Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Kevin P Killeen"'
Autor:
Robert T Cartee, Ann Thanawastien, Thomas J Griffin Iv, John J Mekalanos, Stephan Bart, Kevin P Killeen
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 1, p e0007912 (2020)
BACKGROUND:Typhoid fever remains a significant cause of morbidity and mortality in developing countries especially in children ≤5 years old. Although the widely available unconjugated Vi polysaccharide vaccines are efficacious, they confer limited,
Externí odkaz:
https://doaj.org/article/2a50a6751c374121b9263e76863bbf71
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 15, Iss 6, Pp 1310-1316 (2019)
Typhax is an investigational typhoid fever vaccine candidate that was GMP manufactured applying Protein Capsular Matrix Vaccine (PCMV) technology. It consists of Vi polysaccharide antigen, derived from S. Typhi, non-covalently entrapped in a glutaral
Externí odkaz:
https://doaj.org/article/fbfd1a19c87b421c8195c1660aafc381
Autor:
Kevin P. Killeen
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 14, Iss 4, Pp 804-806 (2018)
Externí odkaz:
https://doaj.org/article/0c198b54809f445187755b289485e9ac
Autor:
Rodney K. Tweten, Robert T. Cartee, Laurel A. Haines, Stephen I. Pelton, Ann Thanawastien, Kevin P. Killeen, Kelsey E. Joyce
Publikováno v:
Vaccine
Pneumolysin is a highly conserved, cholesterol-dependent cytolysin that is an important Streptococcus pneumoniae virulence factor and an attractive target for vaccine development. To attenuate pneumolysin toxicity, a genetic toxoid was constructed wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7301ed964fc47b86ee5939bb3b0bd45
http://europepmc.org/articles/PMC8237519
http://europepmc.org/articles/PMC8237519
Autor:
John J. Mekalanos, Kevin P. Killeen, Robert T. Cartee, Thomas J. Griffin, Stephan Bart, Ann Thanawastien
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 1, p e0007912 (2020)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Background Typhoid fever remains a significant cause of morbidity and mortality in developing countries especially in children ≤5 years old. Although the widely available unconjugated Vi polysaccharide vaccines are efficacious, they confer limited,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee109d7f67a1121f7283b7faf43bd700
https://doaj.org/article/2a50a6751c374121b9263e76863bbf71
https://doaj.org/article/2a50a6751c374121b9263e76863bbf71
Publikováno v:
Hum Vaccin Immunother
Typhax is an investigational typhoid fever vaccine candidate that was GMP manufactured applying Protein Capsular Matrix Vaccine (PCMV) technology. It consists of Vi polysaccharide antigen, derived from S. Typhi, non-covalently entrapped in a glutaral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2225f58ad18f522007534cb7c4f5f856
https://pubmed.ncbi.nlm.nih.gov/31021700
https://pubmed.ncbi.nlm.nih.gov/31021700
Autor:
Lawrence J. Thomas, Kevin P. Killeen, Donata R. Sizemore, Elizabeth Warner, Julie A. Lawrence, Kenneth L. Roland
Publikováno v:
Human Vaccines & Immunotherapeutics. 8:371-383
Preclinical studies evaluating plague vaccine candidates have demonstrated that the F1 and V protein antigens of Yersinia pestis confer protection against challenge from virulent strains. Live-attenuated ΔphoP/Q Salmonella typhimurium recombinants w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::154836099f7c43f62adb94ee28c06694
https://doi.org/10.4161/hv.18670
https://doi.org/10.4161/hv.18670
Autor:
Kevin P Killeen
Publikováno v:
Human Vaccines. 5:667-670
The 2009 World Vaccine Congress (WVC) meeting was held in Chantilly, VA from April 20-23. This is a summary of the ‘Adjuvant and Delivery Technologies’ session chaired by Dr. William Warren of VaxDesign. The WVC ‘Adjuvants and Delivery Technolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15b01d25de71a24ffe06a7d4a1ead9f2
https://doi.org/10.4161/hv.5.10.9140
https://doi.org/10.4161/hv.5.10.9140
Autor:
Kenneth L. Roland, Lawrence J. Thomas, Kevin P. Killeen, Steven A. Tinge, Sims K. Kochi, Craig J. Rouskey, Cheryl Cloninger
Publikováno v:
Vaccine. 25:8574-8584
Enterotoxigenic Escherichia coli (ETEC) is the leading cause of traveler's diarrhea. The heat-labile (LT) and heat-stable (ST) toxins mediate ETEC induced diarrhea. ETEC strains may express LT, ST, or both LT and ST, with LT-expressing strains accoun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ad9af219b39cc163167bda0260c0ce
https://doi.org/10.1016/j.vaccine.2007.09.074
https://doi.org/10.1016/j.vaccine.2007.09.074
Capsular polysaccharides are the primary antigenic components involved in protective immunity against encapsulated bacterial pathogens. Although immunization of adolescents and adults with polysaccharide antigens has reduced pathogen disease burden,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::313577a7d8e6b1d59143a7dfe6c093e7
https://europepmc.org/articles/PMC4364189/
https://europepmc.org/articles/PMC4364189/
