Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Kevin R, Parker"'
Publikováno v:
International Journal of Educational Technology in Higher Education, Vol 19, Iss 1, Pp 1-21 (2022)
Abstract While various studies have focused on the significance of computational thinking (CT) for the future career paths of individuals in science, technology, engineering, and mathematics (STEM), few studies have focused on computational thinking
Externí odkaz:
https://doaj.org/article/13e819d16ba9482a86209e0295f71450
Autor:
Joshua R Wheeler, Oscar N Whitney, Thomas O Vogler, Eric D Nguyen, Bradley Pawlikowski, Evan Lester, Alicia Cutler, Tiffany Elston, Nicole Dalla Betta, Kevin R Parker, Kathryn E Yost, Hannes Vogel, Thomas A Rando, Howard Y Chang, Aaron M Johnson, Roy Parker, Bradley B Olwin
Publikováno v:
eLife, Vol 11 (2022)
RNA-binding proteins (RBPs), essential for skeletal muscle regeneration, cause muscle degeneration and neuromuscular disease when mutated. Why mutations in these ubiquitously expressed RBPs orchestrate complex tissue regeneration and direct cell fate
Externí odkaz:
https://doaj.org/article/4b073abee28f4aae9ef7aac8ebbbed02
Autor:
Crystal L. Mackall, Ravindra Majeti, Robbie G. Majzner, Ansuman T. Satpathy, Howard Y. Chang, Poul H. Sorensen, Wan-Jen Hong, Jie Liu, Htoo Zarni Oo, Mads Daugaard, Elena Sotillo, Amy Fan, Peng Xu, Kevin R. Parker, Katherine A. Freitas, Feifei Zhao, Rebecca M. Richards
Supplemental figures and legends in one document
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a648a9aba5801dbaef9a405c3d987d75
https://doi.org/10.1158/2643-3230.22543087
https://doi.org/10.1158/2643-3230.22543087
Autor:
Arun P. Wiita, Elliot Stieglitz, Aashish Manglik, Ansuman T. Satpathy, Byron C. Hann, Faranak Fattahi, Veronica Steri, Paul Phojanokong, Anne Deucher, Jonathan Ramirez, Kevin R. Parker, Sagar P. Bapat, Jeffrey D. Whitman, Kristie L. White, Makeba Marcoulis, Jose M. Rivera, Yu-Hsiu T. Lin, Neha Paranjape, Huimin Geng, Kamal Mandal, Matthew A. Nix
Alternative strategies are needed for patients with B-cell malignancy relapsing after CD19-targeted immunotherapy. Here, cell surface proteomics revealed CD72 as an optimal target for poor-prognosis KMT2A/MLL1-rearranged (MLLr) B-cell acute lymphobla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4eda55a5274e3677f255a2fad22066d9
https://doi.org/10.1158/2159-8290.c.6548995.v1
https://doi.org/10.1158/2159-8290.c.6548995.v1
Autor:
Arun P. Wiita, Elliot Stieglitz, Aashish Manglik, Ansuman T. Satpathy, Byron C. Hann, Faranak Fattahi, Veronica Steri, Paul Phojanokong, Anne Deucher, Jonathan Ramirez, Kevin R. Parker, Sagar P. Bapat, Jeffrey D. Whitman, Kristie L. White, Makeba Marcoulis, Jose M. Rivera, Yu-Hsiu T. Lin, Neha Paranjape, Huimin Geng, Kamal Mandal, Matthew A. Nix
Supplementary Data from Surface Proteomics Reveals CD72 as a Target for In Vitro–Evolved Nanobody-Based CAR-T Cells in KMT2A/MLL1-Rearranged B-ALL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::071cd4a9ceee3e0f3be7d0956260a267
https://doi.org/10.1158/2159-8290.22539136.v1
https://doi.org/10.1158/2159-8290.22539136.v1
Autor:
Arun P. Wiita, Elliot Stieglitz, Aashish Manglik, Ansuman T. Satpathy, Byron C. Hann, Faranak Fattahi, Veronica Steri, Paul Phojanokong, Anne Deucher, Jonathan Ramirez, Kevin R. Parker, Sagar P. Bapat, Jeffrey D. Whitman, Kristie L. White, Makeba Marcoulis, Jose M. Rivera, Yu-Hsiu T. Lin, Neha Paranjape, Huimin Geng, Kamal Mandal, Matthew A. Nix
Supplementary Figure from Surface Proteomics Reveals CD72 as a Target for In Vitro–Evolved Nanobody-Based CAR-T Cells in KMT2A/MLL1-Rearranged B-ALL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d17db5e546d5631791798d1c469ce4
https://doi.org/10.1158/2159-8290.22539127
https://doi.org/10.1158/2159-8290.22539127
Autor:
Connor A. Tsuchida, Nadav Brandes, Raymund Bueno, Marena Trinidad, Thomas Mazumder, Bingfei Yu, Byungjin Hwang, Christopher Chang, Jamin Liu, Yang Sun, Caitlin R. Hopkins, Kevin R. Parker, Yanyan Qi, Ansuman T. Satpathy, Edward A. Stadtmauer, Jamie H.D. Cate, Justin Eyquem, Joseph A. Fraietta, Carl H. June, Howard Y. Chang, Chun Jimmie Ye, Jennifer A. Doudna
Publikováno v:
bioRxiv
SummaryCRISPR-Cas9 genome editing has enabled advanced T cell therapies, but occasional loss of the targeted chromosome remains a safety concern. To investigate whether Cas9-induced chromosome loss is a universal phenomenon and evaluate its clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0baf40bba37165f6e745af572aee8d6a
https://doi.org/10.1101/2023.03.22.533709
https://doi.org/10.1101/2023.03.22.533709
Publikováno v:
Cancer Cell. 39:1553-1557
The remarkable specificity of antibodies has enabled precision cancer immunotherapies, including chimeric antigen receptor T cells and antibody-drug conjugates. In parallel, single-cell genomics technologies present the possibility of a comprehensive
CRISPR perturbations are valuable tools for studying the functional effects of the genome. However, existing methods are limited in their utility for studying noncoding elements and genetic interactions. Here, we develop a system for bidirectional ep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cdeb6e901d8fac43f364bc325fdd101
https://doi.org/10.1101/2022.11.15.516658
https://doi.org/10.1101/2022.11.15.516658
Publikováno v:
PLoS Genetics, Vol 13, Iss 12, p e1007114 (2017)
ciRS-7 is an intensely studied, highly expressed and conserved circRNA. Essentially nothing is known about its biogenesis, including the location of its promoter. A prevailing assumption has been that ciRS-7 is an exceptional circRNA because it is tr
Externí odkaz:
https://doaj.org/article/966a06f715b64cf494caf35a7a9d5727