Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Kevin S Johnson"'
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171406 (2017)
Infection of human cells with Yersinia pseudotuberculosis expressing a functional type III secretion system (T3SS) leads to activation of host NF-κB. We show that the Yersinia T3SS activates distinct NF-κB pathways dependent upon bacterial subcellu
Externí odkaz:
https://doaj.org/article/989e23cf033a4f0dae2187fc3de56355
Autor:
Kevin S. Johnson, Bassam A. Elgamoudi, Freda E.-C. Jen, Christopher J. Day, Emily Goers Sweeney, Megan L. Pryce, Karen Guillemin, Thomas Haselhorst, Victoria Korolik, Karen M. Ottemann
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
ABSTRACT The Helicobacter pylori chemoreceptor TlpA plays a role in dampening host inflammation during chronic stomach colonization. TlpA has a periplasmic dCache_1 domain, a structure that is capable of sensing many ligands; however, the only charac
Externí odkaz:
https://doaj.org/article/958587dd065b4f2d967bac45ac018790
Autor:
Mayra A. Machuca, Kevin S. Johnson, Yu C. Liu, David L. Steer, Karen M. Ottemann, Anna Roujeinikova
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract It is recently appreciated that many bacterial chemoreceptors have ligand-binding domains (LBD) of the dCACHE family, a structure with two PAS-like subdomains, one membrane-proximal and the other membrane-distal. Previous studies had implica
Externí odkaz:
https://doaj.org/article/70d3bd8e624444ddaa9c81528f895161
Autor:
Kevin S. Johnson, Christina Yang, J. Elliot Carter, Atesh K. Worthington, Elektra K. Robinson, Raymond Lopez-Magaña, Frida Salgado, Isabelle Arnold, Karen M. Ottemann
Publikováno v:
Infection and Immunity. 91
Helicobacter pylori colonizes half of the world’s population and is responsible for a significant disease burden by causing gastritis, peptic ulcers, and gastric cancer. The development of host inflammation drives these diseases, but there are stil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::590889296a1f52887e2d82805efd6864
https://doi.org/10.1128/iai.00322-22
https://doi.org/10.1128/iai.00322-22
Autor:
Kevin S, Johnson, Christina, Yang, J Elliot, Carter, Atesh K, Worthington, Elektra K, Robinson, Raymond, Lopez-Magaña, Frida, Salgado, Isabelle, Arnold, Karen M, Ottemann
Publikováno v:
Infect Immun
Helicobacter pylori colonizes half of the world’s population and is responsible for a significant disease burden by causing gastritis, peptic ulcers, and gastric cancer. The development of host inflammation drives these diseases, but there are stil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::315a4e71d0b61261aebcdbc7027378a5
https://pubmed.ncbi.nlm.nih.gov/36533917
https://pubmed.ncbi.nlm.nih.gov/36533917
Autor:
Jessica M. Morgan, Miles C. Duncan, Kevin S. Johnson, Andreas Diepold, Hanh Lam, Allison J. Dupzyk, Lexi R. Martin, Weng Ruh Wong, Judith P. Armitage, Roger G. Linington, Victoria Auerbuch
Publikováno v:
mSphere, Vol 2, Iss 1 (2017)
ABSTRACT The type III secretion system (T3SS) is a bacterial virulence factor expressed by dozens of Gram-negative pathogens but largely absent from commensals. The T3SS is an attractive target for antimicrobial agents that may disarm pathogenic bact
Externí odkaz:
https://doaj.org/article/74f6ceb0df4a419da1d4d7f0ac24f76e
Autor:
Kevin S. Johnson, Christina Yang, J. Elliot Carter, Atesh K. Worthington, Elektra K. Robinson, Raymond Lopez-Magaña, Frida Salgado, Isabelle Arnold, Karen M. Ottemann
Helicobacter pylori colonizes half of the world’s population and is responsible for a significant disease burden by causing gastritis, peptic ulcers, and gastric cancer. The development of host inflammation drives these diseases, but there are stil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99866435ad131dff802840ecbbdc1dad
https://doi.org/10.1101/2022.08.01.502425
https://doi.org/10.1101/2022.08.01.502425
Autor:
Freda E.-C. Jen, Megan L. Pryce, Karen Guillemin, Thomas Haselhorst, Kevin S. Johnson, Christopher J. Day, Karen M. Ottemann, Emily Goers Sweeney, Bassam A. Elgamoudi, Victoria Korolik
Publikováno v:
mBio, Vol 12, Iss 4 (2021)
mBio
mBio, vol 12, iss 4
mBio
mBio, vol 12, iss 4
The Helicobacter pylori chemoreceptor TlpA plays a role in dampening host inflammation during chronic stomach colonization. TlpA has a periplasmic dCache_1 domain, a structure that is capable of sensing many ligands; however, the only characterized T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef564a708d1949d6cd764f27861fdebc
https://journals.asm.org/doi/10.1128/mBio.01819-21
https://journals.asm.org/doi/10.1128/mBio.01819-21
Autor:
Karen Guillemin, Pryce Ml, Karen M. Ottemann, Emily Goers Sweeney, Korolik, Thomas Haselhorst, Kevin S. Johnson, Freda E.-C. Jen, Christopher J. Day, Bassam A. Elgamoudi
The Helicobacter pylori chemoreceptor TlpA plays a role in dampening host inflammation during chronic stomach colonization. TlpA has a periplasmic dCache_1 domain, a structure that is capable of sensing many ligands; however, the only characterized T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0669965da0d50ef9d8fcc1fce82e25e7
https://doi.org/10.1101/2021.04.07.438267
https://doi.org/10.1101/2021.04.07.438267
Publikováno v:
mAbs
Monoclonal anti-programmed cell death 1 (PD1) antibodies are successful cancer therapeutics, but it is not well understood why individual antibodies should have idiosyncratic side-effects. As the humanized antibody SHR-1210 causes capillary hemangiom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d133e4e442a49d292489c35ab57695a
https://doi.org/10.1080/19420862.2018.1550321
https://doi.org/10.1080/19420862.2018.1550321