Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kevin R. Schwarzkopf"'
Autor:
Kevin R. Schwarzkopf, Dean Messing, Maria W. Smith, Ibrahim Sezan, Andrey L. Ghindilis, David R. Evans, Holly M. Simon, Changqing Zhan, Paul J. Schuele
Publikováno v:
ECS Transactions. 33:59-68
An impedimetric biosensor platform for bioaffinity assays has been developed that is based on real-time, label-free electrochemical detection performed via a direct interface to electronic digital data processing. The sensor array consists of 15 gold
Autor:
Maria W. Smith, David R. Evans, Andrei L. Ghindilis, Kevin R. Schwarzkopf, António M. Baptista, Holly M. Simon, Changqing Zhan
Publikováno v:
Electroanalysis. 21:1459-1468
A novel, impedance-based electronic sensor format was used for label-free, real-time detection of microbial DNA on oligonucleotide probe arrays. Detection limits of 5–10 nM were achieved for single-stranded, PCR-amplified DNA targets. Hybridization
Autor:
Karen Bernards, Axel G. Stöver, Kevin R. Schwarzkopf, Kristian M. Roth, Andy McShea, Sandra B. Munro, Michael J. Lodes, Kia Peyvan, Maria W. Smith, Kilian Dill, Andrey L. Ghindilis
Publikováno v:
Biosensors and Bioelectronics. 22:1853-1860
Electrochemical detection has been developed and assay performances studied for the CombiMatrix oligonucleotide microarray platform that contains 12,544 individually addressable microelectrodes (features) in a semiconductor matrix. The approach is ba
Publikováno v:
Electroanalysis. 18:1982-1988
A microarray reader named ElectraSense using an electrochemical detection technique has been developed for the CombiMatrix CustomArray 12 544 electrode semiconductor DNA microarray. The detection is based on electrochemical reduction of the enzymatic
Autor:
Robin Hui Liu, Kevin R. Schwarzkopf, Michael Bizak, Alla Petrova, H. Sho Fuji, Andy McShea, Tony Siuda, Tai Nguyen, Kia Peyvan, David Danley
Publikováno v:
Analytical Chemistry. 78:1980-1986
A DNA microarray with 12,000 features was integrated with a microfluidic cartridge to automate the fluidic handling steps required to carry out a gene expression study of the human leukemia cell line (K562). The fully integrated microfluidic device c
Autor:
Carmen E. Campbell, David R. Evans, Ibrahim Sezan, Vena N. Haynes, George B. Middleton, Holly M. Simon, Dean Messing, Maria W. Smith, Kevin R. Schwarzkopf, Changqing Zhan, Andrei L. Ghindilis, John W. Hartzell, Bruce D. Ulrich, Paul J. Schuele, Michael J. Frasier
Publikováno v:
Biosensorsbioelectronics. 35(1)
A real-time, label free assay was developed for microbial detection, utilizing double-stranded DNA targets and employing the next generation of an impedimetric sensor array platform designed by Sharp Laboratories of America (SLA). Real-time curves of
Publikováno v:
EMBC
Scopus-Elsevier
Scopus-Elsevier
In previously published work [1] we presented a real-time electrochemical impedance biosensor prototype system and a state-space estimation algorithm for signal quantification. Experiments in the interim have revealed some algorithm failure modes whi
Publikováno v:
Scopus-Elsevier
We describe our real-time, label-free, electrochemical impedance biosensor system with an emphasis on the use of an impedance response signal model to quantify assays. The signal processing for estimating model parameters from noisy data and the quan
Publikováno v:
Immunoassay and Other Bioanalytical Techniques
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dd7b168a961f4e9d1ed7c398a84eea2
https://doi.org/10.1201/9781420020694.ch19
https://doi.org/10.1201/9781420020694.ch19
Autor:
S.R. Ragsdale, Andrey L. Ghindilis, Kilian Dill, Donald D. Montgomery, Andrew V. Oleinikov, Kevin R. Schwarzkopf
Publikováno v:
Biosensorsbioelectronics. 20(4)
We show that CombiMatrix’s VLSI arrays of individually addressable electrodes, using conventional CMOS integrated circuitry, can be used in detecting various analytes via immunoassay protocols. These microarrays provide over 1000 electrodes per squ