Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Kevin Spelman"'
Publikováno v:
Drugs - Real World Outcomes, Vol 11, Iss 4, Pp 669-678 (2024)
Abstract Background There is a growing interest in products featuring hemp extracts and a demand for more data regarding their safety. To date, there is a paucity of published data on the safety of these products. Methods A retrospective analysis of
Externí odkaz:
https://doaj.org/article/e5bd572f2a394d7dbb1d533adac9d95c
Autor:
Rick Sheridan, Kevin Spelman
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The Covid-19 pandemic has elicited much laboratory and clinical research attention on vaccines, mAbs, and certain small-molecule antivirals against SARS-CoV-2 infection. By contrast, there has been comparatively little attention on plant-derived comp
Externí odkaz:
https://doaj.org/article/6b761645e90045e192a7072871375ad1
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Medicinal plants have been valued for many generations due to their biosynthetic advantages generating pharmacologically active molecules. This is especially the case when it comes to cannabinoids from Cannabis. In these experiments we mimicked typic
Externí odkaz:
https://doaj.org/article/494b39b28bba4652b2427a37b675c943
Publikováno v:
Journal of Restorative Medicine. 6:19-26
Hericium erinaceus, most commonly known as lion’s mane, is an edible fungus, with a long history of use in Traditional Chinese Medicine. The mushroom is abundant in bioactive compounds including β-glucan polysaccharides; hericenones and erinacine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5588c87ba2894ca4078de4f2acd18a4a
https://doi.org/10.14200/jrm.2017.6.0108
https://doi.org/10.14200/jrm.2017.6.0108
Publikováno v:
Journal of Chromatography B. 968:105-111
SIRT6 is a histone deacetylase that has been proposed as a potential therapeutic target for metabolic disorders and the prevention of age-associated diseases. Thus the identification of compounds that modulate SIRT6 activity could be of great therape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b3869ac10bef1b7df9ad2000a0596c
https://doi.org/10.1016/j.jchromb.2014.03.016
https://doi.org/10.1016/j.jchromb.2014.03.016
Autor:
Ara Kirakosyan, Sara L. Warber, M. J. Bogenschutz-Godwin, H. L. Brielmann, Kevin Spelman, James A. Duke, Peter B. Kaufman, Leland J. Cseke
Publikováno v:
Natural Products from Plants ISBN: 9780429125638
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e36060826ba8f1596d8fcc1bf22e5ec1
https://doi.org/10.1201/9781420004472-17
https://doi.org/10.1201/9781420004472-17
Autor:
A. Brizzi, Irving W. Wainer, Claudia Mugnaini, S. Nocerino, Avraham Rosenberg, Kevin Spelman, J. Frazier, Charles J. Frazier, Ruin Moaddel
Publikováno v:
Analytical Biochemistry. 412:85-91
Cannabinoid receptors, CB1 and CB2, are therapeutic targets in the treatment of anxiety, obesity, movement disorders, glaucoma, and pain. We have developed an on-line screening method for CB1 and CB2 ligands, where cellular membrane fragments of a ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4f08c7635263f93c83cbd90b49c65a
https://doi.org/10.1016/j.ab.2010.12.034
https://doi.org/10.1016/j.ab.2010.12.034
Publikováno v:
Phytotherapy Research. 25:1098-1101
Spilanthes spp. are used as traditional herbal medicines in Africa and India to treat malaria. Yet, to date, there are no data on the active constituents or the most effective extraction methods for this indication. The isolated alkylamides, spilanth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bcbb57e680ef33a94f1889ca513ce55
https://doi.org/10.1002/ptr.3395
https://doi.org/10.1002/ptr.3395
Autor:
Edward M. Kwasnik, M. A. Mahendra, T. M. Obasi, Kevin Spelman, J. Morse, R. Aldag, E. J. Williams, A. Hamman
Publikováno v:
Phytotherapy Research. 25:473-483
Many traditional medicines have demonstrated immune activity, however, research has largely neglected their effects on cell adhesion molecules (CAMs). This review reports on extracts from 37 medicinal plant species, similar to or replicating traditio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3476f1612036b04c6aa1016a41d33142
https://doi.org/10.1002/ptr.3350
https://doi.org/10.1002/ptr.3350
Publikováno v:
Toxicology. 278:140-159
Many of the botanical "immunomodulators", a class of herbal medicines widely recognized in traditional medical systems such as Chinese Medicine (TCM) and Ayurvedic Medicine, alter immune function and may offer clinically relevant therapeutics or lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d6a471a14994e547aea2028d6f853c1
https://doi.org/10.1016/j.tox.2009.09.020
https://doi.org/10.1016/j.tox.2009.09.020