Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Kevin Ngo"'
Autor:
Rajesh Ghosh, Hyou-Arm Joung, Artem Goncharov, Barath Palanisamy, Kevin Ngo, Katarina Pejcinovic, Nicole Krockenberger, Elizabeth J. Horn, Omai B. Garner, Ezdehar Ghazal, Andrew O’Kula, Paul M. Arnaboldi, Raymond J. Dattwyler, Aydogan Ozcan, Dino Di Carlo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Point-of-care serological and direct antigen testing offers actionable insights for diagnosing challenging illnesses, empowering distributed health systems. Here, we report a POC-compatible serologic test for Lyme disease (LD), leveraging sy
Externí odkaz:
https://doaj.org/article/5701891b0a5b42b8b0784916838600f0
Autor:
Paul D. Robbins, Kevin Ngo, Qing Dong, Tony Wyss-Coray, Nam Vo, Hongsheng Lin, Prashanti Patil, Debora Colangelo, Joon S. Lee, Laura J. Niedernhofer, Gwendolyn Sowa, Changbin Lei, Matthew J. Yousefzadeh, Vivian Li, Derek M. Huffman, Dong Wang, James M. Kang
Publikováno v:
Aging (Albany NY)
Whether disc aging is influenced by factors beyond its local environment is an important unresolved question. Here we performed heterochronic parabiosis in mice to study the effects of circulating factors in young and old blood on age-associated inte
Autor:
Hyou-Arm Joung, Rajesh Ghosh, Artem Goncharov, Kevin Ngo, Barath Palanisamy, Marcell Veszpremi, Elizabeth J. Horn, Paul M. Arnaboldi, Raymond J. Dattwyler, Omai B. Garner, Dino Di Carlo, Aydogan Ozcan
Publikováno v:
Frontiers in Optics + Laser Science 2022 (FIO, LS).
We report a paper-based multi-peptide optical sensor processed by a neural network for point-of-care testing of Lyme disease. Using clinical serum samples, we demonstrate 91.7% sensitivity and 100% specificity without cross-reactivity with other dise
Publikováno v:
SSRN Electronic Journal.
Autor:
Jitendra D. Belani, Narasimham Ayyagari, Milind M. Ahire, Kevin Ngo, Sunil Kumar Sunnam, Minxi Yang
Publikováno v:
Synlett. 31:87-91
A palladium-catalyzed oxidative C–H allylic alkylation of N-hydroxyimides has been developed. This transformation provided valuable N-allyloxypyrrolidinediones in moderate to excellent yields using operationally simple, ligand free, and mild reacti
Autor:
Nicholas Vaudreuil, Qing Dong, Gwendolyn Sowa, Robert A. Hartman, Tiffany R. Kadow, J. Paulo Coelho, Kevin Ngo, Nam Vo, Pedro Pohl, Takashi Yurube, James D. Kang
Publikováno v:
The Spine Journal. 17:1163-1170
Background Context Non-steroidal anti-inflammatory drugs (NSAIDs) are a widely used treatment for low back pain (LBP). Literature on NSAID use in articular cartilage has shown detrimental effects; however, minimal data exist to detail the effects of
Autor:
Vincenzo Denaro, Gianluca Vadalà, Kevin Ngo, Luca Ambrosio, Gwendolyn Sowa, Nam Vo, Yong Fan, James D. Kang, Fabrizio Russo
Publikováno v:
Spine (Phila Pa 1976)
STUDY DESIGN. An experimental laboratory study. OBJECTIVE. To investigate the pathogenesis of intervertebral disc degeneration (IDD) in a murine model of type 1 diabetes mellitus (DM), namely non-obese diabetic (NOD) mouse. SUMMARY OF BACKGROUND DATA
Autor:
Hong J. Moon, Luciano Miller Reis Rodrigues, Kevin Ngo, Rocky S. Tuan, Gwendolyn Sowa, James D. Kang, Nam Vo, Claudette M. St. Croix, Thais Cuperman, Pedro Pohl, Takashi Yurube, Thomas P. Lozito
Publikováno v:
Journal of Orthopaedic Research. 34:1466-1474
Neovascularization of intervertebral discs, a phenomenon considered pathological since normal discs are primarily avascular structures, occurs most frequently in annulus fibrosus (AF) of degenerated discs. Endothelial cells (ECs) are involved in this
Autor:
Nicolas E. Merzlak, Gwendolyn Sowa, Bryan N. Brown, Takashi Yurube, Richard E. Debski, Robert A. Hartman, Kevin Ngo, James D. Kang
Publikováno v:
Journal of Orthopaedic Research. 33:1255-1264
Mechanical loading is a salient factor in the progression of spinal disorders that contribute to back pain. Biological responses to loading modes like flexion/extension (F/E) in relevant spinal tissues remain unstudied. A novel, multi-axial experimen
Autor:
James D. Kang, Pedro Pohl, Nam Vo, Steven S. Shapiro, Gwendolyn Sowa, Laura J. Niedernhofer, Joon S. Lee, Paul D. Robbins, Kevin Ngo, Dong Wang, Peter J. Roughley, Peter Di, Adriana S. Leme
Publikováno v:
Spine. 42(20)
ADAMTS5-deficient and wild type (WT) mice were chronically exposed to tobacco smoke to investigate effects on intervertebral disc degeneration (IDD).The aim of this study was to demonstrate a role for ADAMTS5 in mediating tobacco smoking-induced IDD.