Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Kevin S Oh"'
Autor:
Susan G. R. McDuff, Jorg Dietrich, Katelyn M. Atkins, Kevin S. Oh, Jay S. Loeffler, Helen A. Shih
Publikováno v:
Cancer Medicine, Vol 9, Iss 1, Pp 3-11 (2020)
Abstract Purpose The majority of patients with high‐risk lower grade gliomas (LGG) are treated with single‐agent temozolomide (TMZ) and radiotherapy despite three randomized trials showing a striking overall survival benefit with adjuvant procarb
Externí odkaz:
https://doaj.org/article/662e88c523264e38aa8090e31a6883a0
Autor:
Rachel B. Jimenez, MD, Brian M. Alexander, MD, MPH, Anand Mahadevan, MD, Andrzej Niemierko, PhD, Selvan Rajakesari, MD, Nils D. Arvold, MD, Scott R. Floyd, MD, PhD, Kevin S. Oh, MD, Jay S. Loeffler, MD, Helen A. Shih, MD
Publikováno v:
Advances in Radiation Oncology, Vol 2, Iss 3, Pp 391-397 (2017)
Purpose: Stereotactic radiation therapy (SRT) enables focused, short course, high dose per fraction radiation delivery to brain tumors that are less ideal for single fraction treatment because of size, shape, or close proximity to sensitive structure
Externí odkaz:
https://doaj.org/article/9282942d23054544aa1b68624c08ae9a
Autor:
Anurag Saraf, Torunn I Yock, Andrzej Niemierko, Kevin S Oh, William T Curry, William E Butler, Deborah A Forst, Isabel Arrillaga-Romany, David H Ebb, Nancy J Tarbell, Shannon MacDonald, Jay S Loeffler, Helen A Shih
Publikováno v:
Neuro Oncol
Background Medulloblastoma (MB) is a rare central nervous system malignancy of adults, with limited contemporary studies to define treatment guidelines and expected late toxicity. Methods A single-center, retrospective study was conducted of patients
Autor:
Christina I. Tsien, Stephanie L. Pugh, Adam P. Dicker, Jeffrey J. Raizer, Martha M. Matuszak, Enrico C. Lallana, Jiayi Huang, Ozer Algan, Nimisha Deb, Lorraine Portelance, John L. Villano, John T. Hamm, Kevin S. Oh, Arif N. Ali, Michelle M. Kim, Scott M. Lindhorst, Minesh P. Mehta
PURPOSE To assess whether reirradiation (re-RT) and concurrent bevacizumab (BEV) improve overall survival (OS) and/or progression-free survival (PFS), compared with BEV alone in recurrent glioblastoma (GBM). The primary objective was OS, and secondar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a4c03b0f137d718334db45ae38b7cb4
https://www.zora.uzh.ch/id/eprint/228975/
https://www.zora.uzh.ch/id/eprint/228975/
Autor:
Andrew J. Schoenfeld, Ganesh M. Shankar, John H. Shin, Joseph H. Schwab, Kevin S. Oh, Philip J. Saylor, Ali Kiapour, Muhamed Hadzipasic, Elie Massaad
Publikováno v:
Journal of Neurosurgery: Spine. 35:356-365
OBJECTIVE The effectiveness of starting systemic therapies after surgery for spinal metastases from renal cell carcinoma (RCC) has not been evaluated in randomized controlled trials. Agents that target tyrosine kinases, mammalian target of rapamycin
Autor:
Anita Giobbie-Hurder, Tracy T. Batchelor, Maura Mahar, Michael White, Daniel P. Cahill, Rebecca S. Heist, Justine V. Cohen, Justin F. Gainor, Helen A. Shih, Priscilla K. Brastianos, Scott L. Carter, Ryan J. Sullivan, Deborah Forst, Donald P. Lawrence, Nancy Wang, David P. Ryan, Kevin S. Oh, Sandro Santagata, A. John Iafrate, Albert E. Kim, Jennifer A. Ligibel, Ugonma Chukwueke, Elizabeth R. Gerstner, Eudocia Q. Lee
Publikováno v:
Nature Cancer. 2:498-502
Recent studies suggest that the cyclin-dependent kinase (CDK) pathway may be a therapeutic target for brain metastases (BM). Here, we present interim analysis of a basket trial evaluating the intracranial efficacy of the CDK inhibitor palbociclib in
Autor:
Nayan Lamba, Helen A. Shih, Grace M. Lee, Daniel Kim, Andrzej Niemierko, Robert L. Martuza, Fred G. Barker, Jay S. Loeffler, Paul H. Chapman, Kevin S. Oh, William T. Curry
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 109:252-266
PURPOSE The optimal timing of adjuvant radiation therapy (RT) in the management of atypical meningiomas remains controversial. We compared the outcomes of atypical meningiomas managed with upfront adjuvant RT versus postoperative surveillance. METHOD
Autor:
Ganesh M. Shankar, Nida Fatima, Elie Massaad, Ali Kiapour, John H. Shin, Joseph H. Schwab, Philip J. Saylor, Muhamed Hadzipasic, Kevin S. Oh, Christopher Alvarez-Breckenridge, Andrew J. Schoenfeld
Publikováno v:
Journal of Neurosurgery: Spine. 33:529-539
OBJECTIVEAlthough several prognostic scores for spinal metastatic disease have been developed in the past 2 decades, the applicability and validity of these models to specific cancer types are not yet clear. Most of the data used for model formation
Single-arm, open-label phase 2 trial of pembrolizumab in patients with leptomeningeal carcinomatosis
Autor:
Daniel P. Cahill, Scott L. Carter, Nan Lin, Brian V. Nahed, Jorg Dietrich, Ugonma Chukwueke, Ian E. Krop, Christopher Alvarez-Breckenridge, Nancy Wang, Anita Giobbie-Hurder, Maura Mahar, Beverly Moy, Priscilla K. Brastianos, Justine V. Cohen, Mia Bertalan, Deborah Forst, Michael White, Tracy T. Batchelor, Sara M. Tolaney, Brian A. Shaw, Donald P. Lawrence, Lakshmi Nayak, Helen A. Shih, Kevin S. Oh, Nathaniel Goss, Naema Nayyar, Albert H. Kim, Ryan J. Sullivan, Elizabeth R. Gerstner, Megha Subramanian, Joana L. Mora, Eudocia Q. Lee
Publikováno v:
Nature Medicine. 26:1280-1284
An increasing fraction of patients with metastatic cancer develop leptomeningeal dissemination of disease (LMD), and survival is dismal1–3. We conducted a single-arm, phase 2 study of pembrolizumab in patients with solid tumor malignancies and LMD
Autor:
Stephen Zieminski, Helen A. Shih, William A. Mehan, Henning Willers, Yi Wang, Emily S. Lebow, Melin J. Khandekar, William L. Hwang, Kevin S. Oh, Andrzej Niemierko
Publikováno v:
Journal of Neuro-Oncology. 148:81-88
Cranial irradiation results in cognitive decline, which is hypothesized to be partially attributable to hippocampal injury and stem cell loss. Recent advances allow for targeted reduction of radiation dose to the hippocampi while maintaining adequate