Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kevin S Katen"'
Autor:
Kevin S Katen, John A. Cidlowski, Christine M. Jewell, Crystal Cannon, Lisa M. Barber, Stavros Garantziotis
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 311:E741-E748
The glucocorticoid receptor single-nucleotide polymorphism (SNP) N363S has been reported to be associated with metabolic syndrome, type 2 diabetes, and cardiovascular disease. Our aim was to determine how the N363S SNP modifies glucocorticoid recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c7ec6d3d36c7b1d5b8b6510735e54e6
https://doi.org/10.1152/ajpendo.00105.2016
https://doi.org/10.1152/ajpendo.00105.2016
Autor:
Christine M. Jewell, Kevin S Katen, Wei Yue, Daniel F. Heitjan, Hershel Raff, Richard J. Santen, John A. Cidlowski
Background The glucocorticoid receptor (GR) consists of two alternatively spliced isoforms: GRα, which activates gene transcription, and GRβ, a dominant-negative receptor. Theoretically, inactivating variants of GRβ could result in glucocorticoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f145863c1a62d1e828ae577d215600a
https://europepmc.org/articles/PMC6179182/
https://europepmc.org/articles/PMC6179182/
Autor:
Shannon Whirledge, Lisa M. Barber, John A. Cidlowski, Xiaojiang Xu, Christine M. Jewell, Kevin S Katen, Stavros Garantziotis
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 97(11)
Alternative splicing of the human glucocorticoid receptor gene generates two isoforms, hGRα and hGRβ. hGRβ functions as a dominant-negative regulator of hGRα activity and but also has inherent transcriptional activity, collectively altering gluco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::517b5bcad562a235983bf5c0af853058
https://pubmed.ncbi.nlm.nih.gov/28759007
https://pubmed.ncbi.nlm.nih.gov/28759007
Autor:
Jeffrey D. Chulay, Sarah Negri, John N. Morris, Aubrey D Watson, Kevin S Katen, David I. Bernstein, Pamela Norberg, Kaitlin M Smith, Amy Hoeper, Robert A. Olmsted, Maureen F. Maughan, Elizabeth A. Reap
Publikováno v:
Vaccine. 28:484-493
Development of a cytomegalovirus (CMV) vaccine is a priority. We evaluated a two component alphavirus replicon particle vaccine expressing CMV gB or a pp65/IE1 fusion protein, previously shown to induce robust antibody and cellular immune responses i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6a5651b5e4293f51f135656f5d4f1e9
https://doi.org/10.1016/j.vaccine.2009.09.135
https://doi.org/10.1016/j.vaccine.2009.09.135
Autor:
Nancy C. Behforouz, Aiqin Wang, Wen Cai, Kevin S. Katen, Daniel Briere, Mark G. Stocksdale, Mohammad Behforouz, Joo Yong Jung, Jennifer S. Lucas
Publikováno v:
Journal of Medicinal Chemistry. 46:5773-5780
Novel lavendamycins including two water soluble derivatives were synthesized via short and efficient methods. Pictet-Spengler condensation of 7-N-acylamino-2-formylquinoline-5,8-diones with tryptophans produced lavendamycin esters or amides 11-17. La
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a814ac2ca9de06f09b08854383dfba96
https://doi.org/10.1021/jm0304414
https://doi.org/10.1021/jm0304414
Autor:
Elizabeth A Reap, Kevin S Katen, Aubrey D Watson, Kaitlin M Smith, Pamela K Norberg, Jeffrey D Chulay, Robert A Olmsted
Publikováno v:
The Journal of Immunology. 182:132.14-132.14
We recently completed a Phase I evaluation of a bivalent, virus-like replicon particle (VRP) vaccine (AVX601) expressing three CMV proteins in CMV seronegative adults. One VRP component expressed the pp65 and IE1 genes as a polyprotein and the second
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fc0d82447c3ec5c576b6904c4ac7ece
https://doi.org/10.4049/jimmunol.182.supp.132.14
https://doi.org/10.4049/jimmunol.182.supp.132.14