Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Kevin W Johnson"'
Autor:
Liansheng Liu, Elaine F Papa, Mark S Dooner, Jason T Machan, Kevin W Johnson, Laura R Goldberg, Peter J Quesenberry, Gerald A Colvin
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31300 (2012)
Long-term hematopoietic stem cells (LT-HSC) and short-term hematopoietic stem cells (ST-HSC) have been characterized as having markedly different in vivo repopulation, but similar in vitro growth in liquid culture. These differences could be due to d
Externí odkaz:
https://doaj.org/article/6b71fcbe74f54d6c8738be9f8025d77d
Autor:
Amanda Trent, Geoff Hodge, Steve Kunitake, Kevin W. Johnson, Conor O’Malley, Aaron Gassman, Anna Brown, Jyostna Ivatury
Publikováno v:
Cell and Gene Therapy Insights. 5:1195-1205
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a020e00c04c494df752c3b4fa996bbe
https://doi.org/10.18609/cgti.2019.125
https://doi.org/10.18609/cgti.2019.125
Autor:
Kevin W. Johnson, Peter Fuller, Sujal V. Deshmukh, Fang He, Peter Goldenblatt, Lauren Dorosh, Hongbo Zeng, Jason D. Brubaker, Luis E. Torres, Tony Siu, Fiona Elwood, Charles A. Lesburg, Sangita B. Patel, Duan Liu, Elma Kadic, Christopher J. Dinsmore, Xavier Fradera, Lynsey Shaffer, Jonathan R. Young, Lily Y. Moy, Feng Shi, Carla Alpert, Joel A. Klappenbach, Joshua Close, Rafael Fernandez, Hongshi Yu, Nathan Bays, Dawn M. Mampreian
Publikováno v:
Journal of Medicinal Chemistry. 60:9676-9690
The discovery of a potent selective low dose Janus kinase 1 (JAK1) inhibitor suitable for clinical evaluation is described. As part of an overall goal to minimize dose, we pursued a medicinal chemistry strategy focused on optimization of key paramete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6959a9f84f358dff1679660f1f0b87e
https://doi.org/10.1021/acs.jmedchem.7b01135
https://doi.org/10.1021/acs.jmedchem.7b01135
Autor:
Gerri J. Dooner, Gerald A. Colvin, Michael Del Tatto, Peter J. Quesenberry, Kevin W. Johnson, Mark S. Dooner
Publikováno v:
Stem Cells and Development. 19:453-460
Primitive marrow lineage-negative rhodamine low and Hoechst low (LRH) stem cells isolated on the basis of quiescence respond to the cytokines thrombopoietin, FLT3L, and steel factor by synchronously progressing through cell cycle. We have now profile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceb3512f48d9dbc3be18d82911e51a56
https://doi.org/10.1089/scd.2009.0283
https://doi.org/10.1089/scd.2009.0283
Autor:
Kevin W. Johnson, Gerald A. Colvin, Kenneth Greer, Mark S. Dooner, Sam Faradyan, Jason M. Aliotta, Deborah Greer, Gerri J. Dooner, Mehrdad Adedi, Peter J. Quesenberry, Luiz M. Kolankiewicz, Paulette Ferland, Jeffrey Pimentel, Michael A. Passero, Napoleon Puente, Elaine L. Bearer, Fermín Sánchez-Guijo
Publikováno v:
Stem Cells. 25:2245-2256
Numerous animal studies have demonstrated that adult marrow-derived cells can contribute to the cellular component of the lung. Lung injury is a major variable in this process; however, the mechanism remains unknown. We hypothesize that injured lung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8b80ea8b4f5303100ee44b6671301c
https://doi.org/10.1634/stemcells.2007-0128
https://doi.org/10.1634/stemcells.2007-0128
Autor:
Deborah Greer, Mehrdad Abedi, Bethany M. Foster, Scott D. McLean, Gerald A. Colvin, Kyle D. Wood, Kevin W. Johnson
Publikováno v:
British Journal of Haematology. 138:792-801
It has previously been shown that bone marrow cells contribute to skeletal muscle regeneration, but the nature of marrow cell(s) involved in this process is unknown. We used an immunocompetent and an immunocompromised model of bone marrow transplanta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18711e70c035c60bfbfc75901458eb60
https://doi.org/10.1111/j.1365-2141.2007.06720.x
https://doi.org/10.1111/j.1365-2141.2007.06720.x
Autor:
Julian D. Down, Rob E. Ploemacher, Mary E. White-Scharf, Kevin W. Johnson, Elwin J. C. Rombouts, Joachim Baumgart, Kenol Etienne, G.Robbin Westerhof
Publikováno v:
Biology of Blood and Marrow Transplantation. 10:236-245
Treosulfan (l-threitol-1,4-bismethanesulfonate) is an alkylating agent with routine clinical application in the treatment of ovarian cancer. In this murine study we show that this drug also has the ability to deplete primitive hematopoietic stem cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5685921832d0126d4bd555fb3db44878
https://doi.org/10.1016/j.bbmt.2003.11.004
https://doi.org/10.1016/j.bbmt.2003.11.004
Autor:
Maria Denaro, Peter B. Morgan, Clive Patience, Angela Sullivan, Stuart L. Houser, Kevin W. Johnson, Mary E. White-Scharf, Julian D. Down, Göran Andersson
Publikováno v:
Molecular Therapy. 8(3):385-391
We have investigated whether a state of tolerance toward EGFP-expressing skin tissue can be induced by prior establishment of EGFP molecular chimerism by transplant of gene-transduced bone marrow in mice. Irradiated (10 Gy) C57BL/6J mice were transpl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1118934af2b5dd525eb00d545bd8b690
Autor:
Kevin W, Johnson, Rob, Schnepp
Publikováno v:
JEMS : a journal of emergency medical services. 39(3)
EMS responders to hazmat incidents face significant challenges; however, integration of medical care providers into the planning process for hazmat incidents can facilitate a more efficient response. The competencies found in NFPA 473 provide thoroug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db56ccc2c5c0158e47b521bc3835b419
https://pubmed.ncbi.nlm.nih.gov/24724334
https://pubmed.ncbi.nlm.nih.gov/24724334
Autor:
Victor M. Morales, Andreas Christ, Suzanne M. Watt, Hyun S. Kim, Kevin W. Johnson, Nalan Utku, Ana M. Texieira, Atsushi Mizoguchi, Emiko Mizoguchi, Gary J. Russell, Sara E. Russell, Atul K. Bhan, Gordon J. Freeman, Richard S. Blumberg
Publikováno v:
The Journal of Immunology. 163:1363-1370
Human small intestinal intraepithelial lymphocytes (iIEL) are a unique population of CD8αβ+ TCR-αβ+ but CD28− T lymphocytes that may function in intestinal epithelial cell immunosurveillance. In an attempt to define novel cell surface molecules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::819caa5ae853e0be1839b1ba467432bd
https://doi.org/10.4049/jimmunol.163.3.1363
https://doi.org/10.4049/jimmunol.163.3.1363