Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kevin S. Lang"'
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT Antibiotic tolerance not only enables bacteria to survive acute antibiotic exposures but also provides bacteria with a window of time in which to develop antibiotic resistance. The increasing prevalence of Campylobacter jejuni isolates resis
Externí odkaz:
https://doaj.org/article/dab49c609c074558adfeaf9f454b7952
Autor:
Zhizhi Wang, Peilong Lu, Dan Ma, Houra Merrikh, Wenqing Xu, Zihe Rao, Xin Li, Christopher N. Merrikh, Kevin S. Lang
Publikováno v:
Nature
Membrane-bound O-acyltransferases (MBOATs) are a superfamily of integral transmembrane enzymes that are found in all kingdoms of life1. In bacteria, MBOATs modify protective cell-surface polymers. In vertebrates, some MBOAT enzymes—such as acyl-coe
Autor:
Kevin S. Lang, Houra Merrikh
Publikováno v:
Cell reports
SUMMARY Conflicts between the replication and transcription machineries have profound effects on chromosome duplication, genome organization, and evolution across species. Head-on conflicts (lagging-strand genes) are significantly more detrimental th
Autor:
Kevin S. Lang, Timothy J. Johnson
Publikováno v:
Plasmid. :17-27
Conjugation plays an important role in the horizontal movement of DNA between bacterial species and even genera. Large conjugative plasmids in Gram-negative bacteria are associated with multi-drug resistance and have been implicated in the spread of
Encounters between transcription and DNA replication machineries lead to conflicts that shape genomes, influence evolution, and lead to genetic diseases in humans. Although unclear why, head-on transcription (lagging strand genes) is especially disru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c98dbaf62019ead33032577ef7b84fbe
https://doi.org/10.1101/154427
https://doi.org/10.1101/154427
Publikováno v:
Environmental sciencetechnology. 49(19)
This study evaluated multiple discharges of treated wastewater on the quantities of antibiotic resistance genes (ARGs) in the Upper Mississippi River. Surface water and treated wastewater samples were collected along the Mississippi River during thre
Autor:
Timothy J. Johnson, Kevin S. Lang
Publikováno v:
Plasmid. 80
Plasmids play an important role in driving the genetic diversity of bacteria. Horizontal gene transfer via plasmids is crucial for the dissemination of antimicrobial resistance genes. Many factors contribute to the persistence of plasmids within bact
Autor:
Jonathan G. Frye, Kristi Kobluk, Klaudyna Borewicz, Janet M. Anderson, Kevin S. Lang, Richard E. Isaacson, Bernadette Rivet, Peter R. Davies, Timothy J. Johnson, Mark D. Englen, Jessica L. Danzeisen, Randall S. Singer
Publikováno v:
Applied and environmental microbiology. 81(10)
IncA/C plasmids are broad-host-range plasmids enabling multidrug resistance that have emerged worldwide among bacterial pathogens of humans and animals. Although antibiotic usage is suspected to be a driving force in the emergence of such strains, fe
Autor:
Christopher N. Merrikh, Kevin S. Lang, Joshua J. Woodward, Alex J. Pollock, Ashley N. Hall, Julia E. Dreifus, Houra Merrikh, Hannah Tabakh, Mark N. Ragheb
Publikováno v:
Cell. 170:787-799.e18
Replication-transcription collisions shape genomes, influence evolution, and promote genetic diseases. Although unclear why, head-on transcription (lagging strand genes) is especially disruptive to replication and promotes genomic instability. Here,
Publikováno v:
Applied and environmental microbiology. 78(9)
The multidrug resistance-encoding plasmids belonging to the IncA/C incompatibility group have recently emerged among Escherichia coli and Salmonella enterica strains in the United States. These plasmids have a unique genetic structure compared to oth