Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Kevin W Trotter"'
Publikováno v:
eLife, Vol 7 (2018)
The Glucocorticoid Receptor (GR) alters transcriptional activity in response to hormones by interacting with chromatin at GR binding sites (GBSs) throughout the genome. Our work in human breast cancer cells identifies three classes of GBSs with disti
Externí odkaz:
https://doaj.org/article/f5c6465725fc45508379b37933ff4a19
Autor:
Christopher A Lavender, Kimberly R Cannady, Jackson A Hoffman, Kevin W Trotter, Daniel A Gilchrist, Brian D Bennett, Adam B Burkholder, Craig J Burd, David C Fargo, Trevor K Archer
Publikováno v:
PLoS Genetics, Vol 12, Iss 8, p e1006224 (2016)
Antisense transcription is a prevalent feature at mammalian promoters. Previous studies have primarily focused on antisense transcription initiating upstream of genes. Here, we characterize promoter-proximal antisense transcription downstream of gene
Externí odkaz:
https://doaj.org/article/2f0d439aff5d4fce89f99d8a68cb7f3b
Autor:
Farideh Shafiee-Kermani, Skyla T. Carney, Dereje Jima, Utibe C. Utin, LaNeisha B. Farrar, Melvin O. Oputa, Marcono R. Hines, H. Karimi Kinyamu, Kevin W. Trotter, Trevor K. Archer, Cathrine Hoyo, Beverly H. Koller, Stephen J. Freedland, Delores J. Grant
Publikováno v:
Epigenetics, Vol 16, Iss 3, Pp 289-299 (2021)
Studies have suggested that abrogated expression of detoxification enzymes, UGT2B15 and UGT2B17, are associated with prostate tumour risk and progression. We investigated the role of EGF on the expression of these enzymes since it interacts with sign
Externí odkaz:
https://doaj.org/article/b07d19108d254966ae0dcb681885e3bb
Autor:
Nolan G. Gokey, James M. Ward, Eric J. Milliman, Leesa J. Deterding, Kevin W. Trotter, Trevor K. Archer
The Chromatosome superstructure, comprised of core histone containing nucleosomes and linker histones, act in concert as physical barriers to genetic material in the mammalian nucleus to trans-acting factors. Appropriate arrangement, composition, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4dab22b753a4b3ef14ea5c39aaf37b4
https://doi.org/10.1101/2023.05.14.540702
https://doi.org/10.1101/2023.05.14.540702
Autor:
Cathrine Hoyo, Delores J Grant, Farideh Shafiee-Kermani, Dereje D. Jima, H. Karimi Kinyamu, Stephen J. Freedland, Beverly H. Koller, Kevin W. Trotter, LaNeisha B Farrar, Trevor K. Archer, Marcono R Hines, Skyla T. Carney, Melvin O Oputa, Utibe C Utin
Publikováno v:
Epigenetics. 16:289-299
Studies have suggested that abrogated expression of detoxification enzymes, UGT2B15 and UGT2B17, are associated with prostate tumour risk and progression. We investigated the role of EGF on the expression of these enzymes since it interacts with sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2be236e08ecc5e5e93a9ceaa4adee09
https://doi.org/10.1080/15592294.2020.1795601
https://doi.org/10.1080/15592294.2020.1795601
Autor:
Farideh, Shafiee-Kermani, Skyla T, Carney, Dereje, Jima, Utibe C, Utin, LaNeisha B, Farrar, Melvin O, Oputa, Marcono R, Hines, H Karimi, Kinyamu, Kevin W, Trotter, Trevor K, Archer, Cathrine, Hoyo, Beverly H, Koller, Stephen J, Freedland, Delores J, Grant
Publikováno v:
Epigenetics
Studies have suggested that abrogated expression of detoxification enzymes, UGT2B15 and UGT2B17, are associated with prostate tumour risk and progression. We investigated the role of EGF on the expression of these enzymes since it interacts with sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b40648967ea5831e85c4348df6523974
https://pubmed.ncbi.nlm.nih.gov/32660355
https://pubmed.ncbi.nlm.nih.gov/32660355
Publikováno v:
Communications Biology
Communications Biology, Vol 3, Iss 1, Pp 1-11 (2020)
Communications Biology, Vol 3, Iss 1, Pp 1-11 (2020)
Steroid hormone receptors such as the Glucocorticoid Receptor (GR) mediate transcriptional responses to hormones and are frequently targeted in the treatment of human diseases. Experiments using bulk populations of cells have provided a detailed pict
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0c24075b09989c325d17b6798eb19e
https://doi.org/10.1038/s42003-020-0837-0
https://doi.org/10.1038/s42003-020-0837-0
Autor:
Kevin W. Trotter, Trevor K Archer, Jackson Andrew Hoffman, James M. Ward, Christopher R Day, Joseph Rodriguez
Publikováno v:
Journal of the Endocrine Society
Synthetic glucocorticoids such as Dexamethasone (Dex) are widely prescribed drugs used to treat a variety of human diseases including auto-immune disorders, asthma, cancer, and COVID-19. The transcriptional response to glucocorticoids is elicited by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b1341b3ed95ab22c0fd98ecbf74809
https://doi.org/10.1210/jendso/bvab048.1021
https://doi.org/10.1210/jendso/bvab048.1021
Publikováno v:
Molecular and Cellular Biology. 37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f888d0edced5f1b77200fa4ccc0fb69
https://doi.org/10.1128/mcb.00348-17
https://doi.org/10.1128/mcb.00348-17