Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Kevin Sharp"'
Autor:
Nell Maltman, Janna Guilfoyle, Kritika Nayar, Gary E. Martin, Molly Winston, Joseph C. Y. Lau, Lauren Bush, Shivani Patel, Michelle Lee, John Sideris, Deborah A. Hall, Lili Zhou, Kevin Sharp, Elizabeth Berry-Kravis, Molly Losh
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
The FMR1 gene in its premutation (PM) state has been linked to a range of clinical and subclinical phenotypes among FMR1 PM carriers, including some subclinical traits associated with autism spectrum disorder (ASD). This study attempted to further ch
Externí odkaz:
https://doaj.org/article/3e5cf5f028824d7f87fae980041a9bb8
Autor:
Heather Bowling, Aditi Bhattacharya, Guoan Zhang, Danyal Alam, Joseph Z. Lebowitz, Nathaniel Bohm-Levine, Derek Lin, Priyangvada Singha, Maggie Mamcarz, Rosemary Puckett, Lili Zhou, Sameer Aryal, Kevin Sharp, Kent Kirshenbaum, Elizabeth Berry-Kravis, Thomas A. Neubert, Eric Klann
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Elevated protein synthesis, and dysregulated mGluR signalling, are documented in fragile X syndrome (FXS) Here the authors use proteomic analysis in a mouse model of FXS, and following mGluR5 stimulation, to identify potential biomarkers for the dise
Externí odkaz:
https://doaj.org/article/0178bf18b8774f1ebc6d3278b69cc089
Autor:
Molly Winston, Kritika Nayar, Emily Landau, Nell Maltman, John Sideris, Lili Zhou, Kevin Sharp, Elizabeth Berry-Kravis, Molly Losh
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Atypical visual attention patterns have been observed among carriers of the fragile X mental retardation gene (FMR1) premutation (PM), with some similarities to visual attention patterns observed in autism spectrum disorder (ASD) and among clinically
Externí odkaz:
https://doaj.org/article/c71150ead39c4420ab3e6b51707829f4
Autor:
Kritika Nayar, Walker McKinney, Abigail L Hogan, Gary E Martin, Chelsea La Valle, Kevin Sharp, Elizabeth Berry-Kravis, Elizabeth S Norton, Peter C Gordon, Molly Losh
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219924 (2019)
The FMR1 premutation (PM) is relatively common in the general population. Evidence suggests that PM carriers may exhibit subtle differences in specific cognitive and language abilities. This study examined potential mechanisms underlying such differe
Externí odkaz:
https://doaj.org/article/bc759a9199ad4aa9b1422b9cca934609
Autor:
Dejan B. Budimirovic, Annette Schlageter, Stela Filipovic-Sadic, Dragana D. Protic, Eran Bram, E. Mark Mahone, Kimberly Nicholson, Kristen Culp, Kamyab Javanmardi, Jon Kemppainen, Andrew Hadd, Kevin Sharp, Tatyana Adayev, Giuseppe LaFauci, Carl Dobkin, Lili Zhou, William Ted Brown, Elizabeth Berry-Kravis, Walter E. Kaufmann, Gary J. Latham
Publikováno v:
Brain Sciences, Vol 10, Iss 10, p 694 (2020)
Fragile X syndrome (FXS) is caused by silencing of the FMR1 gene, which encodes a protein with a critical role in synaptic plasticity. The molecular abnormality underlying FMR1 silencing, CGG repeat expansion, is well characterized; however, delineat
Externí odkaz:
https://doaj.org/article/904cd6972f0b45918585a7ea75116838
Autor:
Stephen M. Smith, Gwenaëlle Douaud, Winfield Chen, Taylor Hanayik, Lloyd T. Elliott, Fidel Alfaro-Almagro, Kevin Sharp
Publikováno v:
Nature neuroscience
UK Biobank is a major prospective epidemiological study, including multimodal brain imaging, genetics and ongoing health outcomes. Previously, we published genome-wide associations of 3,144 brain imaging-derived phenotypes, with a discovery sample of
Autor:
Eric Klann, Janani Priya Venkatasubramani, Elizabeth Berry-Kravis, Aditi Bhattacharya, Kevin Sharp, Amanda C. Kasper, Erin Carmody, Heather Bowling, Chhaya Patole, Sarah Parker Leventer, Kent Kirshenbaum
Publikováno v:
Journal of Proteome Research. 19:3856-3866
Aberrant protein synthesis and protein expression are a hallmark of many conditions ranging from cancer to Alzheimer's. Blood-based biomarkers indicative of changes in proteomes have long been held to be potentially useful with respect to disease pro
Autor:
Joseph C. Y. Lau, Kritika Nayar, Gary E. Martin, Shivani Patel, Lili Zhou, Molly Losh, Elizabeth Berry-Kravis, Lauren Bush, Nell Maltman, Janna Guilfoyle, Michelle Lee, Deborah A. Hall, John Sideris, Molly Winston, Kevin Sharp
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
Frontiers in Psychiatry
Frontiers in Psychiatry
The FMR1 gene in its premutation (PM) state has been linked to a range of clinical and subclinical phenotypes among FMR1 PM carriers, including some subclinical traits associated with autism spectrum disorder (ASD). This study attempted to further ch
Autor:
Kevin Sharp
Publikováno v:
Genetic Engineering & Biotechnology News. 42:22-23
Autor:
John Sideris, Kritika Nayar, Elizabeth Berry-Kravis, Molly Losh, Emily Landau, Molly Winston, Nell Maltman, Lili Zhou, Kevin Sharp
Publikováno v:
Frontiers in Genetics
Frontiers in Genetics, Vol 12 (2021)
Frontiers in Genetics, Vol 12 (2021)
Atypical visual attention patterns have been observed among carriers of the fragile X mental retardation gene (FMR1) premutation (PM), with some similarities to visual attention patterns observed in autism spectrum disorder (ASD) and among clinically