Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kevin N Zhou"'
Autor:
Freeborn Rwere, Joseph R. White, Rafaela C. R. Hell, Xuan Yu, Xiaocong Zeng, Leslie McNeil, Kevin N. Zhou, Martin S. Angst, Che-Hong Chen, Daria Mochly-Rosen, Eric R. Gross
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Aldehyde dehydrogenase 2 (ALDH2) is critical for alcohol metabolism by converting acetaldehyde to acetic acid. In East Asian descendants, an inactive genetic variant in ALDH2, rs671, triggers an alcohol flushing response due to ac
Externí odkaz:
https://doaj.org/article/5332530b9af0442aabb1515ef3b4fc22
Autor:
Timothy N. Phoenix, Pratiti Bandopadhayay, David T.W. Jones, Henry Long, Claudia L. Kleinman, Volker Hovestadt, Keith L. Ligon, Stefan M. Pfister, Olaf Witt, Nada Jabado, François Aguet, Gad Getz, James M. McFarland, Jinghui Zhang, Suzanne J. Baker, Stefan Bielack, Michaela Nathrath, Christof M. Kramm, Gnana Prakash Balasubramanian, Natalie Jager, Uta Dirksen, David S. Ziegler, Maria Tsoli, J'Ya Hunter, Dana Novikov, Rushil Kumbhani, Jeromy J. Digiacomo, Madison S. Chacon, Elizabeth M. Gonzalez, Sophie D. Lu, Kevin N. Zhou, Sarah E. Dixon-Clarke, Alexandra L. Condurat, Xiaolong Chen, Audrey Baguette, Cecilia Sousa, Jayne Vogelzang, Kristine Pelton, Alexander Crane, Frank P.B. Dubois, Sudeepa Syamala, Ningxuan Zhou, Xin Wei, Phonepasong Arounleut, David W. Wu, Smruti Patel, Dayle K. Wang, Paloma Cejas, Jessica W. Tsai
Forkhead box R2 (FOXR2) is a forkhead transcription factor located on the X chromosome whose expression is normally restricted to the testis. In this study, we performed a pan-cancer analysis of FOXR2 activation across more than 10,000 adult and pedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::741da86f253c6e42c0401531e9509b90
https://doi.org/10.1158/0008-5472.c.6514136.v1
https://doi.org/10.1158/0008-5472.c.6514136.v1
Autor:
Timothy N. Phoenix, Pratiti Bandopadhayay, David T.W. Jones, Henry Long, Claudia L. Kleinman, Volker Hovestadt, Keith L. Ligon, Stefan M. Pfister, Olaf Witt, Nada Jabado, François Aguet, Gad Getz, James M. McFarland, Jinghui Zhang, Suzanne J. Baker, Stefan Bielack, Michaela Nathrath, Christof M. Kramm, Gnana Prakash Balasubramanian, Natalie Jager, Uta Dirksen, David S. Ziegler, Maria Tsoli, J'Ya Hunter, Dana Novikov, Rushil Kumbhani, Jeromy J. Digiacomo, Madison S. Chacon, Elizabeth M. Gonzalez, Sophie D. Lu, Kevin N. Zhou, Sarah E. Dixon-Clarke, Alexandra L. Condurat, Xiaolong Chen, Audrey Baguette, Cecilia Sousa, Jayne Vogelzang, Kristine Pelton, Alexander Crane, Frank P.B. Dubois, Sudeepa Syamala, Ningxuan Zhou, Xin Wei, Phonepasong Arounleut, David W. Wu, Smruti Patel, Dayle K. Wang, Paloma Cejas, Jessica W. Tsai
Supplementary Figure from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c77d20498973705d006fee266ee01a
https://doi.org/10.1158/0008-5472.22432439.v1
https://doi.org/10.1158/0008-5472.22432439.v1
Autor:
Timothy N. Phoenix, Pratiti Bandopadhayay, David T.W. Jones, Henry Long, Claudia L. Kleinman, Volker Hovestadt, Keith L. Ligon, Stefan M. Pfister, Olaf Witt, Nada Jabado, François Aguet, Gad Getz, James M. McFarland, Jinghui Zhang, Suzanne J. Baker, Stefan Bielack, Michaela Nathrath, Christof M. Kramm, Gnana Prakash Balasubramanian, Natalie Jager, Uta Dirksen, David S. Ziegler, Maria Tsoli, J'Ya Hunter, Dana Novikov, Rushil Kumbhani, Jeromy J. Digiacomo, Madison S. Chacon, Elizabeth M. Gonzalez, Sophie D. Lu, Kevin N. Zhou, Sarah E. Dixon-Clarke, Alexandra L. Condurat, Xiaolong Chen, Audrey Baguette, Cecilia Sousa, Jayne Vogelzang, Kristine Pelton, Alexander Crane, Frank P.B. Dubois, Sudeepa Syamala, Ningxuan Zhou, Xin Wei, Phonepasong Arounleut, David W. Wu, Smruti Patel, Dayle K. Wang, Paloma Cejas, Jessica W. Tsai
Supplementary Table from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010b86034115df2220900de572ba0818
https://doi.org/10.1158/0008-5472.22432385
https://doi.org/10.1158/0008-5472.22432385
FOXR2 is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits
Autor:
Jessica W. Tsai, Paloma Cejas, Dayle K. Wang, Smruti Patel, David W. Wu, Phonepasong Arounleut, Xin Wei, Ningxuan Zhou, Sudeepa Syamala, Frank P.B. Dubois, Alexander Crane, Kristine Pelton, Jayne Vogelzang, Cecilia Sousa, Audrey Baguette, Xiaolong Chen, Alexandra L. Condurat, Sarah E. Dixon-Clarke, Kevin N. Zhou, Sophie D. Lu, Elizabeth M. Gonzalez, Madison S. Chacon, Jeromy J. Digiacomo, Rushil Kumbhani, Dana Novikov, J'Ya Hunter, Maria Tsoli, David S. Ziegler, Uta Dirksen, Natalie Jager, Gnana Prakash Balasubramanian, Christof M. Kramm, Michaela Nathrath, Stefan Bielack, Suzanne J. Baker, Jinghui Zhang, James M. McFarland, Gad Getz, François Aguet, Nada Jabado, Olaf Witt, Stefan M. Pfister, Keith L. Ligon, Volker Hovestadt, Claudia L. Kleinman, Henry Long, David T.W. Jones, Pratiti Bandopadhayay, Timothy N. Phoenix
Publikováno v:
Cancer Res
Forkhead box R2 (FOXR2) is a forkhead transcription factor located on the X chromosome whose expression is normally restricted to the testis. In this study, we performed a pan-cancer analysis of FOXR2 activation across more than 10,000 adult and pedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b04fde1eafeb27aba2cd478be2c63a8
https://europepmc.org/articles/PMC9437574/
https://europepmc.org/articles/PMC9437574/
Autor:
Jessica W. Tsai, Paloma Cejas, Marissa Coppola, Dayle K. Wang, Smruti Patel, David W. Wu, Phonepasong Arounleut, Xin Wei, Ningxuan Zhou, Sudeepa Syamala, Frank P. Dubois, Kristine Pelton, Jayne Vogelzang, Cecilia Sousa, Audrey Baguette, Xiaolong Chen, Alexandra L. Condurat, Sarah E. Dixon-Clarke, Annarah Charles, Kevin N. Zhou, Sophie D. Lu, Elizabeth M. Gonzalez, Madison S. Chacon, Jeromy J. Digiacomo, Rushil Kumbhani, Dana Novikov, Maria Tsoli, David S. Ziegler, Uta Dirksen, Natalie Jager, Gnana Prakash Balasubramanian, Christof M. Kramm, Michaela Nathrath, Stefan Bielack, Suzanne J. Baker, Jinghui Zhang, James M. McFarland, Gad Getz, Francois Aguet, Nada Jabado, Olaf Witt, Stefan M. Pfister, Keith L. Ligon, Volker Hovestadt, Claudia Kleinman, Henry Long, David T. Jones, Pratiti Bandopadhayay, Timothy N. Phoenix
Publikováno v:
Cancer Research. 83:3562-3562
Background: Diffuse midline gliomas (DMGs) are a universally fatal brain tumor of childhood. While histone mutations are a critical tumor initiating event, they are insufficient to drive gliomagenesis. Histone mutations co-occur with somatic alterati
Autor:
Jessica W Tsai, Paloma Cejas, Dayle K Wang, Smruti Patel, David W Wu, Phonepasong Arounleut, Xin Wei, Ningxuan Zhou, Sudeepa Syamala, Frank P B Dubois, Alexander Crane, Kristine Pelton, Jayne Vogelzang, Cecilia Sousa, Audrey Baguette, Xiaolong Chen, Alexandra L Condurat, Sarah E Dixon-Clarke, Kevin N Zhou, Sophie D Lu, Elizabeth M Gonzalez, Madison S Chacon, Jeromy J Digiacomo, Rushil Kumbhani, Dana Novikov, J'Ya Hunter, Maria Tsoli, David S Ziegler, Uta Dirksen, Natalie Jager, Gnana Prakash Balasubramanian, Christof M Kramm, Michaela Nathrath, Stefan Bielack, Suzanne J Baker, Jinghui Zhang, James M McFarland, Gad Getz, Francois Aguet, Nada Jabado, Olaf Witt, Stefan M Pfister, Keith L Ligon, Claudia L Kleinman, Henry Long, David T W Jones, Pratiti Bandopadhayay, Timothy N Phoenix
BACKGROUND: Understanding how aberrant transcription factors (TFs) hijack normal development to induce oncogenesis is a critical question in oncology. Forkhead box (FOX) proteins are a superfamily of transcriptional regulators characterized by a fork
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07d62d7fc7e751a4d28899955a247a5d
Autor:
Jessica W. Tsai, Paloma Cejas, Dayle K. Wang, Smruti Patel, David W. Wu, Phonepasong Arounleut, Xin Wei, Ningxuan Zhou, Sudeepa Syamala, Frank P. Dubois, Kristine Pelton, Jayne Vogelzang, Cecilia Sousa, Audrey Baguette, Xiaolong Chen, Alexandra L. Condurat, Sarah E. Dixon-Clarke, Kevin N. Zhou, Sophie D. Lu, Elizabeth M. Gonzalez, Madison S. Chacon, Jeromy J. Digiacomo, Rushil Kumbhani, Dana Novikov, J'Ya Hunter, Maria Tsoli, David S. Ziegler, Uta Dirksen, Natalie Jager, Gnana Prakash Balasubramanian, Christof M. Kramm, Michaela Nathrath, Stefan Bielack, Suzanne J. Baker, Jinghui Zhang, James M. McFarland, Gad Getz, Francois Aguet, Nada Jabado, Olaf Witt, Stefan M. Pfister, Keith L. Ligon, Claudia Kleinman, Henry Long, David T. Jones, Pratiti Bandopadhayay, Timothy N. Phoenix
Publikováno v:
Cancer Research. 82:5730-5730
Background: Understanding how aberrant transcription factors (TFs) hijack normal development to induce oncogenesis is a critical question in oncology. Forkhead box (FOX) proteins are a superfamily of transcriptional regulators characterized by a fork
Autor:
Che-Hong Chen, Xiaocong Zeng, Daria Mochly-Rosen, Freeborn Rwere, Kevin N. Zhou, Leslie McNeil, Joseph R. White, Martin S. Angst, Eric R. Gross
Inefficient aldehyde metabolism by an aldehyde dehydrogenase 2 (ALDH2) genetic variant, ALDH2*2 (rs671), increases the risk of esophageal cancer with alcohol consumption. Here we tested the hypothesis that additional genetic differences in ALDH2 besi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a5cb1974a60422297b5c1113e46052