Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Kevin N. Pennington"'
Autor:
Pia Arrate, Terence S. Dermody, Pranav Danthi, Dean W. Ballard, Mark W. Hansberger, Kenneth B. Marcu, Kevin N. Pennington, Jacquelyn A. Campbell
Publikováno v:
Journal of Virology. 81:1360-1371
Reoviruses induce apoptosis both in cultured cells and in vivo. Apoptosis plays a major role in the pathogenesis of reovirus encephalitis and myocarditis in infected mice. Reovirus-induced apoptosis is dependent on the activation of transcription fac
Publikováno v:
Journal of Biological Chemistry. 280:43272-43279
Transcription factor NF-kappaB governs the expression of multiple genes involved in cell growth, immunity, and inflammation. Nuclear translocation of NF-kappaB is regulated from the cytoplasm by IkappaB kinase-beta (IKKbeta), which earmarks inhibitor
Publikováno v:
Journal of Biological Chemistry. 278:48903-48906
Initiation of the genetic programs for inflammation and immunity involves nuclear mobilization of transcription factor NF-κB. This signal-dependent process is controlled in part by the β-catalytic subunit of IκB kinase (IKKβ), which marks IκBα
Publikováno v:
Journal of Biological Chemistry. 274:22923-22931
The nuclear factor of kappaB (NF-kappaB) is a ubiquitous transcription factor that is key in the regulation of the immune response and inflammation. T cell receptor (TCR) cross-linking is in part required for activation of NF-kappaB, which is depende
Autor:
John H DiLiberti, Cindy Vavro, Ernest R Lanier, Kevin N. Pennington, Marty St. Clair, Cynthia R. Jackson, Megan E. Valentine, Samuel L. Katz, Ross E. McKinney, Catherine M. Wilfert
Publikováno v:
The Pediatric Infectious Disease Journal. 16:200-204
We evaluated the responses of HIV-infected children to a single dose of split-virus influenza vaccine and the relationship to viral load and other characteristics.Fifty-three HIV-infected children ages 1.8 to 13.2 years were given influenza vaccine f
Autor:
S D Kemp, Kevin N. Pennington, S Bloor, M H St Clair, B A Larder, Robert T. Schooley, A. Kohli, P R Harrigan, J M Lange
Publikováno v:
Journal of virology, 70(9), 5922-5929. American Society for Microbiology
Human immunodeficiency virus type 1 (HIV-1) isolates obtained prior to and during a combination therapy trial comparing zidovudine (AZT; 3'-azidothymidine) monotherapy with AZT plus 2',3'-dideoxyinosine (ddI) or AZT plus 2',3'-dideoxycytidine (ddC) w
Autor:
P. Richard Harrigan, Ray McKinnis, Lewis Lefkowitz, Jan W. Mulder, Helen C. Steel, Mark D. Moore, Brendan Larder, Ian Kinghorn, James Lavelle, Robert T. Schooley, David A. Cooper, Marty St. Clair, Joep M. A. Lange, Kevin N. Pennington, Carlos H. Ramirez-Ronda, James F. Rooney
Publikováno v:
Journal of Infectious Diseases. 173:1354-1366
A randomized controlled study was done to determine whether initial combination therapy with zidovudine and zalcitabine or zidovudine and didanosine would delay the emergence of zidovudine-resistant virus. Human immunodeficiency virus (HIV)-1-infecte
Autor:
GARY R. BURLESON, HERVÈ LEBREC, YUNG G. YANG, JOELLE D. IBANES, KEVIN N. PENNINGTON, LINDA S. BIRNBAUM
Publikováno v:
Toxicological Sciences. 29:40-47
Autor:
Mark W, Hansberger, Jacquelyn A, Campbell, Pranav, Danthi, Pia, Arrate, Kevin N, Pennington, Kenneth B, Marcu, Dean W, Ballard, Terence S, Dermody
Publikováno v:
Journal of virology. 81(3)
Reoviruses induce apoptosis both in cultured cells and in vivo. Apoptosis plays a major role in the pathogenesis of reovirus encephalitis and myocarditis in infected mice. Reovirus-induced apoptosis is dependent on the activation of transcription fac
Autor:
Carlos V. Paya, Gary D. Bren, Andrew D. Badley, Kevin N. Pennington, Susana Asin, Sergey Trushin
Publikováno v:
Journal of virology. 79(15)
Latently human immunodeficiency virus (HIV)-infected memory CD4+T cells represent the major obstacle to eradicating HIV from infected patients. Antigens, T-cell receptor (TCR) ligation, and phorbol esters can reactivate HIV from latency in a protein