Zobrazeno 1 - 10
of 239
pro vyhledávání: '"Kevin V Lemley"'
Autor:
Tarak Srivastava, Katherine M. Dell, Kevin V. Lemley, Debbie S. Gipson, Frederick J. Kaskel, Kevin Edward Meyers, Christian Faul, Ayelet Goldhaber, LauraJane Pehrson, Howard Trachtman
Publikováno v:
Glomerular Diseases, Pp 1-8 (2022)
Introduction: Minimal change disease in childhood can follow a frequently relapsing or steroid-dependent course in up to 40% of cases. Second-line immunosuppressive medications that are used to manage these patients are associated with significant ad
Externí odkaz:
https://doaj.org/article/47cf391d09624317bd22d0ca8697b20f
Autor:
Shannon L. Murphy, John D. Mahan, Jonathan P. Troost, Tarak Srivastava, Amy J. Kogon, Yi Cai, T. Keefe Davis, Hilda Fernandez, Alessia Fornoni, Rasheed A. Gbadegesin, Emily Herreshoff, Pietro A. Canetta, Patrick H. Nachman, Bryce B. Reeve, David T. Selewski, Christine B. Sethna, Chia-shi Wang, Sharon M. Bartosh, Debbie S. Gipson, Katherine R. Tuttle, Ali Gharavi, Wooin Ahn, Gerald B. Appel, Rupali S. Avasare, Revekka Babayev, Ibrahim Batal, Andrew S. Bomback, Eric Brown, Eric S. Campenot, Pietro Canetta, Brenda Chan, Vivette D. D’Agati, Bartosz Foroncewicz, Gian Marco Ghiggeri, William H. Hines, Namrata G. Jain, Krzysztof Kiryluk, Fangming Lin, Francesca Lugani, Maddalena Marasa, Glen Markowitz, Sumit Mohan, Krzysztof Mucha, Thomas L. Nickolas, Jai Radhakrishnan, Maya K. Rao, Renu Regunathan-Shenk, Simone Sanna-Cherchi, Dominick Santoriello, Michael B. Stokes, Natalie Yu, Anthony M. Valeri, Ronald Zviti, Larry A. Greenbaum, William E. Smoyer, Amira Al-Uzri, Isa Ashoor, Diego Aviles, Rossana Baracco, John Barcia, Sharon Bartosh, Craig Belsha, Michael C. Braun, Aftab Chishti, Donna Claes, Carl Cramer, Keefe Davis, Elif Erkan, Daniel Feig, Michael Freundlich, Melisha Hanna, Guillermo Hidalgo, Amrish Jain, Myda Khalid, Mahmoud Kallash, MD, Jerome C. Lane, John Mahan, Nisha Mathews, Carla Nester, Cynthia Pan, Hiren Patel, Adelaide Revell, Rajasree Sreedharan, Julia Steinke, Scott E. Wenderfer, Craig S. Wong, Ronald Falk, William Cook, Vimal Derebail, Agnes Fogo, Adil Gasim, Todd Gehr, Raymond Harris, Jason Kidd, Louis-Philippe Laurin, Will Pendergraft, Vincent Pichette, Thomas Brian Powell, Matthew B. Renfrow, Virginie Royal, Lawrence B. Holzman, Sharon Adler, Charles Alpers, Raed Bou Matar, Elizabeth Brown, Michael Choi, Katherine M. Dell, Ram Dukkipati, Fernando C. Fervenza, Crystal Gadegbeku, Patrick Gipson, Leah Hasely, Sangeeta Hingorani, Michelle A. Hladunewich, Jonathan Hogan, J. Ashley Jefferson, Kenar Jhaveri, Duncan B. Johnstone, Frederick Kaskel, Amy Kogan, Jeffrey Kopp, Kevin V. Lemley, Laura Malaga- Dieguez, Kevin Meyers, Alicia Neu, Michelle Marie O'Shaughnessy, John F. O’Toole, Rulan Parekh, Heather Reich, Kimberly Reidy, Helbert Rondon, Kamalanathan K. Sambandam, John R. Sedor, Jeffrey Schelling, John C. Sperati, Agnes Swiatecka-Urban, Howard Trachtman, Joseph Weisstuch, Olga Zhdanova, Brenda Gillespie, Matthias Kretzler, Bruce M. Robinson, Laura Mariani, Matthew Wladkowski, Lisa M. Guay-Woodford
Publikováno v:
Kidney International Reports, Vol 5, Iss 10, Pp 1679-1689 (2020)
Introduction: Prior cross-sectional studies suggest that health-related quality of life (HRQOL) worsens with more severe glomerular disease. This longitudinal analysis was conducted to assess changes in HRQOL with changing disease status. Methods: Cu
Externí odkaz:
https://doaj.org/article/22aaf2057cd54d10aa49074d880c6040
Autor:
Debbie S. Gipson, Howard Trachtman, Anne Waldo, Keisha L. Gibson, Sean Eddy, Katherine M. Dell, Tarak Srivastava, Kevin V. Lemley, Larry A. Greenbaum, Sangeeta Hingorani, Kevin E. Meyers, Frederick J. Kaskel, Kimberly J. Reidy, Christine B. Sethna, Cheryl L. Tran, Chia-shi Wang, Katherine R. Tuttle, Gia Oh, Alicia M. Neu, Elizabeth Brown, Jen-Jar Lin, Jennifer Lai Yee, Therese M. Roth, Jonathan P. Troost, Brenda W. Gillespie, Matthew G. Sampson, Matthias Kretzler, Wenjun Ju
Publikováno v:
Kidney International Reports, Vol 5, Iss 4, Pp 414-425 (2020)
Introduction: Childhood-onset nephrotic syndrome has a variable clinical course. Improved predictive markers of long-term outcomes in children with nephrotic syndrome are needed. This study tests the association between baseline urinary epidermal gro
Externí odkaz:
https://doaj.org/article/0ec9bfee819e47e6a0c27426843af311
Autor:
Georgina Gyarmati, Urvi Nikhil Shroff, Audrey Izuhara, Xiaogang Hou, Stefano Da Sacco, Sargis Sedrakyan, Kevin V. Lemley, Kerstin Amann, Laura Perin, János Peti-Peterdi
Publikováno v:
JCI Insight, Vol 7, Iss 1 (2022)
Alport syndrome (AS) is a genetic disorder caused by mutations in type IV collagen that lead to defective glomerular basement membrane, glomerular filtration barrier (GFB) damage, and progressive chronic kidney disease. While the genetic basis of AS
Externí odkaz:
https://doaj.org/article/bd42a6b6676047dcb9c617b3480935cc
Autor:
Khadija Banu, Qisheng Lin, John M. Basgen, Marina Planoutene, Chengguo Wei, Anand C. Reghuvaran, Xuefei Tian, Hongmei Shi, Felipe Garzon, Aitor Garzia, Nicholas Chun, Arun Cumpelik, Andrew D. Santeusanio, Weijia Zhang, Bhaskar Das, Fadi Salem, Li Li, Shuta Ishibe, Lloyd G. Cantley, Lewis Kaufman, Kevin V. Lemley, Zhaohui Ni, John Cijiang He, Barbara Murphy, Madhav C. Menon
Publikováno v:
JCI Insight, Vol 6, Iss 19 (2021)
Herein, we report that Shroom3 knockdown, via Fyn inhibition, induced albuminuria with foot process effacement (FPE) without focal segmental glomerulosclerosis (FSGS) or podocytopenia. Interestingly, knockdown mice had reduced podocyte volumes. Human
Externí odkaz:
https://doaj.org/article/48caabe5bbcf4213b0f25719c459b46d
Autor:
Kevin V. Lemley
Publikováno v:
Glomerular Diseases (2021)
Externí odkaz:
https://doaj.org/article/c744adb9e989444e8619b859d69291c1
Autor:
Howard Trachtman, Debbie S. Gipson, Kevin V. Lemley, Jonathan P. Troost, Christian Faul, Debra J. Morrison, Suzanne M. Vento, Dong-hyun Ahn, Judith D. Goldberg
Publikováno v:
Frontiers in Pediatrics, Vol 7 (2019)
Objective: We conducted this study to test the hypothesis that plasma zonulin levels are elevated in pediatric patients with nephrotic syndrome compared to healthy controls.Study Design: Plasma zonulin levels were measured by ELISA in 114 children en
Externí odkaz:
https://doaj.org/article/304920b07fa345478de8e653c7f01827
Autor:
Astgik Petrosyan, Valentina Villani, Paola Aguiari, Matthew E. Thornton, Yizhou Wang, Alex Rajewski, Shengmei Zhou, Paolo Cravedi, Brendan H. Grubbs, Roger E. De Filippo, Sargis Sedrakyan, Kevin V. Lemley, Marie Csete, Stefano Da Sacco, Laura Perin
Publikováno v:
Advanced Science.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2db8be893e550e37e7ecc47e868475d
https://doi.org/10.1002/advs.202206787
https://doi.org/10.1002/advs.202206787
Autor:
William A. Primack, Robert L. Chevalier, Aaron Friedman, Kevin V. Lemley, Victoria F. Norwood, George J. Schwartz, Douglas Silverstein, Frederick Kaskel
Publikováno v:
Pediatric Nephrology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2e701530f25cebbd6e7aa7aa11d149a
https://doi.org/10.1007/s00467-022-05838-1
https://doi.org/10.1007/s00467-022-05838-1
Autor:
Cheryl L. Tran, Yujie Wang, Jonathan P. Troost, Jen Jar Lin, Sangeeta Hingorani, Kimberly J. Reidy, Kevin E.C. Meyers, Howard Trachtman, Larry A. Greenbaum, Tarak Srivastava, Chia-shi Wang, Kevin V. Lemley, Christine B. Sethna, Debbie S. Gipson, Keisha L. Gibson, Katherine MacRae Dell, Frederick J. Kaskel
Publikováno v:
Pediatr Nephrol
Pediatric patients with nephrotic syndrome take medications long-term with significant toxicity and complex regimens, yet data on medication adherence are limited.In a multicenter observational study of patients with nephrotic syndrome, NEPTUNE (NCT0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d1ee5ac56b4774e5ccfe3e8a54e46d8
https://doi.org/10.1007/s00467-021-05176-8
https://doi.org/10.1007/s00467-021-05176-8