Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kevin R. Munro"'
Autor:
Cinta Diez-Ardanuy, Jennifer Greaves, Kevin R. Munro, Nicholas C. O. Tomkinson, Luke H. Chamberlain
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Autosomal-dominant adult-onset neuronal ceroid lipofuscinosis (ANCL) is caused by mutation of the DNAJC5 gene encoding cysteine string protein alpha (CSPα). The disease-causing mutations, which result in substitution of leucine-115 with an
Externí odkaz:
https://doaj.org/article/2a20638872464157949edca61f2db773
Autor:
Christine Salaun, Hiroya Takizawa, Alex Galindo, Kevin R. Munro, Jayde McLellan, Isamu Sugimoto, Tomotaka Okino, Nicholas C.O. Tomkinson, Luke H. Chamberlain
Publikováno v:
The Journal of biological chemistry. 298(10)
Protein S-acylation is a reversible post-translational modification that modulates the localization and function of many cellular proteins. S-acylation is mediated by a family of zinc finger DHHC (Asp-His-His-Cys) domain-containing (zDHHC) proteins e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b96c3029461796d879bea82b6e06ec
https://pubmed.ncbi.nlm.nih.gov/36087837
https://pubmed.ncbi.nlm.nih.gov/36087837
Autor:
Kevin R. Munro, Cinta Diez-Ardanuy, Luke H. Chamberlain, Jennifer Greaves, Nicholas C. O. Tomkinson
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports
Scientific Reports
Autosomal-dominant adult-onset neuronal ceroid lipofuscinosis (ANCL) is caused by mutation of the DNAJC5 gene encoding cysteine string protein alpha (CSPα). The disease-causing mutations, which result in substitution of leucine-115 with an arginine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d955c3029a31277bc4391816814688cb
https://doaj.org/article/2a20638872464157949edca61f2db773
https://doaj.org/article/2a20638872464157949edca61f2db773
Autor:
Kevin R. Munro, Richard S. Grainger
Publikováno v:
Tetrahedron. 71(41):7795-7835
Alkylidene carbenes, also called alkenylidenes, are reactive intermediates in organic chemistry. Despite their high reactivity, they undergo a range of synthetically useful transformations, including highly chemoand regioselective intramolecular 1,5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e141c70b0fe24acb2649176a3442a33b
Autor:
Kevin R. Munro, Nicholas C. O. Tomkinson, Luke H. Chamberlain, Matthieu Riviere, Terry K. Smith, Jennifer Greaves, Justyna Wojno, Stuart C. Davidson
This work was funded by Biotechnology and Biological Sciences Research Council Grant BB/L022087/1 (to T.K.S., N.C.O.T., and L.H.C.) and Wellcome Trust Grant 093228 (to T.K.S.). S-acylation is a major posttranslational modification, catalyzed by the z
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6d7d0c815805dc66f4895c2770014f
https://hdl.handle.net/10023/11394
https://hdl.handle.net/10023/11394
Autor:
Kevin R. Munro, Richard S. Grainger
Publikováno v:
ChemInform. 46
Alkylidene carbenes, also called alkenylidenes, are reactive intermediates in organic chemistry. Despite their high reactivity, they undergo a range of synthetically useful transformations, including highly chemoand regioselective intramolecular 1,5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3f3903d03258d98e17374789208d619
https://doi.org/10.1002/chin.201545243
https://doi.org/10.1002/chin.201545243
Publikováno v:
Organic & Biomolecular Chemistry. 11:6856
α-Hydroxyalkylidene carbenes, generated from thermolysis of α,β-epoxy-N-aziridinylimines, undergo diastereotopic group selective 1,5 C–H insertion reactions on 2,4-dimethyl-8-oxabicyclo[3.2.1]oct-6-ene ring systems. Protection of a tertiary alco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaaf1b8f87d8aa661f37810d47d7a710
https://doi.org/10.1039/c3ob41390j
https://doi.org/10.1039/c3ob41390j