Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kevin S. Harris"'
Autor:
James I Mullins, Laura Heath, James P Hughes, Jessica Kicha, Sheila Styrchak, Kim G Wong, Ushnal Rao, Alexis Hansen, Kevin S Harris, Jean-Pierre Laurent, Deyu Li, Jeffrey H Simpson, John M Essigmann, Lawrence A Loeb, Jeffrey Parkins
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15135 (2011)
The deoxycytidine analog KP1212, and its prodrug KP1461, are prototypes of a new class of antiretroviral drugs designed to increase viral mutation rates, with the goal of eventually causing the collapse of the viral population. Here we present an ext
Externí odkaz:
https://doaj.org/article/9587c765745241c5ad78b355b9453f55
Publikováno v:
Virology. 211:451-461
Poliovirus infection results in a number of host cell changes, including specific alterations in cellular proteins. This study further characterizes the cleavage of a cytoskeletal protein, microtubule-associated protein 4 (MAP-4) and investigates the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54597c28a7d315893ea1ad0d11d259e2
https://doi.org/10.1006/viro.1995.1427
https://doi.org/10.1006/viro.1995.1427
Autor:
Deyu Li, Alexis B. Hansen, Jeffrey Parkins, James P. Hughes, Jeffrey H. Simpson, Kevin S Harris, Ushnal Rao, Kim G. Wong, Lawrence A. Loeb, John M. Essigmann, Jean Pierre Laurent, Laura Heath, Jessica Kicha, James I. Mullins, Sheila Styrchak
Publikováno v:
PLoS ONE
PLoS
PLoS ONE, Vol 6, Iss 1, p e15135 (2011)
PLoS
PLoS ONE, Vol 6, Iss 1, p e15135 (2011)
The deoxycytidine analog KP1212, and its prodrug KP1461, are prototypes of a new class of antiretroviral drugs designed to increase viral mutation rates, with the goal of eventually causing the collapse of the viral population. Here we present an ext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e1b37775eddb5af045a872f6d2dd13
https://pubmed.ncbi.nlm.nih.gov/21264288
https://pubmed.ncbi.nlm.nih.gov/21264288
Autor:
Akhter Molla, Leo W. Barrett, Stephen F. Betz, Kevin Steffy, Kent D. Stewart, Jeffrey R. Huth, Paul L. Richardson, Jean M. Severin, Steve Muchmore, John E. Harlan, Dale J. Kempf, Kevin S. Harris, Edmund D. Matayoshi, Renaldo R. Mendoza, Vincent S. Stoll, Karl A. Walter, Kerry M. Swift, Emily E. Gramling-Evans
Publikováno v:
Journal of computer-aided molecular design. 21(1-3)
Two new proteins of approximately 70 amino acids in length, corresponding to an unnaturally-linked N- and C-helix of the ectodomain of the gp41 protein from the human immunodeficiency virus (HIV) type 1, were designed and characterized. A designed tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a1d4764feb7f89ea896d6983b25aa63
https://pubmed.ncbi.nlm.nih.gov/17294246
https://pubmed.ncbi.nlm.nih.gov/17294246
Publikováno v:
Antiviral research. 67(1)
We report the activities of a novel nucleoside analog against HIV. This nucleoside (KP-1212) is not a chain terminator but exerts its antiviral effects via mutagenesis of the viral genome. Serial passaging of HIV in the presence of KP-1212 causes an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2a99dc3bae6d6f6139c7148885aa24a
https://pubmed.ncbi.nlm.nih.gov/15890415
https://pubmed.ncbi.nlm.nih.gov/15890415
The expression of alternatively spliced mRNAs from genes is an ubiquitous phenomenon in metazoa. A screen for trans-acting factors that alter the expression of alternatively spliced mRNAs reveals that the smg genes of Caenorhabditis elegans participa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21f13477a59676916e14efe39a5adaa
https://europepmc.org/articles/PMC23268/
https://europepmc.org/articles/PMC23268/
Autor:
Jeff Parkins, James P. Hughes, Jean-Pierre Laurent, James I. Mullins, John M. Essigmann, Lawrence A. Loeb, Laura Heath, Deyu Li, Kevin S Harris, Jeffrey H. Simpson
Publikováno v:
Retrovirology
Background The deoxycytidine analog KP1212, and its prodrug KP1461, are prototypes of a new class of antiretroviral drugs designed to increase viral mutation rates, with the goal of eventually causing the collapse of the viral population. KP1212 will
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bca6fdeccc2387df428c16650d522b6
http://europepmc.org/articles/PMC3236977
http://europepmc.org/articles/PMC3236977