Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kevin P. Webster"'
Publikováno v:
Palliative Medicine Reports, Vol 2, Iss 1, Pp 340-348 (2021)
Background: Emergency departments (ED) and other medical points of care are required to provide patients with advance directive (AD) information. Although many hospitals provide AD information in EDs, the comfort and preparation of the ED staff with
Externí odkaz:
https://doaj.org/article/acca3d00cc2b44839c96c76c0e8a03e3
Autor:
Kevin D. Webster, Arndt Schimmelmann, Agnieszka Drobniak, Maria Mastalerz, Laura Rosales Lagarde, Penelope J. Boston, Jay T. Lennon
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 4 (2022)
ABSTRACT Methane oxidizing microorganisms (methanotrophs) are ubiquitous in the environment and represent a major sink for the greenhouse gas methane (CH4). Recent studies have demonstrated methanotrophs are abundant and contribute to CH4 dynamics in
Externí odkaz:
https://doaj.org/article/5323584d8e0d4fec841e9428831e120e
Autor:
Adina Gerson-Gurwitz, Nathan P. Young, Vikas K. Goel, Boreth Eam, Craig R. Stumpf, Joan Chen, Sarah Fish, Maria Barrera, Eric Sung, Jocelyn Staunton, Gary G. Chiang, Kevin R. Webster, Peggy A. Thompson
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Oncoprotein expression is controlled at the level of mRNA translation and is regulated by the eukaryotic translation initiation factor 4F (eIF4F) complex. eIF4A, a component of eIF4F, catalyzes the unwinding of secondary structure in the 5’-untrans
Externí odkaz:
https://doaj.org/article/3c591166c36f4888bb12e979b6ceb351
Autor:
Sujata Jana, Rucha Deo, Rowan P. Hough, Yuzhen Liu, Jessie L. Horn, Jonathan L. Wright, Hung-Ming Lam, Kevin R. Webster, Gary G. Chiang, Nahum Sonenberg, Andrew C. Hsieh
Publikováno v:
JCI Insight, Vol 6, Iss 11 (2021)
Using genetically engineered mouse models, this work demonstrates that protein synthesis is essential for efficient urothelial cancer formation and growth but dispensable for bladder homeostasis. Through a candidate gene analysis for translation regu
Externí odkaz:
https://doaj.org/article/2f23ca10819f4654a2a0748a88d95c63
Autor:
Martilias S Farrell, John D McCorvy, Xi-Ping Huang, Daniel J Urban, Kate L White, Patrick M Giguere, Allison K Doak, Alison I Bernstein, Kristen A Stout, Su Mi Park, Ramona M Rodriguiz, Bradley W Gray, William S Hyatt, Andrew P Norwood, Kevin A Webster, Brenda M Gannon, Gary W Miller, Joseph H Porter, Brian K Shoichet, William E Fantegrossi, William C Wetsel, Bryan L Roth
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150602 (2016)
RATIONALE:The sacred lotus (Nelumbo nucifera) contains many phytochemicals and has a history of human use. To determine which compounds may be responsible for reported psychotropic effects, we used in silico predictions of the identified phytochemica
Externí odkaz:
https://doaj.org/article/6d67de2b55b746cc9335cb74037f20c1
Autor:
Gautham Venugopalan, David B Camarillo, Kevin D Webster, Clay D Reber, James A Sethian, Valerie M Weaver, Daniel A Fletcher, Hana El-Samad, Chris H Rycroft
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e101955 (2014)
Cell-matrix and cell-cell mechanosensing are important in many cellular processes, particularly for epithelial cells. A crucial question, which remains unexplored, is how the mechanical microenvironment is altered as a result of changes to multicellu
Externí odkaz:
https://doaj.org/article/abe99c7eb82d41b08f12be8f6cc7e5b7
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17807 (2011)
Atomic force microscopy (AFM) has become a powerful tool for measuring material properties in biology and imposing mechanical boundary conditions on samples from single molecules to cells and tissues. Constant force or constant height can be maintain
Externí odkaz:
https://doaj.org/article/d9f473ad2ae04e3b9238d07927c4eeee
Autor:
Robert C. Bast, Susan R. Pilat, Kevin P. Webster, Michael A. Mallamaci, Dwana Sanders, Eileen Babcock, Jill Van Wart Hood, Razelle Kurzrock, Stanley D. Tucker, Steven Strand, Marcel Bartolazzi
Publikováno v:
Journal of Clinical Oncology. 27:4433-4440
Drug development in cancer research is lengthy and expensive. One of the rate-limiting steps is the initiation of first-in-human (phase I) trials. Three to 6 months can elapse between investigational new drug (IND) approval by the US Food and Drug Ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b6bb4007a6e5decb08eac0e7bad6e41
https://doi.org/10.1200/jco.2008.21.6093
https://doi.org/10.1200/jco.2008.21.6093
Autor:
Carolyn Bieber, Michael E. Menefee, Vahab Fatourechi, Anne M. Traynor, Keith C. Bible, Jill K. Burton, Joseph Rubin, Ian D. Hay, Nina J. Karlin, Charles Erlichman, Robert C. Smallridge, Kevin P. Webster, Julian R. Molina, Kostandinos Sideras, Vera J. Suman, William J. Maples, Bryan McIver, Boon Cher Goh, Patrick J. Flynn, Crescent R. Isham, Pamela Jo Harris, John C. Morris
Pazopanib is a small molecule inhibitor of kinases principally including vascular endothelial growth factor receptors-1, -2, and -3; platelet-derived growth factor receptors-α and -β; and c-Kit. We previously reported a tumor response rate of 49% i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f90af02edd6a9671e52efb9a879d4c
https://europepmc.org/articles/PMC4010705/
https://europepmc.org/articles/PMC4010705/
Autor:
Wan-Teck Lim, Andrea K. Kukla, Nina J. Karlin, Julian R. Molina, Keith C. Bible, Vera J. Suman, Robert C. Smallridge, Charles Erlichman, Kevin P. Webster, Boon Cher Goh, Anne M. Traynor, Priya Kumar, Jill K. Burton, Pamela Jo Harris, Carolyn Bieber, Michael E. Menefee, Ayoko R. Bossou, William J. Maples, Crescent R. Isham
Publikováno v:
The Journal of clinical endocrinology and metabolism. 97(9)
Pazopanib, an inhibitor of kinases including vascular endothelial growth factor receptor, demonstrated impressive activity in progressive metastatic differentiated thyroid cancer, prompting its evaluation in anaplastic thyroid cancer (ATC).Preclinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f28f9f3eab8ad4ce5eb62ea4875d0b56
https://pubmed.ncbi.nlm.nih.gov/22847238
https://pubmed.ncbi.nlm.nih.gov/22847238