Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Kevin R. Clark"'
Autor:
Elena Ferri, Adrien Le Thomas, Heidi Ackerly Wallweber, Eric S. Day, Benjamin T. Walters, Susan E. Kaufman, Marie-Gabrielle Braun, Kevin R. Clark, Maureen H. Beresini, Kyle Mortara, Yung-Chia A. Chen, Breanna Canter, Wilson Phung, Peter S. Liu, Alfred Lammens, Avi Ashkenazi, Joachim Rudolph, Weiru Wang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The RNase activity of Inositol-Requiring Enzyme 1 (IRE1) can be allosterically regulated by ATP-competitive inhibitors of the IRE1 kinase domain. Here, the authors identify ATP-competitive IRE1 RNase activators with improved selectivity and cellular
Externí odkaz:
https://doaj.org/article/b949b998bea04b119070c87d6eced201
Autor:
Kevin R. Clark
Publikováno v:
Journal of Educators Online, Vol 12, Iss 1 (2015)
In many of the secondary classrooms across the country, students are passively engaged in the mathematics content, and academic performance can be described, at best, as mediocre. This research study sought to bring about improvements in student enga
Externí odkaz:
https://doaj.org/article/a945579d6b764955876157c1b73ec1b5
Autor:
Isaac D. Valdez, Catherine E. Ramirez, Armin Khansari, Ilam Momin, Chase Sitzmann, Mahsa Dehghanpour, Kevin R. Clark
Publikováno v:
Medical Dosimetry.
Autor:
Kevin R, Clark
Publikováno v:
Radiologic technology. 94(1)
Autor:
Breanna Canter, Benjamin T. Walters, Alfred Lammens, Peter Liu, Avi Ashkenazi, Wilson Phung, Weiru Wang, Kevin R Clark, Adrien Le Thomas, Joachim Rudolph, Heidi J.A. Wallweber, Elena Ferri, Eric S. Day, Kyle Mortara, Maureen Beresini, Marie-Gabrielle Braun, Yung-Chia A. Chen, Susan Kaufman
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications
Inositol-Requiring Enzyme 1 (IRE1) is an essential component of the Unfolded Protein Response. IRE1 spans the endoplasmic reticulum membrane, comprising a sensory lumenal domain, and tandem kinase and endoribonuclease (RNase) cytoplasmic domains. Exc
Autor:
Kevin R, Clark
Publikováno v:
Radiologic technology. 92(3)
Autor:
Kevin R, Clark
Publikováno v:
Radiologic technology. 92(2)
Autor:
Sanjay Srivastava, Susan Kaufman, Joachim Rudolph, Ghiro Elise, Heidi J.A. Wallweber, Jean-Philippe Leclerc, Beveridge Ramsay, Liang Zhao, Marie-Gabrielle Braun, Lemire Alexandre, Mélissa Leblanc, Alexandre Larivée, Cuong Ly, Weiru Wang, Avi Ashkenazi, Maureen Beresini, Jacob Schwarz, Paul Gibbons, Kevin R Clark
Publikováno v:
ACS Med Chem Lett
[Image: see text] Amino-quinazoline BRaf kinase inhibitor 2 was identified from a library screen as a modest inhibitor of the unfolded protein response (UPR) regulating potential anticancer target IRE1α. A combination of crystallographic and conform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::082aa3dbc959d40a4b3123339657e04c
https://europepmc.org/articles/PMC7734639/
https://europepmc.org/articles/PMC7734639/
Autor:
Lindi L, Boyd, Kevin R, Clark
Publikováno v:
Radiologic technology. 93(2)
To determine whether radiologic technologists are manipulating projections to lower patient dose in routine pediatric radiography examinations.Using a descriptive survey approach, members from the American Society of Radiologic Technologists with a p
Autor:
Tammy L, Webster, Kevin R, Clark
Publikováno v:
Radiologic technology. 92(2)
To examine radiologic science programs' mitigation activities and educators' experiences related to coronavirus disease 2019 (COVID-19) response planning.Using a mixed-methods approach, educators in magnetic resonance, medical dosimetry, radiation th