda, Willem H. Bakker, Menzo J. E. Havenga
Publikováno v: European Journal of Nuclear Medicine and Molecular Imaging, 29, 7, pp. 939-47
European Journal of Nuclear Medicine, 29(7), 939-947. Springer-Verlag
European Journal of Nuclear Medicine and Molecular Imaging, 29, 939-47
Substrates for monitoring HSV1-tk gene expression include uracil and acycloguanosine derivatives.The most commonly used uracil derivative to monitor HSV1-tk gene transfer is 1-(2-fluoro-2-deoxy-β-D-arabinofuranosyl)-5-[*I]iodouracil (fialuridine; I*
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44f182206f9f5ff189bb23ebb037aaa3
https://hdl.handle.net/2066/185358
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9
Reporter gene imaging: Effects of ganciclovir treatment on nucleoside uptake, hypoxia and perfusion in a murine gene therapy tumour model that expresses herpes simplex type-1 thymidine kinase
Autor: Leonard I. Wiebe, E. E. Knaus, Alexander J.B. McEwan, H. Xia, Kevin W. Morin
Publikováno v: Nuclear Medicine Communications. 21:129-137
Perfusion, hypoxia and nucleoside uptake during ganciclovir therapy were determined in a murine HSV-1 TK-expressing tumour model (KBALB-STK). HSV-1 TK mRNA transcription in this cell line was confirmed by RT-PCR. BALB/c mice bearing KBALB-STK tumours
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f81798efd8bbb56d68cdf1ea8eda8c10
https://doi.org/10.1097/00006231-200002000-00002
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10
A Comparative Study of 5-ethyl-2′-Deoxyuridine and Selected Lipophilic 5,6-Dihydro Double/Triple Prodrugs
Autor: Leonard I. Wiebe, Edward E. Knaus, Abdol Majid Cheraghali, E. De Clercq, Kevin W. Morin, Rakesh K. Kumar
Publikováno v: Antiviral Chemistry and Chemotherapy. 6:356-364
(+)- Trans-(5R,6R)-5-bromo-5-ethyl-6-ethoxy-5,6-dihydro-5′-O-valeryl-2′-deoxyuridine (3) and (+)- trans-(5R,6R)-5-bromo-5-ethyl-6-ethoxy-5,6-dihydro-3′,5′-di-O-valery[-2′-deoxyuridine (4) were synthesized in 55% and 8.6% yield, respectively
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::90c20fc98b7f0e030c832aa583ed1293
https://doi.org/10.1177/095632029500600602
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