Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Kevin Staras"'
Publikováno v:
Cell Reports, Vol 30, Iss 6, Pp 2006-2017.e3 (2020)
Summary: Vesicle pool properties are known determinants of synaptic efficacy, but their potential role as modifiable substrates in forms of Hebbian plasticity is still unclear. Here, we investigate this using a nanoscale readout of functionally recyc
Externí odkaz:
https://doaj.org/article/e65722ad593a4ead9105636e66b89037
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Integrating information from both the external environment and an organism's internal state is an important aspect of feeding-related decision making. Here, the authors identify a two neuron circuit within the mollusc Lymnaeathat adapts feeding behav
Externí odkaz:
https://doaj.org/article/c2ac0b4e06384921a8ca5bb0cf972c95
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 10, p e1005137 (2016)
We propose a biologically plausible architecture for unsupervised ensemble learning in a population of spiking neural network classifiers. A mixture of experts type organisation is shown to be effective, with the individual classifier outputs combine
Externí odkaz:
https://doaj.org/article/1df95ddd9fbe43f3982ed41576f08527
Autor:
Kevin Staras, Tiago Branco
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 2 (2010)
Presynaptic terminals in hippocampal neurons house functionally distinct vesicle pools, the size, structure and biochemical features of which are major determinants of presynaptic strength and performance. In classical models of synaptic function the
Externí odkaz:
https://doaj.org/article/c18623e411704d3c9c78acdb5c897464
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 4 (2010)
Animals show periods of quiescence interspersed with periods of motor activity. In a number of invertebrate and vertebrate systems, quiescence is achieved by active suppression of motor behavior induced by sensory input or changes in internal state.
Externí odkaz:
https://doaj.org/article/97d5581580df455cbd55d013a8ac63f9
Publikováno v:
Science Advances. 9
Long-term memory formation is energetically costly. Neural mechanisms that guide an animal to identify fruitful associations therefore have important survival benefits. Here, we elucidate a circuit mechanism in Lymnaea , which enables past memory to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b813b348705570e09cc7cc5c25ef48e8
https://doi.org/10.1126/sciadv.add3403
https://doi.org/10.1126/sciadv.add3403
Publikováno v:
eLS
Neural circuits underlying reflex and rhythmic behaviours in molluscs can be understood at the level of single identified neurons. Using these systems, the most important advances have been made in the understanding of the cellular and molecular basi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4967715594862deed5cc97471cf079db
https://doi.org/10.1002/9780470015902.a0029277
https://doi.org/10.1002/9780470015902.a0029277
Autor:
Luca Biasetti, Stephanie Rey, Milena Fowler, Arjuna Ratnayaka, Kate Fennell, Catherine Smith, Karen Marshall, Catherine Hall, Mariana Vargas-Caballero, Louise Serpell, Kevin Staras
Alzheimer’s disease is linked to increased levels of amyloid beta (Aβ) in the brain, but the mechanisms underlying neuronal dysfunction and neurodegeneration remain enigmatic. Here, we investigate whether organizational characteristics of function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f052f99561ba6ca2ea1b14eb671d922a
https://eprints.soton.ac.uk/457169/
https://eprints.soton.ac.uk/457169/
Autor:
Arnd Roth, Marra, Michael Häusser, András Simon, Claudia Racca, Kevin Staras, Arlo Sheridan, Jan Funke, Mehmet Fişek
Large-volume ultrastructural mapping approaches yield detailed circuit wiring diagrams but lack an integrated synaptic activity readout which is essential for functional interpretation of the connectome. Here we resolve this limitation by combining f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b69e1e17eba62ddd527d27e744246bc2
https://doi.org/10.1101/2021.07.07.451278
https://doi.org/10.1101/2021.07.07.451278
Autor:
Takeshi Yoshimatsu, F. Janiak, Miguel Maravall, Michael R. Bale, Kevin Staras, Lucia L. Prieto-Godino, Mingyi Zhou, Philipp Bartel, Thomas Euler, Emilia Komulainen, Tom Baden
In neuroscience, diffraction limited two-photon (2P) microscopy is a cornerstone technique that permits minimally invasive optical monitoring of neuronal activity. However, most conventional 2P microscopes impose significant constraints on the size o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::693efe7260bdd962caf8bbcb87ce8357
https://doi.org/10.21203/rs.3.rs-121292/v1
https://doi.org/10.21203/rs.3.rs-121292/v1