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Autor:
Lalitha Tadala, Dorothee Langenbach, Mirjam Dannborg, Ramón Cervantes-Rivera, Atin Sharma, Kevin Vieth, Lisa M. Rieckmann, Alkwin Wanders, David A. Cisneros, Andrea Puhar
Publikováno v:
Tadala, L, Langenbach, D, Dannborg, M, Cervantes-Rivera, R, Sharma, A, Vieth, K, Rieckmann, L M, Wanders, A, Cisneros, D A & Puhar, A 2022, ' Infection-induced membrane ruffling initiates danger and immune signaling via the mechanosensor PIEZO1 ', Cell reports, vol. 40, no. 6, 111173 . https://doi.org/10.1016/j.celrep.2022.111173
Microorganisms are generally sensed by receptors recognizing microbial molecules, which evoke changes in cellular activities and gene expression. Bacterial pathogens induce secretion of the danger signal ATP as an early alert response of intestinal e