Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kevin Sweder"'
Autor:
Kevin Sweder
Publikováno v:
F1000Research, Vol 6 (2017)
The ability of non-genotoxic agents to induce cancer has been documented and clearly requires a reassessment of testing for environmental and human safety. Drug safety testing has historically relied on test batteries designed to detect DNA damage le
Externí odkaz:
https://doaj.org/article/6fe343ad89a442d99890b34e896b5f3a
Autor:
William C. Gunther, Ann Schuermans, John Nicolette, Fabrice Nesslany, Ronald D. Fiedler, Stephen D. Dertinger, Céline Defrain, Laura Custer, Thomas J. Shutsky, Catherine J. Thiffeault, Robert H. Heflich, Paul Sonders, Amanda Giddings, Ljubica Krsmanovic, Javed A. Bhalli, Eleanor C. Wilde, Anthony M. Lynch, James T. MacGregor, Kevin Sweder, Osamu Tajima, Takafumi Kimoto, Andrew Henwood, Jing Shi, Terry Van Doninck, Souk Phonethepswath, Carol Gleason, Bas-jan M. van der Leede, Hans-Werner Vohr, Daniel J. Roberts, Pamela Weller, Azeddine Elhajouji, Yoshie Hiwata, Leon F. Stankowski, Joel Murray, Julia Kenny, Kentaro Tanaka
Publikováno v:
Environmental and Molecular Mutagenesis. 52:690-698
A collaborative international trial was conducted to evaluate the reproducibility and transferability of an in vivo mutation assay based on the enumeration of CD59-negative rat erythrocytes, a phenotype that is indicative of Pig-a gene mutation. Four
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f313510d8a658754853218a9f4fc7a2
https://doi.org/10.1002/em.20672
https://doi.org/10.1002/em.20672
Autor:
Willi Suter, Kristine L. Witt, Elisabeth Lorge, Véronique Thybaud, Dan D. Levy, Kerry L. Dearfield, Gladys Ouedraogo-Arras, Kirk S. Tarlo, Laura Custer, James Harvey, James H. Kim, Michael C. Cimino, Susan D. Hester, David Kirkland, Maik Schuler, Freddy Van Goethem, Martha M. Moore, Kevin Sweder, Andreas Czich, Jan van Benthem
Publikováno v:
Environmental and Molecular Mutagenesis. 52:177-204
Appropriate follow-up actions and decisions are needed when evaluating and interpreting clear positive results obtained in the in vitro assays used in the initial genotoxicity screening battery (i.e., the battery of tests generally required by regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f63ae4d2b7d7d4a81d32d1609a101535
https://doi.org/10.1002/em.20617
https://doi.org/10.1002/em.20617
Autor:
Mel Limson, Kevin Sweder
Publikováno v:
Toxicological Sciences. 113:77-84
The yeast target of rapamycin (Tor) kinases, Tor1 and Tor2, belong to the phosphatidylinositol 3-kinase-related family of proteins, which are involved in the cellular response to DNA damage and changes in nutrient conditions. In contrast to yeast, ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9daeeb364ee251da9735478a96c71554
https://doi.org/10.1093/toxsci/kfp238
https://doi.org/10.1093/toxsci/kfp238