Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kevin Uranker"'
Autor:
Charlene S Dezzutti, Elizabeth R Brown, Bernard Moncla, Julie Russo, Marilyn Cost, Lin Wang, Kevin Uranker, Ratiya P Kunjara Na Ayudhya, Kara Pryke, Jim Pickett, Marc-André Leblanc, Lisa C Rohan
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48328 (2012)
Because lubricants may decrease trauma during coitus, it is hypothesized that they could aid in the prevention of HIV acquisition. Therefore, safety and anti-HIV-1 activity of over-the-counter (OTC) aqueous- (n = 10), lipid- (n = 2), and silicone-bas
Externí odkaz:
https://doaj.org/article/51a4153809584260b31cd2249df68f78
Autor:
Ayman Akil, Lisa C. Rohan, Kevin Uranker, Charlene S. Dezzutti, Bernard J. Moncla, Hrushikesh Agashe, Sharon L. Hillier, Brid Devlin, Yuan Shi
Publikováno v:
Pharmaceutical Research. 32:458-468
To develop polymeric films containing dual combinations of anti-HIV drug candidate tenofovir, maraviroc and dapivirine for vaginal application as topical microbicides.A solvent casting method was used to manufacture the films. Solid phase solubility
Autor:
Katherine E. Bunge, Ingrid Macio, Sharon L. Hillier, Nicola Richardson-Harman, Kevin Uranker, Charlene S. Dezzutti
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 63:548-554
OBJECTIVE Ex vivo HIV-1 challenge has been proposed as a bioindicator of microbicide product effectiveness. The objective of this study was to establish optimal parameters for use of female genital tract tissue in this model. DESIGN Ex vivo challenge
Autor:
Marilyn Cost, Lin Wang, David R. Friend, Lisa C. Rohan, J. D. Lynam, Cory Shetler, Kevin Uranker, Charlene S. Dezzutti
Publikováno v:
Journal of Antimicrobial Chemotherapy. 67:2139-2142
Objectives: Coital use of 1% tenofovir gel was shown to be modestly effective at preventing HIV transmission when applied vaginally in the CAPRISA 004 trial. Because the gel is hyperosmolar, which would reduce the integrity of the epithelium and indu
Autor:
Kevin Uranker, Charlene S. Dezzutti, Charles E. Isaacs, Catherine A. Chappell, Weimin Xu, Bernard J. Moncla, Leslie A. Meyn, Sharon L. Hillier
Publikováno v:
American journal of obstetrics and gynecology. 213(2)
Reproductive hormones are known to impact innate mucosal immune function of the lower genital tract. Our objectives were to determine the effect of hormonal status on intrinsic antiviral (herpes simplex virus [HSV]-1, HSV-2, and human immunodeficienc
Autor:
Kevin Uranker, Julie Russo, Charlene S. Dezzutti, Marc-André LeBlanc, Marilyn Cost, Lin Wang, Elizabeth R. Brown, Bernard J. Moncla, Kara Pryke, Lisa C. Rohan, James Pickett, Ratiya Pamela Kunjara Na Ayudhya
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48328 (2012)
PLoS ONE
PLoS ONE
Because lubricants may decrease trauma during coitus, it is hypothesized that they could aid in the prevention of HIV acquisition. Therefore, safety and anti-HIV-1 activity of over-the-counter (OTC) aqueous- (n = 10), lipid- (n = 2), and silicone-bas