Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kevin Peasley"'
Publikováno v:
Pediatric Nephrology (Berlin, Germany)
Acute kidney injury (AKI) is an extremely common medical affliction affecting both adult and pediatric patients resulting from hypoxic, nephrotoxic, and septic insults affecting approximately 20% of all hospital patients and up to 50% of patients in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f2843729257d0664ce6ce1b8d7e11c
https://doi.org/10.1007/s00467-020-04866-z
https://doi.org/10.1007/s00467-020-04866-z
Autor:
Sivakama S. Bharathi, Yuxun Zhang, Takuto Chiba, Nathan Basisty, Eric S. Goetzman, Sunder Sims-Lucas, Kasey R Cargill, Kevin Peasley, Elina Mukherjee, Anja Holtz, Katherine Maringer, Birgit Schilling, Shiva D Yagobian
Publikováno v:
J Am Soc Nephrol
BACKGROUND: The primary site of damage during AKI, proximal tubular epithelial cells, are highly metabolically active, relying on fatty acids to meet their energy demands. These cells are rich in mitochondria and peroxisomes, the two organelles that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3598e421ee3dff3a85a636fd98a1e9ee
https://doi.org/10.1681/asn.2019020163
https://doi.org/10.1681/asn.2019020163
Autor:
Sunder Sims-Lucas, Satdarshan P.S. Monga, Sivakama S. Bharathi, Steven F. Dobrowolski, Eric S. Goetzman, Yuxun Zhang, Xue-Jun Zhao, Kevin Peasley
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Medium-chain triglycerides (MCT), containing C8–C12 fatty acids, are used to treat several pediatric disorders and are widely consumed as a nutritional supplement. Here, we investigated the role of the sirtuin deacylase Sirt5 in MCT metabolism by f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90bcc019e72e23a1f6206b29f2d67c6
http://europepmc.org/articles/PMC7591893
http://europepmc.org/articles/PMC7591893