Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Kevin V Lemley"'
Autor:
Kevin V Lemley, Serena M Bagnasco, Cynthia C Nast, Laura Barisoni, Catherine M Conway, Stephen M Hewitt, Peter X K Song
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157148 (2016)
OBJECTIVE:Most predictive models of kidney disease progression have not incorporated structural data. If structural variables have been used in models, they have generally been only semi-quantitative. METHODS:We examined the predictive utility of qua
Externí odkaz:
https://doaj.org/article/5a0226df1c314616a847c2674b2b826b
Autor:
Stefano Da Sacco, Kevin V Lemley, Sargis Sedrakyan, Ilenia Zanusso, Astgik Petrosyan, Janos Peti-Peterdi, James Burford, Roger E De Filippo, Laura Perin
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81812 (2013)
Amniotic fluid is in continuity with multiple developing organ systems, including the kidney. Committed, but still stem-like cells from these organs may thus appear in amniotic fluid. We report having established for the first time a stem-like cell p
Externí odkaz:
https://doaj.org/article/d8ec7bd9f3b14f6da062530c581abef7
Autor:
Laura Perin, Sargis Sedrakyan, Stefano Giuliani, Stefano Da Sacco, Gianni Carraro, Liron Shiri, Kevin V Lemley, Michael Rosol, Sam Wu, Anthony Atala, David Warburton, Roger E De Filippo
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9357 (2010)
Acute Tubular Necrosis (ATN) causes severe damage to the kidney epithelial tubular cells and is often associated with severe renal dysfunction. Stem-cell based therapies may provide alternative approaches to treating of ATN. We have previously shown
Externí odkaz:
https://doaj.org/article/7e6d4c68565a4a6e9578ee83bdb989b1
Autor:
Georgina Gyarmati, Urvi Nikhil Shroff, Audrey Izuhara, Xiaogang Hou, Stefano Da Sacco, Sargis Sedrakyan, Kevin V. Lemley, Kerstin Amann, Laura Perin, János Peti-Peterdi
Publikováno v:
JCI Insight, Vol 7, Iss 1 (2022)
Alport syndrome (AS) is a genetic disorder caused by mutations in type IV collagen that lead to defective glomerular basement membrane, glomerular filtration barrier (GFB) damage, and progressive chronic kidney disease. While the genetic basis of AS
Externí odkaz:
https://doaj.org/article/bd42a6b6676047dcb9c617b3480935cc
Autor:
Khadija Banu, Qisheng Lin, John M. Basgen, Marina Planoutene, Chengguo Wei, Anand C. Reghuvaran, Xuefei Tian, Hongmei Shi, Felipe Garzon, Aitor Garzia, Nicholas Chun, Arun Cumpelik, Andrew D. Santeusanio, Weijia Zhang, Bhaskar Das, Fadi Salem, Li Li, Shuta Ishibe, Lloyd G. Cantley, Lewis Kaufman, Kevin V. Lemley, Zhaohui Ni, John Cijiang He, Barbara Murphy, Madhav C. Menon
Publikováno v:
JCI Insight, Vol 6, Iss 19 (2021)
Herein, we report that Shroom3 knockdown, via Fyn inhibition, induced albuminuria with foot process effacement (FPE) without focal segmental glomerulosclerosis (FSGS) or podocytopenia. Interestingly, knockdown mice had reduced podocyte volumes. Human
Externí odkaz:
https://doaj.org/article/48caabe5bbcf4213b0f25719c459b46d
Autor:
Kevin V. Lemley
Publikováno v:
Glomerular Diseases (2021)
Externí odkaz:
https://doaj.org/article/c744adb9e989444e8619b859d69291c1
Autor:
Tarak Srivastava, Katherine M. Dell, Kevin V. Lemley, Debbie S. Gipson, Frederick J. Kaskel, Kevin Edward Meyers, Christian Faul, Ayelet Goldhaber, LauraJane Pehrson, Howard Trachtman
Publikováno v:
Glomerular Diseases. 2:176-183
Introduction: Minimal change disease in childhood can follow a frequently relapsing or steroid-dependent course in up to 40% of cases. Second-line immunosuppressive medications that are used to manage these patients are associated with significant ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::607f0c46fe65082e511ccd0c02f490c2
https://doi.org/10.1159/000525587
https://doi.org/10.1159/000525587
Autor:
Astgik Petrosyan, Valentina Villani, Paola Aguiari, Matthew E. Thornton, Yizhou Wang, Alex Rajewski, Shengmei Zhou, Paolo Cravedi, Brendan H. Grubbs, Roger E. De Filippo, Sargis Sedrakyan, Kevin V. Lemley, Marie Csete, Stefano Da Sacco, Laura Perin
Publikováno v:
Advanced Science.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2db8be893e550e37e7ecc47e868475d
https://doi.org/10.1002/advs.202206787
https://doi.org/10.1002/advs.202206787
Autor:
William A. Primack, Robert L. Chevalier, Aaron Friedman, Kevin V. Lemley, Victoria F. Norwood, George J. Schwartz, Douglas Silverstein, Frederick Kaskel
Publikováno v:
Pediatric Nephrology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2e701530f25cebbd6e7aa7aa11d149a
https://doi.org/10.1007/s00467-022-05838-1
https://doi.org/10.1007/s00467-022-05838-1
Autor:
Cheryl L. Tran, Yujie Wang, Jonathan P. Troost, Jen Jar Lin, Sangeeta Hingorani, Kimberly J. Reidy, Kevin E.C. Meyers, Howard Trachtman, Larry A. Greenbaum, Tarak Srivastava, Chia-shi Wang, Kevin V. Lemley, Christine B. Sethna, Debbie S. Gipson, Keisha L. Gibson, Katherine MacRae Dell, Frederick J. Kaskel
Publikováno v:
Pediatr Nephrol
Pediatric patients with nephrotic syndrome take medications long-term with significant toxicity and complex regimens, yet data on medication adherence are limited.In a multicenter observational study of patients with nephrotic syndrome, NEPTUNE (NCT0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d1ee5ac56b4774e5ccfe3e8a54e46d8
https://doi.org/10.1007/s00467-021-05176-8
https://doi.org/10.1007/s00467-021-05176-8